Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bin Abdulhak AA et al. | Azithromycin and Risk of Cardiovascular Death: A Meta-Analytic Review of Observational Studies. | Am J Ther | pmid:25748818 | |
| Veskitkul J et al. | Recurrent Acute Rhinosinusitis Prevention by Azithromycin in Children with Nonallergic Rhinitis. | J Allergy Clin Immunol Pract | pmid:28438539 | |
| Requena-Méndez A et al. | Enteric fever in Barcelona: Changing patterns of importation and antibiotic resistance. | Travel Med Infect Dis | pmid:27890811 | |
| Johnson P | Management of a 16-Year-Old With Axillary Lymphadenopathy: The Cat's in the Bag. | J Pediatr Health Care | pmid:27742481 | |
| Abdus-Salam RA et al. | A comparative study of azithromycin and sulphadoxine-pyrimethamine as prophylaxis against malaria in pregnancy. | Niger Postgrad Med J | pmid:27424614 | |
| El Hennawi DED et al. | Management of recurrent tonsillitis in children. | Am J Otolaryngol | pmid:28385329 | |
| MartÃn-Pozo A et al. | [Susceptibility to azithromycin and other antibiotics in recent isolates of Salmonella, Shigella and Yersinia]. | Enferm. Infecc. Microbiol. Clin. | pmid:24698008 | |
| Maniakas A and Desrosiers M | Azithromycin add-on therapy in high-risk postendoscopic sinus surgery patients failing corticosteroid irrigations: A clinical practice audit. | Am J Rhinol Allergy | pmid:24598145 | |
| Poizeau F et al. | [Shifting cellulitis in a patient with X-linked hypogammaglobulinemia]. | Ann Dermatol Venereol | pmid:27080822 | |
| Seguà DÃaz M | [What is the best treatment for urogenital Chlamydia trachomatis infection?] | Semergen | pmid:27068255 | |
| Ruiz Rebollo ML et al. | [Drug-induced acute pancreatitis]. | Gastroenterol Hepatol | pmid:26839206 | |
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| Amali A et al. | Long-term postoperative azithromycin in patients with chronic rhinosinusitis: A randomized clinical trial. | Am J Rhinol Allergy | pmid:26637580 | |
| pmid:21439162 | ||||
| Osman EY et al. | Analysis of Azithromycin Monohydrate as a Single or a Combinatorial Therapy in a Mouse Model of Severe Spinal Muscular Atrophy. | J Neuromuscul Dis | pmid:28598854 | |
| Dave J et al. | Trends in antibiotic susceptibility of enteric fever isolates in East London. | Travel Med Infect Dis | pmid:25964222 | |
| Sharma P et al. | Changing trends of culture-positive typhoid fever and antimicrobial susceptibility in a tertiary care North Indian Hospital over the last decade. | Indian J Med Microbiol | pmid:29735830 | |
| Singh M et al. | Sunray appearance in lacrimal canaliculitis. | Indian J Pathol Microbiol | pmid:29676385 | |
| Retsema J et al. | Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms. | 1987 | Antimicrob. Agents Chemother. | pmid:2449865 |
| Girard AE et al. | Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with an extended half-life and excellent tissue distribution. | 1987 | Antimicrob. Agents Chemother. | pmid:2830841 |
| Walsh M et al. | In vitro evaluation of CP-62,993, erythromycin, clindamycin, and tetracycline against Chlamydia trachomatis. | 1987 | Antimicrob. Agents Chemother. | pmid:3038010 |
| Chang HR and Pechère JC | In vitro effects of four macrolides (roxithromycin, spiramycin, azithromycin [CP-62,993], and A-56268) on Toxoplasma gondii. | 1988 | Antimicrob. Agents Chemother. | pmid:2837140 |
| Bermudez LE and Young LS | Activities of amikacin, roxithromycin, and azithromycin alone or in combination with tumor necrosis factor against Mycobacterium avium complex. | 1988 | Antimicrob. Agents Chemother. | pmid:2847644 |
| Chan KH et al. | Efficacy of a new macrolide (azithromycin). For acute otitis media in the chinchilla model. | 1988 | Arch. Otolaryngol. Head Neck Surg. | pmid:2844210 |
| Barry AL et al. | In vitro activities of azithromycin (CP 62,993), clarithromycin (A-56268; TE-031), erythromycin, roxithromycin, and clindamycin. | 1988 | Antimicrob. Agents Chemother. | pmid:2840016 |
| Araujo FG et al. | Azithromycin, a macrolide antibiotic with potent activity against Toxoplasma gondii. | 1988 | Antimicrob. Agents Chemother. | pmid:2840017 |
