Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Reproductive Tract Infections D060737 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Protozoan Infections D011528 6 associated lipids
Tick Bites D064927 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Ritchlin CT Treatment of reactive arthritis with azithromycin. 2005 Curr Rheumatol Rep pmid:15918991
Máiz Carro L [Long-term treatment with azithromycin in a patient with idiopathic bronchiectasis]. 2005 Arch. Bronconeumol. pmid:15919012
Drago L et al. In vitro selection of resistance to clarithromycin in Streptococcus pneumoniae clinical isolates. 2005 J Chemother pmid:15920900
Fellerhoff B et al. High risk of schizophrenia and other mental disorders associated with chlamydial infections: hypothesis to combine drug treatment and adoptive immunotherapy. 2005 Med. Hypotheses pmid:15922095
Jain SK et al. Antimicrobial-resistant Shigella sonnei: limited antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility. 2005 Pediatr. Infect. Dis. J. pmid:15933557
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Koch DE et al. Azithromycin extraction from municipal wastewater and quantitation using liquid chromatography/mass spectrometry. 2005 J Chromatogr A pmid:15941034
Patton DL et al. Significant reduction in inflammatory response in the macaque model of chlamydial pelvic inflammatory disease with azithromycin treatment. 2005 J. Infect. Dis. pmid:15942902
Handrick W et al. [Pulmonary infection due to Mycobacterium malmoense]. 2005 Pneumologie pmid:15944898
Barlam TF Expedited treatment for partners of patients with gonorrhea and/or chlamydial infection: impact on rates of persistence or recurrence. 2005 Postgrad Med pmid:15948359
Wang JS et al. [Preparation of lung targeting azithromycin liposomes and its tissue distribution in mice]. 2005 Yao Xue Xue Bao pmid:15952603
Floret D et al. [Action to be taken when facing one or more cases of whooping-cough]. 2005 Arch Pediatr pmid:15961299
Parnham MJ et al. Modulation of neutrophil and inflammation markers in chronic obstructive pulmonary disease by short-term azithromycin treatment. 2005 Eur. J. Pharmacol. pmid:15964564
Krayenbuehl PA et al. Effect of macrolides on peripheral arterial disease depends on patient selection and adequate treatment. 2005 Eur J Vasc Endovasc Surg pmid:15967691
Yates B et al. Azithromycin reverses airflow obstruction in established bronchiolitis obliterans syndrome. 2005 Am. J. Respir. Crit. Care Med. pmid:15976371
Prescott WA and Johnson CE Antiinflammatory therapies for cystic fibrosis: past, present, and future. 2005 Pharmacotherapy pmid:15977917
Eschenauer G et al. Azithromycin-warfarin interaction: are we fishing with a red herring? 2005 Pharmacotherapy pmid:15977924
Desmond N et al. Acceptability of azithromycin for the control of trachoma in Northern Tanzania. 2005 Trans. R. Soc. Trop. Med. Hyg. pmid:15979657
Göbel A et al. Occurrence and sorption behavior of sulfonamides, macrolides, and trimethoprim in activated sludge treatment. 2005 Environ. Sci. Technol. pmid:15984773
Jover F et al. Possible azithromycin-associated hiccups. 2005 J Clin Pharm Ther pmid:15985056
Spiro DM et al. Antibiotic-induced mesenteric adenopathy in an intussusception mouse model: a randomized, controlled trial. 2005 J. Pediatr. Gastroenterol. Nutr. pmid:15990628
Iacopini F et al. One-week once-daily triple therapy with esomeprazole, levofloxacin and azithromycin compared to a standard therapy for Helicobacter pylori eradication. 2005 Dig Liver Dis pmid:15996628
Girard D et al. Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models. 2005 J. Antimicrob. Chemother. pmid:16002421
Palmieri F et al. Pulmonary cryptosporidiosis in an AIDS patient: successful treatment with paromomycin plus azithromycin. 2005 Int J STD AIDS pmid:16004637
Dinwiddie R Anti-inflammatory therapy in cystic fibrosis. 2005 J. Cyst. Fibros. pmid:16005266
Spooner K et al. Azithromcyin might not protect against Treponema pallidum infection or reactivation in HIV type 1-infected patients. 2005 Clin. Infect. Dis. pmid:16007551
Baltussen RM et al. Cost-effectiveness of trachoma control in seven world regions. 2005 Ophthalmic Epidemiol pmid:16019692
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Rennie RP and Ibrahim KH Antimicrobial resistance in Haemophilus influenzae: how can we prevent the inevitable? Commentary on antimicrobial resistance in H. influenzae based on data from the TARGETed surveillance program. 2005 Clin. Infect. Dis. pmid:16032558
