Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Urinary Tract Infections D014552 11 associated lipids
Urticaria D014581 13 associated lipids
Vertigo D014717 4 associated lipids
Vomiting D014839 21 associated lipids
Whooping Cough D014917 6 associated lipids
Wound Infection D014946 12 associated lipids
Yaws D015001 4 associated lipids
Superinfection D015163 3 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Corneal Edema D015715 3 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Pelvic Pain D017699 7 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Furcation Defects D017823 1 associated lipids
T-Lymphocytopenia, Idiopathic CD4-Positive D018344 1 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Parasitemia D018512 5 associated lipids
Abdominal Abscess D018784 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Pseudolymphoma D019310 1 associated lipids
Pouchitis D019449 3 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Mucositis D052016 7 associated lipids
Tendinopathy D052256 3 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Pyomyositis D052880 2 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Acute Lung Injury D055371 33 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Neglected Diseases D058069 3 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Trichiasis D058457 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Tick Bites D064927 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Wynn RF et al. Azithromycin for cerebral toxoplasmosis in AIDS. 1993 Lancet pmid:8093526
Fortner JH et al. Tapetal effect of an azalide antibiotic following oral administration in beagle dogs. 1993 Fundam Appl Toxicol pmid:8405779
Bailey RL et al. Randomised controlled trial of single-dose azithromycin in treatment of trachoma. 1993 Lancet pmid:8102427
Narcio Reyes LE et al. [Efficacy and safety of azithromycin in the treatment of female genital Chlamydia trachomatis infections]. 1993 Ginecol Obstet Mex pmid:8406112
Donowitz GR and Earnhardt KI Azithromycin inhibition of intracellular Legionella micdadei. 1993 Antimicrob. Agents Chemother. pmid:8285604
Vaara M Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. 1993 Antimicrob. Agents Chemother. pmid:8383945
Brown ST et al. Azithromycin, rifabutin, and rifapentine for treatment and prophylaxis of Mycobacterium avium complex in rats treated with cyclosporine. 1993 Antimicrob. Agents Chemother. pmid:8384809
Cameron DJ Effectiveness of early Lyme disease treatment. 1993 Am. J. Med. pmid:8388627
Hammerschlag MR et al. Single dose of azithromycin for the treatment of genital chlamydial infections in adolescents. 1993 J. Pediatr. pmid:8388950
Melski JW et al. Primary and secondary erythema migrans in central Wisconsin. 1993 Arch Dermatol pmid:8389536
Kobrehel G et al. 9a,11-cyclic carbamates of 15-membered azalides. 1993 J. Antibiot. pmid:8407586
Bonnet M and Van der Auwera P Preincubation of Haemophilus influenzae with subinhibitory concentrations of macrolides: influence on human neutrophil chemiluminescence. 1993 Antimicrob. Agents Chemother. pmid:8390808
Gordillo ME et al. In vitro activity of azithromycin against bacterial enteric pathogens. 1993 Antimicrob. Agents Chemother. pmid:8390813
Blais J et al. Inhibition of Toxoplasma gondii protein synthesis by azithromycin. 1993 Antimicrob. Agents Chemother. pmid:8215287
Dever LL et al. Comparative in vitro activities of clarithromycin, azithromycin, and erythromycin against Borrelia burgdorferi. 1993 Antimicrob. Agents Chemother. pmid:8215288
Heifets L et al. Mycobacterium avium strains resistant to clarithromycin and azithromycin. 1993 Antimicrob. Agents Chemother. pmid:8031351
Fass RJ Erythromycin, clarithromycin, and azithromycin: use of frequency distribution curves, scattergrams, and regression analyses to compare in vitro activities and describe cross-resistance. 1993 Antimicrob. Agents Chemother. pmid:8257127
Gomberg MA and MashkilleÄ­son AL [Use of azithromycin in long existing urogenital chlamydia infections and its association with primary syphilis]. 1993 Antibiot. Khimioter. pmid:8060178
Lopatkin NA et al. [Use of azithromycin ("Sumamded") in the treatment of infectious-inflammatory diseases of the lower urinary tract and male genitalia]. 1993 Antibiot. Khimioter. pmid:8060189
