| MeSH term | MeSH ID | Detail |
|---|---|---|
| Reproductive Tract Infections | D060737 | 1 associated lipids |
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
| Pneumonia, Lipid | D011017 | 2 associated lipids |
| Protozoan Infections | D011528 | 6 associated lipids |
| Tick Bites | D064927 | 1 associated lipids |
| Granulomatous Mastitis | D058890 | 1 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kurdowska A et al. | The effect of azithromycin and clarithromycin on ex vivo interleukin-8 (IL-8) release from whole blood and IL-8 production by human alveolar macrophages. | 2001 | J. Antimicrob. Chemother. | pmid:11389120 |
| Chokephaibulkit K et al. | Intestinal parasitic infections among human immunodeficiency virus-infected and -uninfected children hospitalized with diarrhea in Bangkok, Thailand. | 2001 | Southeast Asian J. Trop. Med. Public Health | pmid:12041552 |
| Solera J et al. | Azithromycin and gentamicin therapy for the treatment of humans with brucellosis. | 2001 | Clin. Infect. Dis. | pmid:11170962 |
| Ioannidis JP et al. | Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for upper respiratory tract infections. | 2001 | J. Antimicrob. Chemother. | pmid:11679557 |
| Contopoulos-Ioannidis DG et al. | Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for lower respiratory tract infections. | 2001 | J. Antimicrob. Chemother. | pmid:11679558 |
| Laurent J et al. | A randomized comparison of four omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. | 2001 | Aliment. Pharmacol. Ther. | pmid:11683693 |
| Damianov L et al. | [Treatment of genital chlamydia infections with Sumamed]. | 2001 | Akush Ginekol (Sofiia) | pmid:11519320 |
| Doern GV | Antimicrobial use and the emergence of antimicrobial resistance with Streptococcus pneumoniae in the United States. | 2001 | Clin. Infect. Dis. | pmid:11524718 |
| Castor D et al. | Antibiotic resistant N. gonorrhoeae in Trinidad and Tobago. | 2001 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:11785665 |
| van der Griend B et al. | An uncommon cause of a destructive vulval lesion. | 2001 | Aust N Z J Obstet Gynaecol | pmid:11787928 |
| Holm SO et al. | Comparison of two azithromycin distribution strategies for controlling trachoma in Nepal. | 2001 | Bull. World Health Organ. | pmid:11285662 |
| Frick KD et al. | Cost-effectiveness of trachoma control measures: comparing targeted household treatment and mass treatment of children. | 2001 | Bull. World Health Organ. | pmid:11285663 |
| Bailey R and Lietman T | The SAFE strategy for the elimination of trachoma by 2020: will it work? | 2001 | Bull. World Health Organ. | pmid:11285668 |
| Chetchotisakd P et al. | Maintenance therapy of melioidosis with ciprofloxacin plus azithromycin compared with cotrimoxazole plus doxycycline. | 2001 Jan-Feb | Am. J. Trop. Med. Hyg. | pmid:11425157 |
| Baumann U et al. | Buccal adherence of Pseudomonas aeruginosa in patients with cystic fibrosis under long-term therapy with azithromycin. | 2001 Jan-Feb | Infection | pmid:11261763 |
| Kent JR et al. | Azithromycin: an assessment of its pharmacokinetics and therapeutic potential in CAPD. | 2001 Jul-Aug | Perit Dial Int | pmid:11587400 |
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| Lorenz J et al. | Treatment outcomes in acute exacerbations of chronic bronchitis: comparison of macrolides and moxifloxacin from the patient perspective. | 2001 Mar-Apr | J. Int. Med. Res. | pmid:11393351 |
| Postma MJ et al. | Cost-effectiveness of partner pharmacotherapy in screening women for asymptomatic infection with Chlamydia Trachomatis. | 2001 May-Jun | Value Health | pmid:11705188 |
| Akritopoulou-Zanze I and Sowin TJ | Solid-phase synthesis of macrolide analogues. | 2001 May-Jun | J Comb Chem | pmid:11350254 |
| Aberg JA et al. | Presence of macrolide resistance in respiratory flora of HIV-Infected patients receiving either clarithromycin or azithromycin for Mycobacterium avium complex prophylaxis. | 2001 Nov-Dec | HIV Clin Trials | pmid:11742432 |
| Biswas S | In-vitro antimalarial activity of azithromycin against chloroquine sensitive and chloroquine resistant Plasmodium falciparum. | 2001 Oct-Dec | J Postgrad Med | pmid:11832638 |