West ES et al. Surgery for Trichiasis, Antibiotics to prevent Recurrence (STAR) Clinical Trial methodology. 2005 Ophthalmic Epidemiol pmid:16033749
Bliziotis I et al. Regression of subcorneal pustular dermatosis type of IgA pemphigus lesions with azithromycin. 2005 J. Infect. pmid:16038746
Saiman L et al. Heterogeneity of treatment response to azithromycin in patients with cystic fibrosis. 2005 Am. J. Respir. Crit. Care Med. pmid:16040785
van Oosterhout JJ et al. A community-based study of the incidence of trimethoprim-sulfamethoxazole-preventable infections in Malawian adults living with HIV. 2005 J. Acquir. Immune Defic. Syndr. pmid:16044018
Kuper H et al. Participatory evaluations of trachoma control programmes in eight countries. 2005 Trop. Med. Int. Health pmid:16045463
Matsui H et al. Azithromycin inhibits the formation of flagellar filaments without suppressing flagellin synthesis in Salmonella enterica serovar typhimurium. 2005 Antimicrob. Agents Chemother. pmid:16048953
Glasheen JJ et al. The risk of overanticoagulation with antibiotic use in outpatients on stable warfarin regimens. 2005 J Gen Intern Med pmid:16050864
Mitchell WM and Stratton CW Chlamydia pneumoniae and acute coronary syndrome. 2005 N. Engl. J. Med. pmid:16080250
Gabrielli M et al. Azithromycin on soluble cell adhesion molecules and markers of inflammation in survivors of an acute coronary syndrome. 2005 Am. Heart J. pmid:16084141
Sharma S and El-Refaey H Vaginal azithromycin and misoprostol before surgical abortion. 2005 Fertil. Steril. pmid:16084904
Shinkai M et al. Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells. 2006 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:16085674
Murray JJ et al. Efficacy and safety of a novel, single-dose azithromycin microsphere formulation versus 10 days of levofloxacin for the treatment of acute bacterial sinusitis in adults. 2005 Otolaryngol Head Neck Surg pmid:16087013
Marple BF Editorial commentary: dilemma in trial design: do current study designs adequately evaluate effectiveness antibiotic in ABRS? 2005 Otolaryngol Head Neck Surg pmid:16087014
Barrett B et al. Validated HPLC-MS-MS method for determination of azithromycin in human plasma. 2005 Anal Bioanal Chem pmid:16091946
Elitok B et al. Efficacy of azithromycin dihydrate in treatment of cryptosporidiosis in naturally infected dairy calves. 2005 Jul-Aug J. Vet. Intern. Med. pmid:16095179
Taylor-Robinson D and Boman J The failure of antibiotics to prevent heart attacks. 2005 BMJ pmid:16096289
Silvers JA and Champney WS Accumulation and turnover of 23S ribosomal RNA in azithromycin-inhibited ribonuclease mutant strains of Escherichia coli. 2005 Arch. Microbiol. pmid:16096836
Rotschild M et al. Autoantibodies against bactericidal/permeability-increasing protein (BPI-ANCA) in cystic fibrosis patients treated with azithromycin. 2005 Clin. Exp. Med. pmid:16096858
Wagner T et al. Effects of azithromycin on clinical isolates of Pseudomonas aeruginosa from cystic fibrosis patients. 2005 Chest pmid:16100186
Verleden GM et al. Effect of azithromycin on bronchiectasis and pulmonary function in a heart-lung transplant patient with severe chronic allograft dysfunction: a case report. 2005 J. Heart Lung Transplant. pmid:16102464
Rekart ML et al. The impact of syphilis mass treatment one year later: self-reported behaviour change among participants. 2005 Int J STD AIDS pmid:16105193
Shibata Y et al. [Evaluation of anti-inflammatory effect of macrolides on macrophages]. 2004 Jpn J Antibiot pmid:16108591
Mizunoe T et al. [The mechanism of apoptosis induction in lymphocytes by macrolide antibiotics and the related intra-cellular molecular structure]. 2004 Jpn J Antibiot pmid:16108600
Gaynor BD et al. Topical ocular antibiotics induce bacterial resistance at extraocular sites. 2005 Br J Ophthalmol pmid:16113356
Ollivier V et al. Modulation of tissue factor expression by rapamycin and FK-506 in lipopolysaccharide-stimulated human mononuclear cells and serum-stimulated aortic smooth muscle cells. 2005 Thromb. Haemost. pmid:16113783
Block SL et al. A comparison of 5 days of therapy with cefdinir or azithromycin in children with acute otitis media: a multicenter, prospective, single-blind study. 2005 Clin Ther pmid:16117986
