Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Reproductive Tract Infections D060737 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Protozoan Infections D011528 6 associated lipids
Tick Bites D064927 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Authors Title Published Journal PubMed Link
Graybill JR and Bocanegra R Treatment alternatives for Mycobacterium kansasii. 2001 J. Antimicrob. Chemother. pmid:11266413
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Mizen L The activity of antibiotics against Legionella pneumophila: in vitro and in vivo studies. 2001 J. Antimicrob. Chemother. pmid:11222573
Amsden GW and Gray CL Serum and WBC pharmacokinetics of 1500 mg of azithromycin when given either as a single dose or over a 3 day period in healthy volunteers. 2001 J. Antimicrob. Chemother. pmid:11152432
Giacometti A et al. Activity of buforin II alone and in combination with azithromycin and minocycline against Cryptosporidium parvum in cell culture. 2001 J. Antimicrob. Chemother. pmid:11152438
Gieffers J et al. Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic treatment. 2001 Circulation pmid:11157684
Weiss LM et al. The treatment of babesiosis. 2001 N. Engl. J. Med. pmid:11236789
Nagai K et al. Activities of a new fluoroketolide, HMR 3787, and its (des)-fluor derivative RU 64399 compared to those of telithromycin, erythromycin A, azithromycin, clarithromycin, and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae and S. pyogenes. 2001 Antimicrob. Agents Chemother. pmid:11600391
De Diego JI et al. Comparison of amoxicillin and azithromycin in the prevention of recurrent acute otitis media. 2001 Int. J. Pediatr. Otorhinolaryngol. pmid:11249979
Ioannidis JP et al. Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for upper respiratory tract infections. 2001 J. Antimicrob. Chemother. pmid:11679557
Contopoulos-Ioannidis DG et al. Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for lower respiratory tract infections. 2001 J. Antimicrob. Chemother. pmid:11679558
Laurent J et al. A randomized comparison of four omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. 2001 Aliment. Pharmacol. Ther. pmid:11683693
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Gray RH et al. Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda. 2001 Am. J. Obstet. Gynecol. pmid:11717659
Intrauterine devices: antibiotic prophylaxis not necessary during insertion. 2001 Prescrire Int pmid:11718174
Golledge CL and Riley TV The efficacy of an antibiotic protocol for community-acquired pneumonia. 2001 Med. J. Aust. pmid:11700844
Toro C et al. [Prevalence of primary Helicobacter pylori resistance to eight antimicrobial agents in a hospital in Madrid]. 2001 Rev Esp Quimioter pmid:11704771
Tajima T et al. [Discussions on PRSP and BLNAR]. 2001 Jpn J Antibiot pmid:12638161
Samarendra P et al. QT prolongation associated with azithromycin/amiodarone combination. 2001 Pacing Clin Electrophysiol pmid:11707055
Hand WL and Hand DL Characteristics and mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes. 2001 Int. J. Antimicrob. Agents pmid:11711255
Treadway G and Reisman A Tolerability of 3-day, once-daily azithromycin suspension versus standard treatments for community-acquired paediatric infectious diseases. 2001 Int. J. Antimicrob. Agents pmid:11711256
Page RL et al. Possible interaction between intravenous azithromycin and oral cyclosporine. 2001 Pharmacotherapy pmid:11714218
Amsden GW Advanced-generation macrolides: tissue-directed antibiotics. 2001 Int. J. Antimicrob. Agents pmid:11574189
Malizia T et al. Interaction between piroxicam and azithromycin during distribution to human periodontal tissues. 2001 J. Periodontol. pmid:11577945
Salopek-Rabatić J Chlamydial conjunctivitis in contact lens wearers: successful treatment with single dose azithromycin. 2001 CLAO J pmid:11725983
Butler T Effect of increased inoculum of Salmonella typhi on MIC of azithromycin and resultant growth characteristics. 2001 J. Antimicrob. Chemother. pmid:11733476
