Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rim JH et al. | Recent Increase in the Incidence of TEM-135 β-Lactamase-harboring Neisseria gonorrhoeae in Korea. | 2018 | Ann Lab Med | pmid:29611382 |
| Afghani T et al. | Preventing Long-Term Ocular Complications of Trachoma With Topical Azithromycin: A 3-Year Follow-up Study. | 2017 Jan-Feb | Asia Pac J Ophthalmol (Phila) | pmid:28161923 |
| González-Beiras C et al. | Single-Dose Azithromycin for the Treatment of Haemophilus ducreyi Skin Ulcers in Papua New Guinea. | 2017 | Clin. Infect. Dis. | pmid:29020192 |
| Lu Y et al. | Antibiotics Promote Escherichia coli-Pseudomonas aeruginosa Conjugation through Inhibiting Quorum Sensing. | 2017 | Antimicrob. Agents Chemother. | pmid:28993333 |
| Agarwal P et al. | susceptibility of Indian isolates to different antimalarial drugs & antibiotics. | 2017 | Indian J. Med. Res. | pmid:29512604 |
| Paul P et al. | Capillary electrophoresis with capacitively coupled contactless conductivity detection method development and validation for the determination of azithromycin, clarithromycin, and clindamycin. | 2017 | J Sep Sci | pmid:28683179 |
| Volgers C et al. | Budesonide, fluticasone propionate, and azithromycin do not modulate the membrane vesicle release by THP-1 macrophages and respiratory pathogens during macrophage infection. | 2017 | Inflammopharmacology | pmid:28528362 |
| Hoogewoud F et al. | Prognostic Factors in Syphilitic Uveitis. | 2017 | Ophthalmology | pmid:28779905 |
| Bloch EM et al. | Antibiotic Resistance in Young Children in Kilosa District, Tanzania 4 Years after Mass Distribution of Azithromycin for Trachoma Control. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28722638 |
| O'Brien KS et al. | Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28722569 |
| Stoney RJ et al. | Travelers' Diarrhea and Other Gastrointestinal Symptoms Among Boston-Area International Travelers. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28719282 |
| Harper LM et al. | Economic Evaluation of Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2017 | Obstet Gynecol | pmid:28697108 |
| Fan LC et al. | Macrolides protect against infection via inhibition of inflammasomes. | 2017 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:28684545 |
| Wang Y et al. | Synthesis and antibacterial activity of novel 4″-O-(1-aralkyl-1,2,3-triazol-4-methyl-carbamoyl) azithromycin analogs. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28655423 |
| Kirk SK et al. | Efficacy of Azithromycin and Compounded Atovaquone for Treatment of Babesia gibsoni in Dogs. | 2017 | J. Vet. Intern. Med. | pmid:28625019 |
| Vajpayee S et al. | Scrub typhus causing neonatal hepatitis with acute liver failure-A case series. | 2017 | Indian J Gastroenterol | pmid:28612320 |
| Kimura S et al. | Azithromycin Modulates 3',5'-cyclic Diguanylic Acid Signaling in Pseudomonas aeruginosa. | 2017 | J. Infect. Chemother. | pmid:28579350 |
| Dixit S et al. | Carbamoylated azithromycin incorporated zirconia hybrid monolith for enantioseparation of acidic chiral drugs using non-aqueous capillary electrochromatography. | 2017 | J Chromatogr A | pmid:28558906 |
| Jordan SJ et al. | Lower Levels of Cervicovaginal Tryptophan Are Associated With Natural Clearance of Chlamydia in Women. | 2017 | J. Infect. Dis. | pmid:28520912 |
| Lopes Dos Santos Santiago G et al. | Influence of chronic azithromycin treatment on the composition of the oropharyngeal microbial community in patients with severe asthma. | 2017 | BMC Microbiol. | pmid:28486933 |
| Savaris RF et al. | Antibiotic therapy for pelvic inflammatory disease. | 2017 | Cochrane Database Syst Rev | pmid:28436019 |
| Emmanuel R et al. | Antimicrobial efficacy of drug blended biosynthesized colloidal gold nanoparticles from Justicia glauca against oral pathogens: A nanoantibiotic approach. | 2017 | Microb. Pathog. | pmid:29101061 |
| Riddle MS et al. | Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. | 2017 | Clin. Infect. Dis. | pmid:29029033 |
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| Senilă S et al. | Infliximab-induced acne and acute localized exanthematous pustulosis: Case report. | 2017 | Dermatol Ther | pmid:28976720 |
