Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Asymptomatic Infections D058345 1 associated lipids
Trichiasis D058457 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Tick Bites D064927 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Authors Title Published Journal PubMed Link
Arrieta A et al. High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media. 2003 Antimicrob. Agents Chemother. pmid:14506028
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Khandekarf R and Mohammed AJ Outcome of azithromycin treatment of active trachoma in Omani school children. 2003 Sep-Nov East. Mediterr. Health J. pmid:16450533
Imamura Y et al. Azithromycin inhibits MUC5AC production induced by the Pseudomonas aeruginosa autoinducer N-(3-Oxododecanoyl) homoserine lactone in NCI-H292 Cells. 2004 Antimicrob. Agents Chemother. pmid:15328111
Nielsen HU et al. Nasopharyngeal pathogens in children with acute otitis media in a low-antibiotic use country. 2004 Int. J. Pediatr. Otorhinolaryngol. pmid:15302145
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Zuckerman JM Macrolides and ketolides: azithromycin, clarithromycin, telithromycin. 2004 Infect. Dis. Clin. North Am. pmid:15308279
Kvien TK et al. Three month treatment of reactive arthritis with azithromycin: a EULAR double blind, placebo controlled study. 2004 Ann. Rheum. Dis. pmid:15308521
Ishimatsu Y et al. Macrolide antibiotics induce apoptosis of human peripheral lymphocytes in vitro. 2004 Int. J. Antimicrob. Agents pmid:15325428
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Mak DB et al. Control of genital chlamydial infection in the Kimberley region of Western Australia. 2004 Med. J. Aust. pmid:14709130
Aihara Y et al. Stevens-Johnson syndrome associated with azithromycin followed by transient reactivation of herpes simplex virus infection. 2004 Allergy pmid:14674950
Tiukinhoy SD et al. Novel echogenic drug-immunoliposomes for drug delivery. 2004 Invest Radiol pmid:14734925
Yang YZ [Death of a case caused by anaphylaxis to azithromycin]. 2004 Zhonghua Er Ke Za Zhi pmid:15733367
McLean CA et al. The emergence of Neisseria gonorrhoeae with decreased susceptibility to Azithromycin in Kansas City, Missouri, 1999 to 2000. 2004 Sex Transm Dis pmid:14743069
Kyebambe P Incomplete Reiter's arthritis in a 23 year old nursing mother. 2004 Afr Health Sci pmid:15687073
Matic V et al. Antipneumococcal activities of two novel macrolides, GW 773546 and GW 708408, compared with those of erythromycin, azithromycin, clarithromycin, clindamycin, and telithromycin. 2004 Antimicrob. Agents Chemother. pmid:15504828
Kosowska K et al. Activities of two novel macrolides, GW 773546 and GW 708408, compared with those of telithromycin, erythromycin, azithromycin, and clarithromycin against Haemophilus influenzae. 2004 Antimicrob. Agents Chemother. pmid:15504829
Levy SB et al. The misuse of antibiotics. 2004 Med Ethics (Burlingt Mass) pmid:15915579
Fernandez AD et al. Azithromycin modulates murine immune responses to pneumococcal conjugate vaccine and inhibits nasal clearance of bacteria. 2004 J. Infect. Dis. pmid:15499531
Pokrovskaia EV [Final confirmation of inefficiency of antibiotics in secondary prevention of coronary heart disease. Results of PROVE IT (gatifloxacin trial) and ACES]. 2004 Kardiologiia pmid:15477798
Mueller M et al. Toll-like receptors 2 and 4 do not contribute to clearance of Chlamydophila pneumoniae in mice, but are necessary for the release of monokines. 2004 Immunobiology pmid:15638128
Hyodo E et al. Effect of azithromycin therapy on coronary circulation in patients with coronary artery disease. 2004 Am. J. Cardiol. pmid:15566918
Khamitov RF et al. [Significance of antibacterial therapy of Chlamydophila pneumoniae infection in patients with bronchial asthma]. 2004 Ter. Arkh. pmid:15575487
Gillis RJ and Iglewski BH Azithromycin retards Pseudomonas aeruginosa biofilm formation. 2004 J. Clin. Microbiol. pmid:15583321
Tokgöz B et al. Effects of azithromycin on cyclosporine-induced gingival hyperplasia in renal transplant patients. 2004 Transplant. Proc. pmid:15621128
Chen GF et al. [Follow up of 16 cases with congenital toxoplasmosis treated with azithromycin]. 2004 Zhonghua Er Ke Za Zhi pmid:14990100
Kasahara K et al. Longterm azithromycin therapy for three patients with chronic lower respiratory tract infections. 2004 J. Infect. Chemother. pmid:14991517