Dillon JA et al. Reduced susceptibility to azithromycin and high percentages of penicillin and tetracycline resistance in Neisseria gonorrhoeae isolates from Manaus, Brazil, 1998. 2001 Sex Transm Dis pmid:11518869
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Doern GV Antimicrobial use and the emergence of antimicrobial resistance with Streptococcus pneumoniae in the United States. 2001 Clin. Infect. Dis. pmid:11524718
Noedl H et al. Antimalarial activity of azithromycin, artemisinin and dihydroartemisinin in fresh isolates of Plasmodium falciparum in Thailand. 2001 Acta Trop. pmid:11495642
Fraser-Hurt N et al. Efficacy of oral azithromycin versus topical tetracycline in mass treatment of endemic trachoma. 2001 Bull. World Health Organ. pmid:11477966
Skerk V et al. Azithromycin and doxycycline in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum: significance of duration of clinical symptoms. 2001 Drugs Exp Clin Res pmid:11822223
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Martinez SM et al. Azithromycin prophylaxis during a hospitalwide outbreak of a pertussis-like illness. 2001 Infect Control Hosp Epidemiol pmid:11876458
Mendes CM et al. In vitro susceptibility of gram-positive cocci isolated from skin and respiratory tract to azithromycin and twelve other antimicrobial agents. 2001 Braz J Infect Dis pmid:11779453
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Najib NM et al. Bioequivalence assessment of Azomycin (Julphar, UAE) as compared to Zithromax (Pfizer, USA)--two brands of azithromycin--in healthy human volunteers. 2001 Biopharm Drug Dispos pmid:11745903
Skerk V et al. Azithromycin in the treatment of chronic prostatitis caused by Chlamydia trachomatis. 2001 J Chemother pmid:11806631
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Dreses-Werringloer U et al. Effects of azithromycin and rifampin on Chlamydia trachomatis infection in vitro. 2001 Antimicrob. Agents Chemother. pmid:11600348
Littler WA Clindamycin suspension and endocarditis prophylaxis. 2001 Br Dent J pmid:11352383
Ikegaya S et al. [Effect of azithromycin on cytokine production by THP-1 cells]. 2001 Jpn J Antibiot pmid:12575425
Tateda K et al. Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa. 2001 Antimicrob. Agents Chemother. pmid:11353657
Kato T et al. [Effect of azithromycin on cytokine production in human bronchial epithelial cell line, BEAS-2B]. 2001 Jpn J Antibiot pmid:12575426
Pechère JC Azithromycin reduces the production of virulence factors in Pseudomonas aeruginosa by inhibiting quorum sensing. 2001 Jpn J Antibiot pmid:12575427
Holm SO et al. Comparison of two azithromycin distribution strategies for controlling trachoma in Nepal. 2001 Bull. World Health Organ. pmid:11285662
Tateda K et al. [MIC, sub-MIC of macrolide resistant bacteria--special reference to their quorum-sensing system]. 2001 Jpn J Antibiot pmid:12575433
Frick KD et al. Cost-effectiveness of trachoma control measures: comparing targeted household treatment and mass treatment of children. 2001 Bull. World Health Organ. pmid:11285663
Bailey R and Lietman T The SAFE strategy for the elimination of trachoma by 2020: will it work? 2001 Bull. World Health Organ. pmid:11285668
Sorvillo F et al. Incidence and determinants of Pseudomonas aeruginosa infection among persons with HIV: association with hospital exposure. 2001 Am J Infect Control pmid:11287873
Edelstein PH et al. In vitro activity of gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and its pharmacokinetics in guinea pigs with L. pneumophila pneumonia. 2001 Antimicrob. Agents Chemother. pmid:11451675
Rubinstein E Comparative safety of the different macrolides. 2001 Int. J. Antimicrob. Agents pmid:11574199
Skerk V et al. Duration of clinical symptoms in female patients with acute urethral syndrome caused by Chlamydia trachomatis treated with azithromycin or doxycycline. 2001 J Chemother pmid:11330365
Rodríguez Núñez A et al. [Chemoprophylaxis of meningococcal disease with azithromycin and ciprofloxacin]. 2001 An. Esp. Pediatr. pmid:11333489
Grand A et al. [Subacute infectious endocarditis due to the agent of cat scratch fever: Bartonella henselae]. 2001 Arch Mal Coeur Vaiss pmid:11265556