Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Urinary Tract Infections D014552 11 associated lipids
Urticaria D014581 13 associated lipids
Vertigo D014717 4 associated lipids
Vomiting D014839 21 associated lipids
Whooping Cough D014917 6 associated lipids
Wound Infection D014946 12 associated lipids
Yaws D015001 4 associated lipids
Superinfection D015163 3 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Corneal Edema D015715 3 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Pelvic Pain D017699 7 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Furcation Defects D017823 1 associated lipids
T-Lymphocytopenia, Idiopathic CD4-Positive D018344 1 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Parasitemia D018512 5 associated lipids
Abdominal Abscess D018784 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Pseudolymphoma D019310 1 associated lipids
Pouchitis D019449 3 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Mucositis D052016 7 associated lipids
Tendinopathy D052256 3 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Pyomyositis D052880 2 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Acute Lung Injury D055371 33 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Neglected Diseases D058069 3 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Trichiasis D058457 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Tick Bites D064927 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Mabey D Azithromycin resistance in Treponema pallidum. 2009 Sex Transm Dis pmid:19801961
Hublikar S et al. Disseminated gonococcal infection and eculizumab--a "high risk" connection? 2014 Sex Transm Dis pmid:25581812
Cole MJ et al. Risk factors for antimicrobial-resistant Neisseria gonorrhoeae in Europe. 2014 Sex Transm Dis pmid:25581808
Zhou P et al. Occurrence of congenital syphilis after maternal treatment with azithromycin during pregnancy. 2007 Sex Transm Dis pmid:17589329
Thakur SD et al. Resistance to Ceftriaxone and Azithromycin in Neisseria gonorrhoeae Isolates From 7 Countries of South America and the Caribbean: 2010-2011. 2017 Sex Transm Dis pmid:28178114
Yasin RM et al. Comparison of E-test with agar dilution methods in testing susceptibility of N. gonorrhoeae to azithromycin. 1997 Sex Transm Dis pmid:9153733
Hook EW et al. A randomized, comparative pilot study of azithromycin versus benzathine penicillin G for treatment of early syphilis. 2002 Sex Transm Dis pmid:12172535
Beymer MR et al. Evaluation of gonorrhea test of cure at 1 week in a Los Angeles community-based clinic serving men who have sex with men. 2014 Sex Transm Dis pmid:25211254
Tyndall MW et al. Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. 1994 Jul-Aug Sex Transm Dis pmid:7974076
Holman KM et al. Rapid plasma reagin titer variation in the 2 weeks after syphilis therapy. 2012 Sex Transm Dis pmid:22801348
Martin IE et al. Molecular typing of Treponema pallidum strains in western Canada: predominance of 14d subtypes. 2010 Sex Transm Dis pmid:20539263
Molini BJ et al. Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains. 2016 Sex Transm Dis pmid:27513385
Xiridou M et al. Cost-Effectiveness of Dual Antimicrobial Therapy for Gonococcal Infections Among Men Who Have Sex With Men in the Netherlands. 2016 Sex Transm Dis pmid:27513379
Lázaro MJ et al. A case of late-stage lymphogranuloma venereum in a woman in Europe. 2013 Sex Transm Dis pmid:24275729
Abdolrasouli A and Roushan A Corynebacterium propinquum associated with acute, nongonococcal urethritis. 2013 Sex Transm Dis pmid:24275738
Manhart LE Has the time come to systematically test for Mycoplasma genitalium? 2009 Sex Transm Dis pmid:19734818
Noda AA et al. First Report of the 23S rRNA Gene A2058G Point Mutation Associated With Macrolide Resistance in Treponema pallidum From Syphilis Patients in Cuba. 2016 Sex Transm Dis pmid:27100771
Galarza PG et al. Emergence of high level azithromycin-resistant Neisseria gonorrhoeae strain isolated in Argentina. 2009 Sex Transm Dis pmid:19734823
Gratrix J et al. Retrospective review of pharyngeal gonorrhea treatment failures in Alberta, Canada. 2013 Sex Transm Dis pmid:24113412
Haddix AC et al. The cost effectiveness of azithromycin for Chlamydia trachomatis infections in women. 1995 Sep-Oct Sex Transm Dis pmid:7502180
Gratrix J et al. A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men. 2016 Sex Transm Dis pmid:26760180
Steen R et al. Evidence of declining STD prevalence in a South African mining community following a core-group intervention. 2000 Sex Transm Dis pmid:10654860
