Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Reproductive Tract Infections D060737 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Protozoan Infections D011528 6 associated lipids
Tick Bites D064927 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Authors Title Published Journal PubMed Link
Harris JA et al. Safety and efficacy of azithromycin in the treatment of community-acquired pneumonia in children. 1998 Pediatr. Infect. Dis. J. pmid:9802626
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Soepandi P et al. The pattern of micro-organisms and the efficacy of new macrolide in acute lower respiratory tract infections. 1998 Respirology pmid:9692520
Fang X et al. [Inhibitory activity of azithromycin on biofilm synthesis and synergism between azithromycin and fleroxacin on Pseudomonas aeruginosa in biofilms]. 1998 Zhonghua Jie He He Hu Xi Za Zhi pmid:11360505
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Kober MB and Mason BA Colonization of the female genital tract by resistant Ureaplasma urealyticum treated successfully with azithromycin. 1998 Clin. Infect. Dis. pmid:9709898
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Oldfield EC et al. Once weekly azithromycin therapy for prevention of Mycobacterium avium complex infection in patients with AIDS: a randomized, double-blind, placebo-controlled multicenter trial. 1998 Clin. Infect. Dis. pmid:9524832
Fuentes F et al. Postanitbiotic and sub-MIC effects of azithromycin and isepamicin against Staphylococcus aureus and Escherichia coli. 1998 Antimicrob. Agents Chemother. pmid:9527796
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Muhlestein JB et al. Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. 1998 Circulation pmid:9495296
Woldtvedt BR et al. Possible increased anticoagulation effect of warfarin induced by azithromycin. 1998 Ann Pharmacother pmid:9496419
Goldstein EJ et al. Trovafloxacin compared with levofloxacin, ofloxacin, ciprofloxacin, azithromycin and clarithromycin against unusual aerobic and anaerobic human and animal bite-wound pathogens. 1998 J. Antimicrob. Chemother. pmid:9578167
Miller SR et al. Delayed cellulitis associated with conservative therapy for breast cancer. 1998 J Surg Oncol pmid:9579371
Levert H et al. Azithromycin impact on neutrophil oxidative metabolism depends on exposure time. 1998 Inflammation pmid:9561928
Trevisani L et al. A four-day low dose triple therapy regimen for the treatment of Helicobacter pylori infection. 1998 Am. J. Gastroenterol. pmid:9517646
Bowden FJ and Savage J Donovanosis: treatment with azithromycin. 1998 Int J STD AIDS pmid:9518024
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Roblin PM and Hammerschlag MR Microbiologic efficacy of azithromycin and susceptibilities to azithromycin of isolates of Chlamydia pneumoniae from adults and children with community-acquired pneumonia. 1998 Antimicrob. Agents Chemother. pmid:9449287
Jaffé A et al. Long-term azithromycin may improve lung function in children with cystic fibrosis. 1998 Lancet pmid:9482305
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Thalhammer F et al. Azithromycin-related toxic effects of digitoxin. 1998 Br J Clin Pharmacol pmid:9489601
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Champney WS and Burdine R Azithromycin and clarithromycin inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells. 1998 Curr. Microbiol. pmid:9425251
Can antibiotics prevent heart disease? 1998 Harv Heart Lett pmid:9619136
Bass JW et al. Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. 1998 Pediatr. Infect. Dis. J. pmid:9655532
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Dionisio D et al. Chronic cryptosporidiosis in patients with AIDS: stable remission and possible eradication after long-term, low dose azithromycin. 1998 J. Clin. Pathol. pmid:9602688
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Bayoumi AM and Redelmeier DA Preventing Mycobacterium avium complex in patients who are using protease inhibitors: a cost-effectiveness analysis. 1998 AIDS pmid:9727572
Moyle GJ et al. Once weekly azithromycin as prophylaxis against recurrence of non-tuberculous mycobacterial infections in HIV-1-positive individuals. 1998 AIDS pmid:9727581
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Andersen SL et al. Successful double-blinded, randomized, placebo-controlled field trial of azithromycin and doxycycline as prophylaxis for malaria in western Kenya. 1998 Clin. Infect. Dis. pmid:9455524
Chia JK et al. Azithromycin for the treatment of cat-scratch disease. 1998 Clin. Infect. Dis. pmid:9455538
Peterson J and Treadway G Impact of community-based azithromycin treatment of trachoma on carriage and resistance of Streptococcus pneumoniae. 1998 Clin. Infect. Dis. pmid:9455579
Holmberg SD et al. Possible effectiveness of clarithromycin and rifabutin for cryptosporidiosis chemoprophylaxis in HIV disease. HIV Outpatient Study (HOPS) Investigators. 1998 JAMA pmid:9459473
Rajyaguru JM and Muszynski MJ Sensitization of Burkholderia cepacia to antibiotics by cationic drugs. 1998 J. Antimicrob. Chemother. pmid:9533472
Gruber F et al. Treatment of confluent and reticulated papillomatosis with azithromycin. 1998 Clin. Exp. Dermatol. pmid:9894368
Aubert JD et al. Function of human alveolar macrophages after a 3-day course of azithromycin in healthy volunteers. 1998 Pulm Pharmacol Ther pmid:10101742
Bauriedel G et al. Azithromycin, Chlamydia pneumoniae, and intimal thickening. 1998 Circulation pmid:9826328
Ward TT et al. Randomized, open-label trial of azithromycin plus ethambutol vs. clarithromycin plus ethambutol as therapy for Mycobacterium avium complex bacteremia in patients with human immunodeficiency virus infection. Veterans Affairs HIV Research Consortium. 1998 Clin. Infect. Dis. pmid:9827282
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