| Giguère S et al. | Antimicrobial Resistance in . | 2017 | Microbiol Spectr | pmid:29052538 |
| Boggess KA et al. | Risk Factors for Postcesarean Maternal Infection in a Trial of Extended-Spectrum Antibiotic Prophylaxis. | 2017 | Obstet Gynecol | pmid:28178058 |
| Koeva M et al. | An Antipersister Strategy for Treatment of Chronic Pseudomonas aeruginosa Infections. | 2017 | Antimicrob. Agents Chemother. | pmid:28923873 |
| Ullah S et al. | Creatinine-based non-phospholipid vesicular carrier for improved oral bioavailability of Azithromycin. | 2017 | Drug Dev Ind Pharm | pmid:28157445 |
| Mohammed H et al. | First line dual therapy for gonorrhoea to limit the spread of antimicrobial resistance. | 2017 | BMJ | pmid:28153820 |
| Ito A et al. | A Case of Community-Acquired Pneumonia Due to Legionella pneumophila Serogroup 9 Wherein Initial Treatment with Single-Dose Oral Azithromycin Appeared Useful. | 2017 | Jpn. J. Infect. Dis. | pmid:28890505 |
| Oluwalana C et al. | Azithromycin in Labor Lowers Clinical Infections in Mothers and Newborns: A Double-Blind Trial. | 2017 | Pediatrics | pmid:28130432 |
| Saiz JC and MartÃn-Acebes MA | Reply to Iannetta et al., "Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells". | 2017 | Antimicrob. Agents Chemother. | pmid:28839084 |
| Gerber JS and Zaoutis TE | Azithromycin Prophylaxis for Laboring Mothers. | 2017 | Pediatrics | pmid:28130431 |
| Iannetta M et al. | Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells. | 2017 | Antimicrob. Agents Chemother. | pmid:28839081 |
| Cogen JD et al. | Characterization of Inpatient Cystic Fibrosis Pulmonary Exacerbations. | 2017 | Pediatrics | pmid:28126911 |
| Cramer CL et al. | Immunomodulatory indications of azithromycin in respiratory disease: a concise review for the clinician. | 2017 | Postgrad Med | pmid:28116959 |
| Liu D et al. | Mycoplasma-associated multidrug resistance of hepatocarcinoma cells requires the interaction of P37 and Annexin A2. | 2017 | PLoS ONE | pmid:28976984 |
| Lee S et al. | The therapeutic efficacy of azithromycin and nitazoxanide in the acute pig model of Cryptosporidium hominis. | 2017 | PLoS ONE | pmid:28973041 |
| Kibuule D et al. | An analysis of policies for cotrimoxazole, amoxicillin and azithromycin use in Namibia's public sector: Findings and therapeutic implications. | 2017 | Int. J. Clin. Pract. | pmid:28090718 |
| Lee SC et al. | Comparative effectiveness of azithromycin for treating scrub typhus: A PRISMA-compliant systematic review and meta-analysis. | 2017 | Medicine (Baltimore) | pmid:28885357 |
| Mandhane PJ et al. | Treatment of preschool children presenting to the emergency department with wheeze with azithromycin: A placebo-controlled randomized trial. | 2017 | PLoS ONE | pmid:28771627 |
| Okah E et al. | Sentinel Surveillance for Expedited Partner Therapy Prescriptions Using Pharmacy Data, in 2 New York City Neighborhoods, 2015. | 2017 | Sex Transm Dis | pmid:28079746 |
| Gifford J et al. | Decision support during electronic prescription to stem antibiotic overuse for acute respiratory infections: a long-term, quasi-experimental study. | 2017 | BMC Infect. Dis. | pmid:28760143 |
| Ragusa A and Svelato A | Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2017 | N. Engl. J. Med. | pmid:28079335 |
| Greig JR and Jones L | Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2017 | N. Engl. J. Med. | pmid:28079334 |
| Varano GP et al. | Post-ischemic treatment with azithromycin protects ganglion cells against retinal ischemia/reperfusion injury in the rat. | 2017 | Mol. Vis. | pmid:29296071 |
| Pokharel S et al. | Co-trimoxazole versus azithromycin for the treatment of undifferentiated febrile illness in Nepal: study protocol for a randomized controlled trial. | 2017 | Trials | pmid:28969659 |
| Brown JD et al. | Shigella species epidemiology and antimicrobial susceptibility: the implications of emerging azithromycin resistance for guiding treatment, guidelines and breakpoints. | 2017 | J. Antimicrob. Chemother. | pmid:28961759 |
