Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Moraxellaceae Infections D045828 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
O'Day DM et al. Ocular pharmacokinetics of orally administered azithromycin in rabbits. 1994 J Ocul Pharmacol pmid:7714407
Donowitz GR Tissue-directed antibiotics and intracellular parasites: complex interaction of phagocytes, pathogens, and drugs. 1994 Clin. Infect. Dis. pmid:7893881
Beale AS and Upshon PA Characteristics of murine model of genital infection with Chlamydia trachomatis and effects of therapy with tetracyclines, amoxicillin-clavulanic acid, or azithromycin. 1994 Antimicrob. Agents Chemother. pmid:7811001
Verdon MS et al. Pilot study of azithromycin for treatment of primary and secondary syphilis. 1994 Clin. Infect. Dis. pmid:7811868
Raszka WV et al. Multifocal M. intracellulare osteomyelitis in an immunocompetent child. 1994 Clin Pediatr (Phila) pmid:7813141
Carlier MB et al. Accumulation, release and subcellular localization of azithromycin in phagocytic and non-phagocytic cells in culture. 1994 Int J Tissue React pmid:7558665
Management of genital Chlamydia trachomatis infections. 1994 Drug Ther Bull pmid:7635012
Wang JH et al. Azithromycin in the treatment of pneumonia caused by Chlamydia pneumoniae: report of a case. 1994 J. Formos. Med. Assoc. pmid:7866068
Cynamon MH et al. Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7979270
Klemens SP and Cynamon MH Activities of azithromycin and clarithromycin against nontuberculous mycobacteria in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7979271
Schönwald S et al. Three-day azithromycin compared with ten-day roxithromycin treatment of atypical pneumonia. 1994 Scand. J. Infect. Dis. pmid:7747094
Schwab JC et al. Localization of azithromycin in Toxoplasma gondii-infected cells. 1994 Antimicrob. Agents Chemother. pmid:7979295
[Azithromycin--an innovative macrolide antibiotic for 3-day-therapy]. 1994 Immun. Infekt. pmid:7982710
Rodriguez WJ and Wiedermann BL The role of newer oral cephalosporins, fluoroquinolones, and macrolides in the treatment of pediatric infections. 1994 Adv Pediatr Infect Dis pmid:8123221
Eisenberg E and Barza M Azithromycin and clarithromycin. 1994 Curr Clin Top Infect Dis pmid:8086122
Kanatani MS and Guglielmo BJ The new macrolides. Azithromycin and clarithromycin. 1994 West. J. Med. pmid:8128699
Pfefferkorn ER and Borotz SE Comparison of mutants of Toxoplasma gondii selected for resistance to azithromycin, spiramycin, or clindamycin. 1994 Antimicrob. Agents Chemother. pmid:8141576
Bermudez LE et al. Rifabutin and sparfloxacin but not azithromycin inhibit binding of Mycobacterium avium complex to HT-29 intestinal mucosal cells. 1994 Antimicrob. Agents Chemother. pmid:8067766
Uzun O et al. Efficacy of a three-day course of azithromycin in the treatment of community-acquired pneumococcal pneumonia. Preliminary report. 1994 J Chemother pmid:8071680
Marchi M et al. [Azithromycin-omeprazole. Treatment for the eradication of Helicobacter pylori]. 1994 Minerva Gastroenterol Dietol pmid:8204705