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| Hand WI and Hand DL | [Mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes]. | 2002 | Antibiot. Khimioter. | pmid:12516190 |
| Di Paolo A et al. | Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily. | 2002 | Pharmacol. Res. | pmid:12457629 |
| Chiu LM et al. | Pharmacokinetics of intravenous azithromycin and ceftriaxone when administered alone and concurrently to healthy volunteers. | 2002 | J. Antimicrob. Chemother. | pmid:12461037 |
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| Kamau FN et al. | Isocratic liquid chromatographic method for the analysis of azithromycin and its structurally related substances in bulk samples. | 2002 | J Chromatogr Sci | pmid:12433117 |
| Tyteca D et al. | Azithromycin, a lysosomotropic antibiotic, has distinct effects on fluid-phase and receptor-mediated endocytosis, but does not impair phagocytosis in J774 macrophages. | 2002 | Exp. Cell Res. | pmid:12441132 |
| Aguirrebengoa K et al. | [Endocarditis due to Bartonella henselae on a native valve. A new case with some notable aspects]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:12372243 |
| Ivashkin VT et al. | Azithromycin in a triple therapy for H.pylori eradication in active duodenal ulcer. | 2002 | World J. Gastroenterol. | pmid:12378634 |
| House D et al. | Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever. | 2002 | J. Infect. Dis. | pmid:12134261 |
| Wallace Jr RJ et al. | Repeat positive cultures in Mycobacterium intracellulare lung disease after macrolide therapy represent new infections in patients with nodular bronchiectasis. | 2002 | J. Infect. Dis. | pmid:12134265 |
| Cheng H et al. | Synthesis and SAR of azalide 3,6-ketal aromatic derivatives as potent Gram-positive and Gram-negative antibacterial agents. | 2002 | Bioorg. Med. Chem. Lett. | pmid:12161150 |
| Kawashima M et al. | Inhibitory effects of 14-membered ring macrolide antibiotics on bleomycin-induced acute lung injury. | 2002 | Lung | pmid:12182159 |
| Yee CL et al. | Tendon or joint disorders in children after treatment with fluoroquinolones or azithromycin. | 2002 | Pediatr. Infect. Dis. J. | pmid:12182376 |
| Clark C et al. | In vitro selection of resistance in Haemophilus influenzae by amoxicillin-clavulanate, cefpodoxime, cefprozil, azithromycin, and clarithromycin. | 2002 | Antimicrob. Agents Chemother. | pmid:12183253 |
| Blandizzi C et al. | Distribution of azithromycin in plasma and tonsil tissue after repeated oral administration of 10 or 20 milligrams per kilogram in pediatric patients. | 2002 | Antimicrob. Agents Chemother. | pmid:11959610 |
| Ekici A et al. | Effect of azithromycin on the severity of bronchial hyperresponsiveness in patients with mild asthma. | 2002 | J Asthma | pmid:11990233 |
| Mohler AM | Treatment of streptococcal pharyngitis. | 2002 | Am Fam Physician | pmid:11996411 |
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| Ng LK et al. | Mutation in 23S rRNA associated with macrolide resistance in Neisseria gonorrhoeae. | 2002 | Antimicrob. Agents Chemother. | pmid:12183262 |
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| Prunier AL et al. | Clinical isolates of Staphylococcus aureus with ribosomal mutations conferring resistance to macrolides. | 2002 | Antimicrob. Agents Chemother. | pmid:12183270 |
| Treadway G et al. | The safety of azithromycin in the treatment of adults with community-acquired respiratory tract infections. | 2002 | Int. J. Antimicrob. Agents | pmid:11932140 |
| [Unfortunately without effectiveness: chlamydia eradication after infarct]. | 2002 | MMW Fortschr Med | pmid:12014269 | |
| Suriawinata A and Min AD | A 33-year-old woman with jaundice after azithromycin use. | 2002 | Semin. Liver Dis. | pmid:12016551 |
| Evans AT et al. | Azithromycin for acute bronchitis: a randomised, double-blind, controlled trial. | 2002 | Lancet | pmid:12020525 |
| King A et al. | Erythromycin susceptibility of viridans streptococci from the normal throat flora of patients treated with azithromycin or clarithromycin. | 2002 | Clin. Microbiol. Infect. | pmid:11952721 |
| Lisby JG et al. | [Bacteremia and meningitis caused by Streptococcus pneumoniae during treatment with azithromycin]. | 2002 | Ugeskr. Laeg. | pmid:12043408 |
