Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Splenic Diseases D013158 5 associated lipids
Trismus D014313 1 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
T-Lymphocytopenia, Idiopathic CD4-Positive D018344 1 associated lipids
Pyomyositis D052880 2 associated lipids
Myelitis, Transverse D009188 1 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Achondroplasia D000130 1 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Wynn RF et al. Azithromycin for cerebral toxoplasmosis in AIDS. 1993 Lancet pmid:8093526
Fortner JH et al. Tapetal effect of an azalide antibiotic following oral administration in beagle dogs. 1993 Fundam Appl Toxicol pmid:8405779
Bailey RL et al. Randomised controlled trial of single-dose azithromycin in treatment of trachoma. 1993 Lancet pmid:8102427
Narcio Reyes LE et al. [Efficacy and safety of azithromycin in the treatment of female genital Chlamydia trachomatis infections]. 1993 Ginecol Obstet Mex pmid:8406112
Nahata MC et al. Pharmacokinetics of azithromycin in pediatric patients after oral administration of multiple doses of suspension. 1993 Antimicrob. Agents Chemother. pmid:8383944
Vaara M Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. 1993 Antimicrob. Agents Chemother. pmid:8383945
Brown ST et al. Azithromycin, rifabutin, and rifapentine for treatment and prophylaxis of Mycobacterium avium complex in rats treated with cyclosporine. 1993 Antimicrob. Agents Chemother. pmid:8384809
Cameron DJ Effectiveness of early Lyme disease treatment. 1993 Am. J. Med. pmid:8388627
Melski JW et al. Primary and secondary erythema migrans in central Wisconsin. 1993 Arch Dermatol pmid:8389536
Amacher DE et al. Preclinical toxicology studies with azithromycin: genetic toxicology evaluation. 1993 Mutat. Res. pmid:7685497
Gomberg MA and MashkilleÄ­son AL [Use of azithromycin in long existing urogenital chlamydia infections and its association with primary syphilis]. 1993 Antibiot. Khimioter. pmid:8060178
Sidorenko SV [Azithromycin--an antibiotic of the azalide group]. 1993 Antibiot. Khimioter. pmid:8060181
Lopatkin NA et al. [Use of azithromycin ("Sumamded") in the treatment of infectious-inflammatory diseases of the lower urinary tract and male genitalia]. 1993 Antibiot. Khimioter. pmid:8060189
Saba J et al. Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. 1993 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8112357
Weiss LM et al. Efficacy of azithromycin for treating Babesia microti infection in the hamster model. 1993 J. Infect. Dis. pmid:8228366
Holdcroft C Two new macrolide antibiotics: clarithromycin and azithromycin. 1993 Nurse Pract pmid:8380492
Spangler SK and Appelbaum PC Oxyrase, a method which avoids CO2 in the incubation atmosphere for anaerobic susceptibility testing of antibiotics affected by CO2. 1993 J. Clin. Microbiol. pmid:8381817
Gingras BA and Jensen JB Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. 1993 Am. J. Trop. Med. Hyg. pmid:8394660
Workowski KA et al. Azithromycin in chlamydial urethritis. 1993 JAMA pmid:8411548
Genç M et al. An economic evaluation of screening for Chlamydia trachomatis in adolescent males. 1993 JAMA pmid:8411572