Boix V et al. Polyostotic osteitis in secondary syphilis in an HIV-infected patient. 2013 Sex Transm Dis pmid:23859912
Khosropour CM et al. Comparing azithromycin and doxycycline for the treatment of rectal chlamydial infection: a retrospective cohort study. 2014 Sex Transm Dis pmid:24413484
Jordan SJ and Geisler WM Azithromycin for rectal chlamydia: is it time to leave azithromycin on the shelf?...Not yet. 2014 Sex Transm Dis pmid:24413485
Horner P et al. Which azithromycin regimen should be used for treating ? A meta-analysis. 2018 Sex Transm Infect pmid:28717050
Niccolai LM et al. Behavioural sources of repeat Chlamydia trachomatis infections: importance of different sex partners. 2011 Sex Transm Infect pmid:21212380
Khosropour CM et al. Efficacy of standard therapies against Ureaplasma species and persistence among men with non-gonococcal urethritis enrolled in a randomised controlled trial. 2015 Sex Transm Infect pmid:25616607
Magbanua JP et al. Chlamydia trachomatis variant not detected by plasmid based nucleic acid amplification tests: molecular characterisation and failure of single dose azithromycin. 2007 Sex Transm Infect pmid:17567684
Bignell C and Garley J Azithromycin in the treatment of infection with Neisseria gonorrhoeae. 2010 Sex Transm Infect pmid:20940153
Downing J et al. Management of cases testing positive for gonococcal infection in a community-based chlamydia screening programme. 2010 Sex Transm Infect pmid:20940161
Gundevia Z et al. Positivity at test of cure following first-line treatment for genital Mycoplasma genitalium: follow-up of a clinical cohort. 2015 Sex Transm Infect pmid:25096921
National guideline for the management of donovanosis (granuloma inguinale). Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). 1999 Sex Transm Infect pmid:10616381
Pasternack R et al. Follow up of treatment: an integral part of the control of Chlamydia trachomatis infections. 1999 Sex Transm Infect pmid:10448353
Cabeza J et al. Feasibility of Chlamydia trachomatis screening and treatment in pregnant women in Lima, Peru: a prospective study in two large urban hospitals. 2015 Sex Transm Infect pmid:25107711
Romoren M et al. Costs and health consequences of chlamydia management strategies among pregnant women in sub-Saharan Africa. 2007 Sex Transm Infect pmid:17932126
Domeika M et al. Chlamydia trachomatis infections in eastern Europe: legal aspects, epidemiology, diagnosis, and treatment. 2002 Sex Transm Infect pmid:12081171
Patrick DM et al. Heterosexual outbreak of infectious syphilis: epidemiological and ethnographic analysis and implications for control. 2002 Sex Transm Infect pmid:12083438
Thompson C Azithromycin v oxytetracycline for the treatment of non-specific urethritis. 2000 Sex Transm Infect pmid:10961211
Hathorn E et al. What is the most appropriate treatment for rectal Chlamydia trachomatis infection? 2016 Sex Transm Infect pmid:26892930
Hathorn E et al. What is the appropriate treatment for the management of rectal Chlamydia trachomatis in men and women? 2012 Sex Transm Infect pmid:22517887
Murray S and Marshall L Empiric NSU treatment needs updating. 2014 Sex Transm Infect pmid:25028712
Oud EV et al. Pitfalls in the diagnosis and management of inguinal lymphogranuloma venereum: important lessons from a case series. 2014 Sex Transm Infect pmid:24787368
Chisholm SA et al. An outbreak of high-level azithromycin resistant Neisseria gonorrhoeae in England. 2016 Sex Transm Infect pmid:26601852
Thakur SD et al. Molecular epidemiology of Neisseria gonorrhoeae isolates from Saskatchewan, Canada: utility of NG-MAST in predicting antimicrobial susceptibility regionally. 2014 Sex Transm Infect pmid:24503900
Khosropour CM et al. Suboptimal adherence to doxycycline and treatment outcomes among men with non-gonococcal urethritis: a prospective cohort study. 2014 Sex Transm Infect pmid:24106340
Björnelius E et al. Antibiotic treatment of symptomatic Mycoplasma genitalium infection in Scandinavia: a controlled clinical trial. 2008 Sex Transm Infect pmid:17932127
Horner P and Saunders J Should azithromycin 1 g be abandoned as a treatment for bacterial STIs? The case for and against. 2017 Sex Transm Infect pmid:27418572
Carter N and Horner P Treatment regimens in non-gonococcal urethritis. 2015 Sex Transm Infect pmid:25990780
Horner P The case for further treatment studies of uncomplicated genital Chlamydia trachomatis infection. 2006 Sex Transm Infect pmid:16877590