| MeSH term | MeSH ID | Detail |
|---|---|---|
| Corneal Endothelial Cell Loss | D055954 | 1 associated lipids |
| Male Urogenital Diseases | D052801 | 1 associated lipids |
| Frontal Sinusitis | D015522 | 1 associated lipids |
| Paratyphoid Fever | D010284 | 1 associated lipids |
| Asymptomatic Infections | D058345 | 1 associated lipids |
| Hyper-IgM Immunodeficiency Syndrome | D053306 | 1 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Gibson PG et al. | Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. | 2017 | Lancet | pmid:28687413 |
| Molefe NI et al. | Oral administration of azithromycin ameliorates trypanosomosis in Trypanosoma congolense-infected mice. | 2017 | Parasitol. Res. | pmid:28674747 |
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| Sanders AM et al. | Burden of trachoma in five counties of Eastern Equatoria state, South Sudan: Results from population-based surveys. | 2017 | PLoS Negl Trop Dis | pmid:28614375 |
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| Venekamp RP and Schilder AGM | Clinical failure is more common in young children with acute otitis media who receive a short course of antibiotics compared with standard duration. | 2017 | Evid Based Med | pmid:28404603 |
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| Marks M et al. | Mass drug administration of azithromycin for trachoma reduces the prevalence of genital Chlamydia trachomatis infection in the Solomon Islands. | 2016 | Sex Transm Infect | pmid:26888658 |
| Economopoulos KP et al. | Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase. | 2016 | Diabetes Obes Metab | pmid:26876427 |
| Kang JY et al. | Long-term azithromycin ameliorates not only airway inflammation but also remodeling in a murine model of chronic asthma. | 2016 | Pulm Pharmacol Ther | pmid:26778828 |
| Sridhar S et al. | High recurrence rate supports need for secondary prophylaxis in non-HIV patients with disseminated mycobacterium avium complex infection: a multi-center observational study. | 2016 | BMC Infect. Dis. | pmid:26861696 |
| Peters RP et al. | Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome. | 2016 | Sex Transm Dis | pmid:26760182 |
| Hodgson D et al. | The Effects of Azithromycin in Treatment-Resistant Cough: A Randomized, Double-Blind, Placebo-Controlled Trial. | 2016 | Chest | pmid:26836927 |
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| Gratrix J et al. | A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men. | 2016 | Sex Transm Dis | pmid:26760180 |
| Kumaraswamy M et al. | Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia. | 2016 | J. Antimicrob. Chemother. | pmid:26832758 |
| Arikan S et al. | Effect of Topically Applied Azithromycin on Corneal Epithelial and Endothelial Apoptosis in a Rat Model of Corneal Alkali Burn. | 2016 | Cornea | pmid:26751994 |
| Zhou T et al. | Fabrication of a Selective and Sensitive Sensor Based on Molecularly Imprinted Polymer/Acetylene Black for the Determination of Azithromycin in Pharmaceuticals and Biological Samples. | 2016 | PLoS ONE | pmid:26820753 |
| Russell DW et al. | Disease phenotyping in chronic obstructive pulmonary disease: the neutrophilic endotype. | 2016 | Curr Opin Pulm Med | pmid:26717512 |
| Manavi K et al. | Comparison of doxycycline with azithromycin in treatment of pharyngeal chlamydia infection. | 2016 | Int J STD AIDS | pmid:26511655 |
| Williams KM et al. | Fluticasone, Azithromycin, and Montelukast Treatment for New-Onset Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation. | 2016 | Biol. Blood Marrow Transplant. | pmid:26475726 |
| Nicholson TT et al. | Assessing potential risks of treatment with long-term azithromycin in COPD patients: long-term oxygen users beware? | 2016 | Ir J Med Sci | pmid:26502012 |
| Deguchi T et al. | Multidrug-Resistant Mycoplasma genitalium Is Increasing. | 2016 | Clin. Infect. Dis. | pmid:26494825 |
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| Kasten G et al. | Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery. | 2016 | Drug Dev Ind Pharm | pmid:26266961 |
| Osborne LG et al. | Enteric fever in a British soldier from Sierra Leone. | 2016 | J R Army Med Corps | pmid:26243802 |
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