Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Birth Weight D001724 23 associated lipids
Bites, Human D001734 2 associated lipids
Blister D001768 16 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Burns D002056 34 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Laing RB et al. Clinical features, outcome and survival from cerebral toxoplasmosis in Edinburgh AIDS patients. 1996 Int J STD AIDS pmid:8876356
Tansey MJ and Moe JB Severe neutropenia and prophylactic doses of rifabutin. 1996 Lancet pmid:8950911
Sefton AM et al. Azithromycin in the treatment of periodontal disease. Effect on microbial flora. 1996 J. Clin. Periodontol. pmid:8951627
Griffith DE et al. Varying dosages of rifabutin affect white blood cell and platelet counts in human immunodeficiency virus--negative patients who are receiving multidrug regimens for pulmonary Mycobacterium avium complex disease. 1996 Clin. Infect. Dis. pmid:8953085
Prophylactic antibiotic receives speedy FDA approval to reduce MAC disease in advanced HIV. 1996 AIDS Patient Care STDS pmid:11361569
Azithromycin and OIs. 1996 AIDS Patient Care STDS pmid:11361699
Bertoni G et al. Triple therapy with azithromycin, omeprazole, and amoxicillin is highly effective in the eradication of Helicobacter pylori: a controlled trial versus omeprazole plus amoxicillin. 1996 Am. J. Gastroenterol. pmid:8607489
Di Mario F et al. Azithromycin for the cure of Helicobacter pylori infection. 1996 Am. J. Gastroenterol. pmid:8607490
Dupont C et al. Microbiological findings about pulmonary cryptosporidiosis in two AIDS patients. 1996 J. Clin. Microbiol. pmid:8748314
Wildfeuer A et al. Uptake of azithromycin by various cells and its intracellular activity under in vivo conditions. 1996 Antimicrob. Agents Chemother. pmid:8787883
Okamoto T and Sekiguchi T [Clinical studies on azithromycin in pediatrics]. 1996 Jpn J Antibiot pmid:8986557
Toyonaga Y et al. [Pharmacokinetic and clinical evaluation of azithromycin using fine granules or capsules in the pediatric patients]. 1996 Jpn J Antibiot pmid:8988410
Okumura A and Kuno K [Pharmacokinetic and clinical evaluation of azithromycin in pediatrics]. 1996 Jpn J Antibiot pmid:8988411
Kobayashi Y et al. [Clinical study of a macrolide antibiotic, azithromycin, in pediatric patients]. 1996 Jpn J Antibiot pmid:8988412
O'Doherty B Azithromycin versus penicillin V in the treatment of paediatric patients with acute streptococcal pharyngitis/tonsillitis. Paediatric Azithromycin Study Group. 1996 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8922571
Amsden GW Erythromycin, clarithromycin, and azithromycin: are the differences real? 1996 Jan-Feb Clin Ther pmid:8851453
Preac Mursic V et al. Kill kinetics of Borrelia burgdorferi and bacterial findings in relation to the treatment of Lyme borreliosis. 1996 Jan-Feb Infection pmid:8852456
Baradaran-Dilmaghani R and Stanek G In vitro susceptibility of thirty Borrelia strains from various sources against eight antimicrobial chemotherapeutics. 1996 Jan-Feb Infection pmid:8852472
Strle F et al. Azithromycin and doxycycline for treatment of Borrelia culture-positive erythema migrans. 1996 Jan-Feb Infection pmid:8852473
Fontán PA et al. Haemophilus influenzae type b exoproducts induce chemotaxis and macrolide antibiotic release by human polymorphonuclear leukocytes. 1996 Jan-Feb Chemotherapy pmid:8751269
Ehret JM et al. A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. 1996 Jul-Aug Sex Transm Dis pmid:8836018
Lane G Increased hypoprothrombinemic effect of warfarin possibly induced by azithromycin. 1996 Jul-Aug Ann Pharmacother pmid:8826581
Diculencu D et al. [The postantibiotic effect of azithromycin on respiratory pathogens]. 1996 Jul-Dec Rev Med Chir Soc Med Nat Iasi pmid:9455450
Carlin EM and Barton SE Azithromycin as the first-line treatment of non-gonococcal urethritis (NGU): a study of follow-up rates, contact attendance and patients' treatment preference. 1996 May-Jun Int J STD AIDS pmid:8799780