| Nishikawa T | [Comment on the contribution by Weigl CB et al. "Papillomatosis confluens et reticularis"]. | 2002 | Hautarzt | pmid:12063751 |
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| Babl FE et al. | Experimental acute otitis media due to nontypeable Haemophilus influenzae: comparison of high and low azithromycin doses with placebo. | 2002 | Antimicrob. Agents Chemother. | pmid:12069974 |
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| Muirhead GJ et al. | The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers. | 2002 | Br J Clin Pharmacol | pmid:11879258 |
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| Adimora AA | Treatment of uncomplicated genital Chlamydia trachomatis infections in adults. | 2002 | Clin. Infect. Dis. | pmid:12353204 |
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| Chandrupatla S et al. | Azithromycin-induced intrahepatic cholestasis. | 2002 | Dig. Dis. Sci. | pmid:12395890 |
| Nagai K et al. | Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries. | 2002 | Antimicrob. Agents Chemother. | pmid:11796375 |
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| Zhou F et al. | High accuracy mass measurement of peptides with internal calibration using a dual electrospray ionization sprayer system for protein identification. | 2002 | Rapid Commun. Mass Spectrom. | pmid:11870887 |
| Krudsood S et al. | A comparative clinical trial of combinations of dihydroartemisinin plus azithromycin and dihydroartemisinin plus mefloquine for treatment of multidrug resistant falciparum malaria. | 2002 | Southeast Asian J. Trop. Med. Public Health | pmid:12693587 |
| Burton MJ et al. | Azithromycin for the treatment and control of trachoma. | 2002 | Expert Opin Pharmacother | pmid:11829725 |
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| Desta Z et al. | In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin. | 2002 | J Clin Psychopharmacol | pmid:11910261 |
| Ito N and Kudo S | [Case of polycystic lung disease with mixed infections due to Aspergillus and Mycobacterium fortuitum successfully treated by AZM]. | 2002 | Jpn J Antibiot | pmid:12664928 |
| Kim MK et al. | Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model. | 2002 | Antimicrob. Agents Chemother. | pmid:12234843 |
| Smith SR et al. | A double-blind placebo-controlled trial of azithromycin as an adjunct to non-surgical treatment of periodontitis in adults: clinical results. | 2002 | J. Clin. Periodontol. | pmid:11846850 |
| Wu ML et al. | Enterocolonic Mycobacterium avium-intracellulare. | 2002 | Arch. Pathol. Lab. Med. | pmid:11860323 |
| Cascio A et al. | Clarithromycin versus azithromycin in the treatment of Mediterranean spotted fever in children: a randomized controlled trial. | 2002 | Clin. Infect. Dis. | pmid:11740701 |
| Schachter J and Dawson CR | Elimination of blinding trachoma. | 2002 | Curr. Opin. Infect. Dis. | pmid:12686881 |
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| Strle F and Maraspin V | Is azithromycin treatment associated with prolongation of the Q-Tc interval? | 2002 | Wien. Klin. Wochenschr. | pmid:12708094 |
| Dawson CR and Schachter J | Should trachoma be treated with antibiotics? | 2002 | Lancet | pmid:11812548 |
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| Lentino JR and Krasnicka B | Association between initial empirical therapy and decreased length of stay among veteran patients hospitalized with community acquired pneumonia. | 2002 | Int. J. Antimicrob. Agents | pmid:11814769 |
| Phillips P et al. | Azithromycin prophylaxis for Mycobacterium avium complex during the era of highly active antiretroviral therapy: evaluation of a provincial program. | 2002 | Clin. Infect. Dis. | pmid:11774085 |
| Dai G et al. | [Researching some sensitivity factor of bioassay method on the antibiotics pharmacokinetics]. | 2002 | Hunan Yi Ke Da Xue Xue Bao | pmid:12575254 |
| Dzelalija B et al. | Randomized trial of azithromycin in the prophylaxis of Mediterranean spotted fever. | 2002 | Acta Med Croatica | pmid:12596623 |
| Nalbanski B and Nalbanski A | [Treatment of Chlamydia trachomatis with azatril]. | 2002 | Akush Ginekol (Sofiia) | pmid:11935692 |
| Krumov G et al. | [Treatment of chlamydial cervicitis with azatril]. | 2002 | Akush Ginekol (Sofiia) | pmid:11935693 |