Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Moraxellaceae Infections D045828 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

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What genes are associated with Azithramycine?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Mortensen JE et al. In vitro activity of oral antimicrobial agents against clinical isolates of Pasteurella multocida. 1998 Diagn. Microbiol. Infect. Dis. pmid:9554176
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Hoppe JE and Bryskier A In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). 1998 Antimicrob. Agents Chemother. pmid:9559823
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Miller SR et al. Delayed cellulitis associated with conservative therapy for breast cancer. 1998 J Surg Oncol pmid:9579371
Scaglione F and Rossoni G Comparative anti-inflammatory effects of roxithromycin, azithromycin and clarithromycin. 1998 J. Antimicrob. Chemother. pmid:9579712
Goldstein EJ et al. Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated from skin and soft tissue infections in humans. 1998 Antimicrob. Agents Chemother. pmid:9593139
Spangler SK et al. Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. 1998 Antimicrob. Agents Chemother. pmid:9593160
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Kozyrskyj AL et al. Treatment of acute otitis media with a shortened course of antibiotics: a meta-analysis. 1998 JAMA pmid:9624028
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[6th München AIDS-Days. Azithromycin in HIV-associated opportunistic infections]. 1998 Internist (Berl) pmid:9648000
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Bass JW et al. Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. 1998 Pediatr. Infect. Dis. J. pmid:9655532
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Vcev A et al. Omeprazole, azithromycin and either amoxycillin or metronidazole in eradication of Helicobacter pylori in duodenal ulcer patients. 1998 Aliment. Pharmacol. Ther. pmid:9663725
Nash MM and Zaltzman JS Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. 1998 Transplantation pmid:9665078
Dooley DP Revisiting doxycycline. 1998 Arch. Intern. Med. pmid:9665360
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Wawer MJ et al. A randomized, community trial of intensive sexually transmitted disease control for AIDS prevention, Rakai, Uganda. 1998 AIDS pmid:9677171
Rapp RP Pharmacokinetics and pharmacodynamics of intravenous and oral azithromycin: enhanced tissue activity and minimal drug interactions. 1998 Jul-Aug Ann Pharmacother pmid:9681095
Zaremba CD Comment: could acetaminophen have played a role in a possible azithromycin-warfarin interaction? 1998 Jul-Aug Ann Pharmacother pmid:9681108
Turcinov T and Pepeljnjak S Azithromycin potency determination: optimal conditions for microbiological diffusion method assay. 1998 J Pharm Biomed Anal pmid:9682177
Soepandi P et al. The pattern of micro-organisms and the efficacy of new macrolide in acute lower respiratory tract infections. 1998 Respirology pmid:9692520
Blandizzi C et al. Gastric mucosal distribution and clinical efficacy of azithromycin in patients with Helicobacter pylori related gastritis. 1998 J. Antimicrob. Chemother. pmid:9700531
Cremer J et al. Azithromycin versus cefaclor in the treatment of pediatric patients with acute group A beta-hemolytic streptococcal tonsillopharyngitis. 1998 Eur. J. Clin. Microbiol. Infect. Dis. pmid:9707305
García Callejo FJ et al. [Comparison of azithromycin, amoxicillin/clavulanic acid and cefaclor in the treatment of acute ENT infections]. 1998 Acta Otorrinolaringol Esp pmid:9707742
Kober MB and Mason BA Colonization of the female genital tract by resistant Ureaplasma urealyticum treated successfully with azithromycin. 1998 Clin. Infect. Dis. pmid:9709898
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Bianchi A et al. Kinetics of Chlamydia trachomatis clearance in patients with azithromycin, as assessed by first void urine testing by PCR and transcription-mediated amplification. 1998 Sex Transm Dis pmid:9713917
Venuta A et al. Azithromycin compared with clarithromycin for the treatment of streptococcal pharyngitis in children. 1998 Jun-Jul J. Int. Med. Res. pmid:9718470
Haye R et al. Azithromycin versus placebo in acute infectious rhinitis with clinical symptoms but without radiological signs of maxillary sinusitis. 1998 Eur. J. Clin. Microbiol. Infect. Dis. pmid:9721958