Milstone A et al. Prospective observational study of patient-reported outcomes for azithromycin versus usual care in the treatment of bacterial acute exacerbation of chronic bronchitis. 2005 Clin Ther pmid:16117993
Gillis RJ et al. Molecular basis of azithromycin-resistant Pseudomonas aeruginosa biofilms. 2005 Antimicrob. Agents Chemother. pmid:16127063
Ríos AM et al. Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia. 2005 Antimicrob. Agents Chemother. pmid:16127085
Frota LC et al. Helicobacter pylori eradication using tetracycline and furazolidone versus amoxicillin and azithromycin in lansoprazole based triple therapy: an open randomized clinical trial. 2005 Apr-Jun Arq Gastroenterol pmid:16127567
Bouwman JJ et al. Azithromycin reduces Chlamydia pneumoniae-induced attenuation of eNOS and cGMP production by endothelial cells. 2005 Eur. J. Clin. Invest. pmid:16128864
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Graziani F et al. Clinical evaluation of piroxicam-FDDF and azithromycin in the prevention of complications associated with impacted lower third molar extraction. 2005 Pharmacol. Res. pmid:16140544
Shitrit D et al. Long-term azithromycin use for treatment of bronchiolitis obliterans syndrome in lung transplant recipients. 2005 J. Heart Lung Transplant. pmid:16143268
Salgado HR and Roncari AF Microbiological assay for the determination of azithromycin in ophthalmic solutions. 2005 Yao Xue Xue Bao pmid:16144322
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Rouquette-Loughlin CE et al. Characterization of the MacA-MacB efflux system in Neisseria gonorrhoeae. 2005 J. Antimicrob. Chemother. pmid:16162665
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Labro MT et al. Accumulation of azithromycin and roxithromycin in tracheal epithelial fetal cell lines expressing wild type or mutated cystic fibrosis transmembrane conductance regulator protein (CFTR). 2005 J Chemother pmid:16167517
Pradal U et al. Long-term azithromycin in cystic fibrosis: another possible mechanism of action? 2005 J Chemother pmid:16167518
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Burton MJ et al. A randomised controlled trial of azithromycin following surgery for trachomatous trichiasis in the Gambia. 2005 Br J Ophthalmol pmid:16170117
Rodriguez CN et al. Quinolone and azithromycin-resistant Neisseria meningitidis serogroup C causing urethritis in a heterosexual man. 2005 Int J STD AIDS pmid:16176640
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Tripathi R et al. Blood schizontocidal activity of azithromycin and its combination with alpha/beta arteether against multi-drug resistant Plasmodium yoelii nigeriensis, a novel MDR parasite model for antimalarial screening. 2005 Parasitology pmid:16178350
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Valdes A and Johnson JR Septic pleuritis and abdominal abscess formation caused by Rhodococcus equi in a foal. 2005 J. Am. Vet. Med. Assoc. pmid:16190597
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Chaudhary C et al. A pilot study on antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Nepal. 2005 Sex Transm Dis pmid:16205307
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Cárceles CM et al. Pharmacokinetics of azithromycin after i.v. and i.m. administration to sheep. 2005 J. Vet. Pharmacol. Ther. pmid:16207311
Don DM et al. Antimicrobial therapy for children with adenotonsillar hypertrophy and obstructive sleep apnea: a prospective randomized trial comparing azithromycin vs placebo. 2005 Otolaryngol Head Neck Surg pmid:16213930
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Blasi F et al. Azithromycin and lower respiratory tract infections. 2005 Expert Opin Pharmacother pmid:16218893
Galetin A et al. Prediction of time-dependent CYP3A4 drug-drug interactions: impact of enzyme degradation, parallel elimination pathways, and intestinal inhibition. 2006 Drug Metab. Dispos. pmid:16221752
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Drehobl MA et al. Single-dose azithromycin microspheres vs clarithromycin extended release for the treatment of mild-to-moderate community-acquired pneumonia in adults. 2005 Chest pmid:16236879
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Sharma JB et al. Comparative efficacy of two regimens in syndromic management of lower genital infections. 2006 Arch. Gynecol. Obstet. pmid:16247610