Shanks GD et al. Azithromycin prophylaxis prevents epidemic dysentery. 1996 May-Jun Trans. R. Soc. Trop. Med. Hyg. pmid:8758091
Adam D et al. Re: A. Bauernfeind et al.: Comparative pharmacodynamics of clarithromycin and azithromycin against respiratory pathogens (Infection 23 [1995] 316-321) 1996 May-Jun Infection pmid:8811372
Vranes J Effect of subinhibitory concentrations of ceftazidime, ciprofloxacin, and azithromycin on the hemagglutination and adherence of uropathogenic Escherichia coli strains. 1996 May-Jun Chemotherapy pmid:8983884
Ichimiya T et al. The influence of azithromycin on the biofilm formation of Pseudomonas aeruginosa in vitro. 1996 May-Jun Chemotherapy pmid:8983885
Galova K et al. Multicenter randomized study of two once daily regimens in the initial management of community-acquired respiratory tract infections in 163 children: azithromycin versus ceftibuten. 1996 May-Jun Chemotherapy pmid:8983893
Burke SM Azithromycin: only once a day. 1996 May-Jun MCN Am J Matern Child Nurs pmid:8857402
Ripa S et al. A linear model for the pharmacokinetics of azithromycin in healthy volunteers. 1996 Nov-Dec Chemotherapy pmid:8957574
D'Amico R ICAAC update on opportunistic infections. 1996 Nov-Dec Posit Aware pmid:11363974
Wendel TD 1-day azithromycin was as effective as 7-day doxycycline for nongonococcal urethritis syndrome in men. 1996 Nov-Dec ACP J. Club pmid:8912627
Peeling RW and Brunham RC Chlamydiae as pathogens: new species and new issues. 1996 Oct-Dec Emerging Infect. Dis. pmid:8969247
Biebuyck XA Comparison of azithromycin and co-amoxiclav in the treatment of acute tracheobronchitis and acute infectious exacerbations of chronic bronchitis in adults. Azithromycin Study Group. 1996 Sep-Oct J. Int. Med. Res. pmid:8895044
New DL et al. Vertically transmitted babesiosis. 1997 J. Pediatr. pmid:9255211
Pacifico L and Chiesa C Efficacy of three-day azithromycin vs. ten-day penicillin V in the treatment of streptococcal pharyngitis. 1997 Pediatr. Infect. Dis. J. pmid:9154566
Fernandez-Obregon AC Azithromycin for the treatment of acne. 1997 Int. J. Dermatol. pmid:9159021
Nightingale CH Pharmacokinetics and pharmacodynamics of newer macrolides. 1997 Pediatr. Infect. Dis. J. pmid:9109156
Block SL Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. 1997 Pediatr. Infect. Dis. J. pmid:9109158
Tarlow MJ et al. Future indications for macrolides. 1997 Pediatr. Infect. Dis. J. pmid:9109159
Dawson CR et al. A comparison of oral azithromycin with topical oxytetracycline/polymyxin for the treatment of trachoma in children. 1997 Clin. Infect. Dis. pmid:9114186
Caselli M et al. Short-term low-dose triple therapy with azithromycin, metronidazole and lansoprazole appears highly effective for the eradication of Helicobacter pylori. 1997 Eur J Gastroenterol Hepatol pmid:9031898
Arévalo Morles C et al. Donovanosis: treatment with azithromycin. 1997 Int J STD AIDS pmid:9043983
Hoepelman IM et al. A short (3-day) course of azithromycin tablets versus a 10-day course of amoxycillin-clavulanic acid (co-amoxiclav) in the treatment of adults with lower respiratory tract infections and effects on long-term outcome. 1997 Int. J. Antimicrob. Agents pmid:9552709
Gupta S et al. Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction. 1997 Circulation pmid:9244203
Vazifeh D et al. Cellular accumulation of the new ketolide RU 64004 by human neutrophils: comparison with that of azithromycin and roxithromycin. 1997 Antimicrob. Agents Chemother. pmid:9333032
Nilius AM et al. Variability in susceptibilities of Haemophilus influenzae to clarithromycin and azithromycin due to medium pH. 1997 J. Clin. Microbiol. pmid:9163435
Rajyaguru JM and Muszynski MJ Enhancement of Burkholderia cepacia antimicrobial susceptibility by cationic compounds. 1997 J. Antimicrob. Chemother. pmid:9338485
Odenholt I et al. Studies of the killing kinetics of benzylpenicillin, cefuroxime, azithromycin, and sparfloxacin on bacteria in the postantibiotic phase. 1997 Antimicrob. Agents Chemother. pmid:9371360