Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Reproductive Tract Infections D060737 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Protozoan Infections D011528 6 associated lipids
Tick Bites D064927 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Grimes M et al. Two mutations associated with macrolide resistance in Treponema pallidum: increasing prevalence and correlation with molecular strain type in Seattle, Washington. 2012 Sex Transm Dis pmid:23191949
Chen XS Azithromycin versus penicillin G benzathine for early syphilis. 2012 Sex Transm Dis pmid:23060081
Soge OO et al. Emergence of increased azithromycin resistance during unsuccessful treatment of Neisseria gonorrhoeae infection with azithromycin (Portland, OR, 2011). 2012 Sex Transm Dis pmid:23064537
Leeyaphan C et al. Treatment Outcomes for Rectal Lymphogranuloma Venereum in Men Who Have Sex with Men Using Doxycycline, Azithromycin, or Both: A Review of Clinical Cases. 2017 Sex Transm Dis pmid:28282652
Ito S et al. Haemophilus influenzae Isolated From Men With Acute Urethritis: Its Pathogenic Roles, Responses to Antimicrobial Chemotherapies, and Antimicrobial Susceptibilities. 2017 Sex Transm Dis pmid:28282645
Muldoon EG et al. Treponema pallidum azithromycin resistance in Dublin, Ireland. 2012 Sex Transm Dis pmid:23001265
Ehret JM et al. A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. 1996 Jul-Aug Sex Transm Dis pmid:8836018
Batteiger BE Azithromycin Efficacy in Asymptomatic Rectal Chlamydial Infection in Men Who Have Sex With Men: A More Definitive Answer Soon? 2017 Sex Transm Dis pmid:28604482
Zhu BY et al. Surveillance of antimicrobial susceptibilities of Neisseria gonorrhoeae in Nanning, China, 2000 to 2012. 2014 Sex Transm Dis pmid:25013979
Zhou P et al. Azithromycin treatment failure among primary and secondary syphilis patients in Shanghai. 2010 Sex Transm Dis pmid:20644500
Smith KS et al. Biological and Behavioral Factors Associated With Positive Chlamydia Retests. 2017 Sex Transm Dis pmid:28608791
Kissinger PJ et al. Azithromycin Treatment Failure for Chlamydia trachomatis Among Heterosexual Men With Nongonococcal Urethritis. 2016 Sex Transm Dis pmid:27631353
Vandepitte J et al. High prevalence of ciprofloxacin-resistant gonorrhea among female sex workers in Kampala, Uganda (2008-2009). 2014 Sex Transm Dis pmid:24622633
Singh AE et al. Neisseria gonorrhoeae multiantigen sequence typing is beneficial in further characterizing gonococcal populations in Alberta, Canada. 2013 Sex Transm Dis pmid:23945428
Chaudhary C et al. A pilot study on antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Nepal. 2005 Sex Transm Dis pmid:16205307
Carlin EM and Barton SE Azithromycin as a cost-effective treatment for nongonococcal urethritis in men. 1997 Sex Transm Dis pmid:9018784
Steingrímsson O et al. Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men. 1994 Jan-Feb Sex Transm Dis pmid:8140488
Hillis SD et al. Doxycycline and azithromycin for prevention of chlamydial persistence or recurrence one month after treatment in women. A use-effectiveness study in public health settings. 1998 Sex Transm Dis pmid:9437777
Hottes TS et al. Cephalosporin and azithromycin susceptibility in Neisseria gonorrhoeae isolates by site of infection, British Columbia, 2006 to 2011. 2013 Sex Transm Dis pmid:23250301
Stamm WE et al. A randomized, double-blind study comparing single-dose rifalazil with single-dose azithromycin for the empirical treatment of nongonococcal urethritis in men. 2007 Sex Transm Dis pmid:17297383
Herchline TE and Inkrott BP Resistance trends in Neisseria gonorrhoeae in southwestern Ohio. 2010 Sex Transm Dis pmid:19901861
Van Damme K et al. Evaluation of azithromycin resistance in Treponema pallidum specimens from Madagascar. 2009 Sex Transm Dis pmid:19901863
Weinstein SA and Stiles BG A review of the epidemiology, diagnosis and evidence-based management of Mycoplasma genitalium. 2011 Sex Health pmid:21592428
McCormick DF et al. Prevention and control of sexually transmissible infections among hotel-based female sex workers in Dhaka, Bangladesh. 2013 Sex Health pmid:24262217
Robertson A et al. Case report: lymphogranuloma venereum in New Zealand. 2008 Sex Health pmid:19061558
Stratov I et al. Azithromycin: more lethal than chloramphenicol? 2013 Sex Health pmid:23448962
Renault CA et al. Time to clearance of Chlamydia trachomatis ribosomal RNA in women treated for chlamydial infection. 2011 Sex Health pmid:21371385
Jones S et al. The tip of the iceberg: opportunistic screening for Chlamydia trachomatis in asymptomatic patients attending a young people's health clinic reveals a high prevalence--a pilot study. 2004 Sex Health pmid:16334993
Suriawinata A and Min AD A 33-year-old woman with jaundice after azithromycin use. 2002 Semin. Liver Dis. pmid:12016551
Pedro-Botet ML and Sabrià M Legionellosis. 2005 Semin Respir Crit Care Med pmid:16388431
Berger BW Lyme disease. 1993 Semin Dermatol pmid:8312152
Seguí Díaz M [What is the best treatment for urogenital Chlamydia trachomatis infection?] Semergen pmid:27068255
Wawer MJ et al. AIDS intervention in Uganda. 1995 Science pmid:7570005
Topp E et al. Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. 2016 Sci. Total Environ. pmid:27096634
Sidhu H et al. Risk assessment of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30463165
Sidhu H et al. Plant toxicity and accumulation of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30340267
Sidhu H et al. Retention-release of ciprofloxacin and azithromycin in biosolids and biosolids-amended soils. 2019 Sci. Total Environ. pmid:30196217
Sidhu H et al. Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: Microbial toxicity and earthworm responses. 2019 Sci. Total Environ. pmid:30195128
Friesen J et al. Natural immunization against malaria: causal prophylaxis with antibiotics. 2010 Sci Transl Med pmid:20630856
Ratzinger F et al. Azithromycin suppresses CD4(+) T-cell activation by direct modulation of mTOR activity. 2014 Sci Rep pmid:25500904
Gensel JC et al. Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment. 2017 Sci Rep pmid:28057928
Wang A et al. Effects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia. 2016 Sci Rep pmid:27405358
Menzel M et al. Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients. 2016 Sci Rep pmid:27350308
Zeng J et al. Mechanism of azithromycin inhibition of HSL synthesis in Pseudomonas aeruginosa. 2016 Sci Rep pmid:27075730
Pansieri C et al. Ureaplasma, bronchopulmonary dysplasia, and azithromycin in European neonatal intensive care units: a survey. 2014 Sci Rep pmid:24518104
Das MC et al. Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. 2016 Sci Rep pmid:27000525
Gualdoni GA et al. Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation. 2015 Sci Rep pmid:26152605
Feary DJ et al. Lawsonia intracellularis proliferative enteropathy in a foal. 2007 Schweiz. Arch. Tierheilkd. pmid:17410971
Dickerson FB et al. A double-blind trial of adjunctive azithromycin in individuals with schizophrenia who are seropositive for Toxoplasma gondii. 2009 Schizophr. Res. pmid:19464853
Kuzman I et al. Azithromycin for treatment of community acquired pneumonia caused by Legionella pneumophila: a retrospective study. 1995 Scand. J. Infect. Dis. pmid:8588143