| Yourassowsky E et al. | Rate of bactericidal activity for Branhamella catarrhalis of a new macrolide, CP-62,993, compared with that of amoxicillin-clavulanic acid. | 1988 | Chemotherapy | pmid:2843324 |
| Ravdin JI and Skilogiannis J | In vitro susceptibilities of Entamoeba histolytica to azithromycin, CP-63,956, erythromycin, and metronidazole. | 1989 | Antimicrob. Agents Chemother. | pmid:2548442 |
| Gladue RP et al. | In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells: possible mechanism of delivery and release at sites of infection. | 1989 | Antimicrob. Agents Chemother. | pmid:2543276 |
| Goldman RC et al. | Role of protonated and neutral forms of macrolides in binding to ribosomes from gram-positive and gram-negative bacteria. | 1990 | Antimicrob. Agents Chemother. | pmid:2159256 |
| Gladue RP and Snider ME | Intracellular accumulation of azithromycin by cultured human fibroblasts. | 1990 | Antimicrob. Agents Chemother. | pmid:2168141 |
| Capobianco JO and Goldman RC | Erythromycin and azithromycin transport into Haemophilus influenzae ATCC 19418 under conditions of depressed proton motive force (delta mu H). | 1990 | Antimicrob. Agents Chemother. | pmid:2178338 |
| Gorby GL and McGee ZA | Antimicrobial interference with bacterial mechanisms of pathogenicity: effect of sub-MIC azithromycin on gonococcal piliation and attachment to human epithelial cells. | 1990 | Antimicrob. Agents Chemother. | pmid:1982402 |
| Goldman RC and Capobianco JO | Role of an energy-dependent efflux pump in plasmid pNE24-mediated resistance to 14- and 15-membered macrolides in Staphylococcus epidermidis. | 1990 | Antimicrob. Agents Chemother. | pmid:1963291 |
| Børsum T et al. | Chlamydia trachomatis: in vitro susceptibility of genital and ocular isolates to some quinolones, amoxicillin and azithromycin. | 1990 | Chemotherapy | pmid:1963393 |
| Pascual A et al. | Effect of azithromycin, roxithromycin and erythromycin on human polymorphonuclear leukocyte function against Staphylococcus aureus. | 1990 | Chemotherapy | pmid:1963394 |
| Bermudez LE et al. | Stimulation with cytokines enhances penetration of azithromycin into human macrophages. | 1991 | Antimicrob. Agents Chemother. | pmid:1667256 |
| Moellering RC | Introduction: revolutionary changes in the macrolide and azalide antibiotics. | 1991 | Am. J. Med. | pmid:1656735 |
| Casiano RR | Azithromycin and amoxicillin in the treatment of acute maxillary sinusitis. | 1991 | Am. J. Med. | pmid:1656739 |
| Dark D | Multicenter evaluation of azithromycin and cefaclor in acute lower respiratory tract infections. | 1991 | Am. J. Med. | pmid:1656740 |
| Mallory SB | Azithromycin compared with cephalexin in the treatment of skin and skin structure infections. | 1991 | Am. J. Med. | pmid:1656741 |
| Hopkins S | Clinical toleration and safety of azithromycin. | 1991 | Am. J. Med. | pmid:1656742 |
| Schentag JJ and Ballow CH | Tissue-directed pharmacokinetics. | 1991 | Am. J. Med. | pmid:1656743 |
| Azoulay-Dupuis E et al. | Prophylactic and therapeutic activities of azithromycin in a mouse model of pneumococcal pneumonia. | 1991 | Antimicrob. Agents Chemother. | pmid:1656849 |
| Amacher DE et al. | Comparison of the effects of the new azalide antibiotic, azithromycin, and erythromycin estolate on rat liver cytochrome P-450. | 1991 | Antimicrob. Agents Chemother. | pmid:1656856 |
| Perronne C et al. | Activities of sparfloxacin, azithromycin, temafloxacin, and rifapentine compared with that of clarithromycin against multiplication of Mycobacterium avium complex within human macrophages. | 1991 | Antimicrob. Agents Chemother. | pmid:1656860 |
| Araujo FG and Remington JS | Synergistic activity of azithromycin and gamma interferon in murine toxoplasmosis. | 1991 | Antimicrob. Agents Chemother. | pmid:1656872 |
| Davila D et al. | Pharmacokinetics of azithromycin after single oral dosing of experimental animals. | 1991 | Biopharm Drug Dispos | pmid:1657238 |
| Taylor DE and Chang N | In vitro susceptibilities of Campylobacter jejuni and Campylobacter coli to azithromycin and erythromycin. | 1991 | Antimicrob. Agents Chemother. | pmid:1659309 |
| Gelber RH et al. | Activities of various macrolide antibiotics against Mycobacterium leprae infection in mice. | 1991 | Antimicrob. Agents Chemother. | pmid:1648889 |