Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Bignell C and Garley J | Azithromycin in the treatment of infection with Neisseria gonorrhoeae. | 2010 | Sex Transm Infect | pmid:20940153 |
Downing J et al. | Management of cases testing positive for gonococcal infection in a community-based chlamydia screening programme. | 2010 | Sex Transm Infect | pmid:20940161 |
Gundevia Z et al. | Positivity at test of cure following first-line treatment for genital Mycoplasma genitalium: follow-up of a clinical cohort. | 2015 | Sex Transm Infect | pmid:25096921 |
National guideline for the management of donovanosis (granuloma inguinale). Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616381 | |
Pasternack R et al. | Follow up of treatment: an integral part of the control of Chlamydia trachomatis infections. | 1999 | Sex Transm Infect | pmid:10448353 |
Cabeza J et al. | Feasibility of Chlamydia trachomatis screening and treatment in pregnant women in Lima, Peru: a prospective study in two large urban hospitals. | 2015 | Sex Transm Infect | pmid:25107711 |
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Hathorn E et al. | What is the appropriate treatment for the management of rectal Chlamydia trachomatis in men and women? | 2012 | Sex Transm Infect | pmid:22517887 |
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Oud EV et al. | Pitfalls in the diagnosis and management of inguinal lymphogranuloma venereum: important lessons from a case series. | 2014 | Sex Transm Infect | pmid:24787368 |
Chisholm SA et al. | An outbreak of high-level azithromycin resistant Neisseria gonorrhoeae in England. | 2016 | Sex Transm Infect | pmid:26601852 |
Thakur SD et al. | Molecular epidemiology of Neisseria gonorrhoeae isolates from Saskatchewan, Canada: utility of NG-MAST in predicting antimicrobial susceptibility regionally. | 2014 | Sex Transm Infect | pmid:24503900 |
Khosropour CM et al. | Suboptimal adherence to doxycycline and treatment outcomes among men with non-gonococcal urethritis: a prospective cohort study. | 2014 | Sex Transm Infect | pmid:24106340 |
Björnelius E et al. | Antibiotic treatment of symptomatic Mycoplasma genitalium infection in Scandinavia: a controlled clinical trial. | 2008 | Sex Transm Infect | pmid:17932127 |
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Horner P | The case for further treatment studies of uncomplicated genital Chlamydia trachomatis infection. | 2006 | Sex Transm Infect | pmid:16877590 |