Saba J et al. Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. 1993 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8112357
Weiss LM et al. Efficacy of azithromycin for treating Babesia microti infection in the hamster model. 1993 J. Infect. Dis. pmid:8228366
Lefèvre JC et al. In vitro evaluation of activities of azithromycin, clarithromycin and sparfloxacin against Chlamydia trachomatis. 1993 Pathol. Biol. pmid:8233628
Agacfidan A et al. In vitro activity of azithromycin (CP-62,993) against Chlamydia trachomatis and Chlamydia pneumoniae. 1993 Antimicrob. Agents Chemother. pmid:8239579
Tomazic J et al. In vivo administration of azithromycin affects lymphocyte activity in vitro. 1993 Antimicrob. Agents Chemother. pmid:8239585
Cantin L and Chamberland S In vitro evaluation of the activities of azithromycin alone and combined with pyrimethamine against Toxoplasma gondii. 1993 Antimicrob. Agents Chemother. pmid:8239619
Meyer AP et al. Uptake of azithromycin by human monocytes and enhanced intracellular antibacterial activity against Staphylococcus aureus. 1993 Antimicrob. Agents Chemother. pmid:8285612
Lalak NJ and Morris DL Azithromycin clinical pharmacokinetics. 1993 Clin Pharmacokinet pmid:8287632
Saverino D et al. Plasmid loss from gram-negative bacteria exposed to subinhibitory concentrations of beta-lactam drugs and azithromycin. 1993 New Microbiol. pmid:8264424
Pajukanta R In vitro antimicrobial susceptibility of Porphyromonas gingivalis to azithromycin, a novel macrolide. 1993 Oral Microbiol. Immunol. pmid:8265209
Gage TW New drugs from 1991-1992. 1993 Tex Dent J pmid:8273018
Holdcroft C Two new macrolide antibiotics: clarithromycin and azithromycin. 1993 Nurse Pract pmid:8380492
Rodewald LE and Pichichero ME Compliance with antibiotic therapy: a comparison of deuterium oxide tracer, urine bioassay, bottle weights, and parental reports. 1993 J. Pediatr. pmid:8391566
de Górgolas Hernández-Mora M et al. [Therapeutic approaches to cryptosporidiosis. A review of the literature]. 1993 Rev Clin Esp pmid:8259458
Vargas SL et al. Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancer. 1993 J. Pediatr. pmid:8391567
Berger BW Lyme disease. 1993 Semin Dermatol pmid:8312152
O'Connell S et al. Chronic active toxoplasmosis in an immunocompetent patient. 1993 J. Infect. pmid:8308325
Gingras BA and Jensen JB Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. 1993 Am. J. Trop. Med. Hyg. pmid:8394660
Mansoor GA et al. Azithromycin-induced acute interstitial nephritis. 1993 Ann. Intern. Med. pmid:8395778
Guerra LG et al. Rapid response of AIDS-related bacillary angiomatosis to azithromycin. 1993 Clin. Infect. Dis. pmid:8399879
Workowski KA et al. Azithromycin in chlamydial urethritis. 1993 JAMA pmid:8411548
Díaz Sánchez M et al. [New medications: azithromycin]. 1993 Jul-Sep Rev Med Univ Navarra pmid:8134755
Odugbemi T et al. Single oral dose of azithromycin for therapy of susceptible sexually transmitted diseases: a multicenter open evaluation. 1993 Jul-Sep West Afr J Med pmid:8312208
Minguez F et al. In vitro killing kinetics and postantibiotic effect of josamycin and other macrolides on several bacteria. 1993 May-Jun Chemotherapy pmid:8389685
Weber K et al. Azithromycin versus penicillin V for the treatment of early Lyme borreliosis. 1993 Nov-Dec Infection pmid:8132365
Scaglione F et al. A new model examining intracellular and extracellular activity of amoxicillin, azithromycin, and clarithromycin in infected cells. 1993 Nov-Dec Chemotherapy pmid:8222870
Braga PC and Piatti G Interference by subinhibitory concentrations of azithromycin with the mechanism of bacterial adhesion to human epithelial cells. 1993 Nov-Dec Chemotherapy pmid:8222872
Goldman MP and Longworth DL The role of azithromycin and clarithromycin in clinical practice. 1993 Sep-Oct Cleve Clin J Med pmid:8403355
Steven N et al. Corticosteroid therapy for AIDS patients with Mycobacterium avium-intracellulare infection. 1994 AIDS pmid:8011231
Chiarini F et al. Chlamydia trachomatis genitourinary infections: laboratory diagnosis and therapeutic aspects. Evaluation of in vitro and in vivo effectiveness of azithromycin. 1994 J Chemother pmid:7830100
[Newly approved specialty drugs in Austria and new knowledge about currently available specialty drugs. Zithromax capsules, dried syrup]. 1994 Wien. Klin. Wochenschr. pmid:7975673