| Jacobsson S et al. | Activity of the Novel Pleuromutilin Lefamulin (BC-3781) and Effect of Efflux Pump Inactivation on Multidrug-Resistant and Extensively Drug-Resistant Neisseria gonorrhoeae. | 2017 | Antimicrob. Agents Chemother. | pmid:28893785 |
| Sharpton R et al. | Do cystic fibrosis patients on azithromycin need electrocardiogram monitoring? | 2017 | Pulm Pharmacol Ther | pmid:28219728 |
| Tribble DR | Antibiotic Therapy for Acute Watery Diarrhea and Dysentery. | 2017 | Mil Med | pmid:28885920 |
| Braam JF et al. | High prevalence of the A2058T macrolide resistance-associated mutation in Mycoplasma genitalium strains from the Netherlands. | 2017 | J. Antimicrob. Chemother. | pmid:28158595 |
| Asano N et al. | Limited Azithromycin Localization to Rabbit Meibomian Glands Revealed by LC-MS-Based Bioanalysis and DESI Imaging. | 2017 | Biol. Pharm. Bull. | pmid:28867744 |
| Gensel JC et al. | Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment. | 2017 | Sci Rep | pmid:28057928 |
| Seyama S et al. | Amino Acid Substitution in the Major Multidrug Efflux Transporter Protein AcrB Contributes to Low Susceptibility to Azithromycin in Haemophilus influenzae. | 2017 | Antimicrob. Agents Chemother. | pmid:28848006 |
| Sutton SS | Is cardiovascular risk a concern when prescribing azithromycin? | 2017 | JAAPA | pmid:28033168 |
| Yoon HY et al. | Clinical significance of QT-prolonging drug use in patients with MDR-TB or NTM disease. | 2017 | Int. J. Tuberc. Lung Dis. | pmid:28826448 |
| Shapiro ED and Wormser GP | Prophylaxis with topical azithromycin against Lyme borreliosis. | 2017 | Lancet Infect Dis | pmid:28007427 |
| Seyama S et al. | Emergence and molecular characterization of Haemophilus influenzae harbouring mef(A). | 2017 | J. Antimicrob. Chemother. | pmid:27999037 |
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| Yan M et al. | Synthesis and antibacterial activity of novel 3-O-descladinosylazithromycin derivatives. | 2017 | Eur J Med Chem | pmid:27836198 |
| Ginouvès M et al. | In Vitro Sensitivity of Cutaneous Leishmania Promastigote Isolates Circulating in French Guiana to a Set of Drugs. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28167598 |
| Haque F et al. | Evaluation of a Smartphone Decision-Support Tool for Diarrheal Disease Management in a Resource-Limited Setting. | 2017 | PLoS Negl Trop Dis | pmid:28103233 |
| Chavada VD et al. | Surface plasmon resonance based selective and sensitive colorimetric determination of azithromycin using unmodified silver nanoparticles in pharmaceuticals and human plasma. | 2017 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:27419643 |
| Bulman ZP et al. | Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin. | 2017 | Antimicrob. Agents Chemother. | pmid:28096154 |
| Wind CM et al. | Trends in antimicrobial susceptibility for azithromycin and ceftriaxone in Neisseria gonorrhoeae isolates in Amsterdam, the Netherlands, between 2012 and 2015. | 2017 | Euro Surveill. | pmid:28079519 |
| Agarwal E et al. | Locally Delivered 0.5% Azithromycin as an Adjunct to Non-Surgical Treatment in Patients With Chronic Periodontitis With Type 2 Diabetes: A Randomized Controlled Clinical Trial. | 2017 | J. Periodontol. | pmid:22655911 |
| Tita ATN et al. | Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2017 | N. Engl. J. Med. | pmid:28076707 |
| Idkaidek N et al. | Saliva Versus Plasma Bioequivalence of Azithromycin in Humans: Validation of Class I Drugs of the Salivary Excretion Classification System. | 2017 | Drugs R D | pmid:28074334 |
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| Gomes C et al. | Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin. | 2017 | Crit. Rev. Microbiol. | pmid:27786586 |
| Kwakye-Maclean C et al. | A Single Dose Oral Azithromycin versus Intramuscular Benzathine Penicillin for the Treatment of Yaws-A Randomized Non Inferiority Trial in Ghana. | 2017 | PLoS Negl Trop Dis | pmid:28072863 |
| Fu L et al. | Toxicity of 13 different antibiotics towards freshwater green algae Pseudokirchneriella subcapitata and their modes of action. | 2017 | Chemosphere | pmid:27783962 |
| Descours G et al. | Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila. | 2017 | Antimicrob. Agents Chemother. | pmid:28069647 |
| Lau A et al. | Treatment efficacy of azithromycin 1Â g single dose versus doxycycline 100Â mg twice daily for 7Â days for the treatment of rectal chlamydia among men who have sex with men - a double-blind randomised controlled trial protocol. | 2017 | BMC Infect. Dis. | pmid:28061753 |
| Saini H et al. | Azithromycin-Ciprofloxacin-Impregnated Urinary Catheters Avert Bacterial Colonization, Biofilm Formation, and Inflammation in a Murine Model of Foreign-Body-Associated Urinary Tract Infections Caused by Pseudomonas aeruginosa. | 2017 | Antimicrob. Agents Chemother. | pmid:28031194 |
| Björnelius E et al. | macrolide resistance in Stockholm, Sweden. | 2017 | Sex Transm Infect | pmid:27502694 |
| O'Rourke VJ | Azithromycin as an adjunct to non-surgical periodontal therapy: a systematic review. | 2017 | Aust Dent J | pmid:27492140 |
| Illia R et al. | Role of cervical cerclage and prolonged antibiotic therapy with azithromycin in patients with previous perinatal loss amnionitis. | 2017 | J. Matern. Fetal. Neonatal. Med. | pmid:27094535 |
| Massip C et al. | Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump. | 2017 | J. Antimicrob. Chemother. | pmid:28137939 |
| Srivastava S et al. | Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance. | 2017 | J. Antimicrob. Chemother. | pmid:28922805 |
| Cole MJ et al. | Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015. | 2017 | BMC Infect. Dis. | pmid:28893203 |
| Xue Y et al. | An in vitro model of azithromycin-induced persistent Chlamydia trachomatis infection. | 2017 | FEMS Microbiol. Lett. | pmid:28854672 |
| Barberá MJ et al. | Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance: Prevalence and Risk Factors Among a 2013-2014 Cohort of Patients in Barcelona, Spain. | 2017 | Sex Transm Dis | pmid:28703723 |
| Brusselle G and Pavord I | Azithromycin in uncontrolled asthma. | 2017 | Lancet | pmid:28687412 |
| Xiao Z et al. | Comparison of the ameliorative effects of Qingfei Tongluo formula and azithromycin on Mycoplasma pneumoniae pneumonia. | 2017 | J Nat Med | pmid:28664473 |
| Atkinson CT et al. | Expression of acquired macrolide resistance genes in Haemophilus influenzae. | 2017 | J. Antimicrob. Chemother. | pmid:28961896 |
| Lendermon EA et al. | Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation. | 2017 | Respir. Res. | pmid:28659178 |
| Turner KM et al. | Analysis of the potential for point-of-care test to enable individualised treatment of infections caused by antimicrobial-resistant and susceptible strains of : a modelling study. | 2017 | BMJ Open | pmid:28615273 |
| Katz AR et al. | Cluster of Neisseria gonorrhoeae Isolates With High-level Azithromycin Resistance and Decreased Ceftriaxone Susceptibility, Hawaii, 2016. | 2017 | Clin. Infect. Dis. | pmid:28549097 |
| Lee N et al. | Anti-inflammatory effects of adjunctive macrolide treatment in adults hospitalized with influenza: A randomized controlled trial. | 2017 | Antiviral Res. | pmid:28535933 |
| Allen GP and Harris KA | Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin. | 2017 | Antimicrob. Agents Chemother. | pmid:28483960 |
| Fohner AE et al. | PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. | 2017 | Pharmacogenet. Genomics | pmid:28146011 |
| Koop AH et al. | 56-Year-Old Woman With Cough and Fatigue for 1 Week. | 2017 | Mayo Clin. Proc. | pmid:28110893 |
| Murray K et al. | Increasing Antibiotic Resistance in Shigella spp. from Infected New York City Residents, New York, USA. | 2017 | Emerging Infect. Dis. | pmid:28098543 |
| Nichols DP et al. | Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis. | 2017 | J. Cyst. Fibros. | pmid:28025037 |
| Marks M et al. | Mathematical Modeling of Programmatic Requirements for Yaws Eradication. | 2017 | Emerging Infect. Dis. | pmid:27983500 |
| Zhang C et al. | Decreased Susceptibility to Azithromycin Among Clinical Shigella Isolates from China. | 2017 | Microb. Drug Resist. | pmid:27841958 |
| Segal LN et al. | Randomised, double-blind, placebo-controlled trial with azithromycin selects for anti-inflammatory microbial metabolites in the emphysematous lung. | 2017 | Thorax | pmid:27486204 |