Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Moshkani SK and Dalimi A | Evaluation of the efficacy of atovaquone alone or in combination with azithromycin against acute murine toxoplasmosis. | 2000 | Vet. Res. Commun. | pmid:10836275 |
Matute AJ et al. | Is a 5 day course of azithromycin enough for infections caused by Legionella pneumophila? | 2000 | J. Antimicrob. Chemother. | pmid:10837459 |
Anderson JL and Muhlestein JB | The ACADEMIC study in perspective (Azithromycin in coronary artery disease: elimination of myocardial infection with Chlamydia). | 2000 | J. Infect. Dis. | pmid:10839761 |
Dunne MW | Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trial. | 2000 | J. Infect. Dis. | pmid:10839762 |
Jackson LA | Description and status of the azithromycin and coronary events study (ACES). | 2000 | J. Infect. Dis. | pmid:10839763 |
Heikkinen T et al. | The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin. | 2000 | BJOG | pmid:10847234 |
Raja Babu KK et al. | Confluent and reticulate papillomatosis: successful treatment with azithromycin. | 2000 | Br. J. Dermatol. | pmid:10848767 |
Ernst EJ et al. | Comparison of the serum and intracellular pharmacokinetics of azithromycin in healthy and diabetic volunteers. | 2000 | Pharmacotherapy | pmid:10853621 |
Criqui GI et al. | Effects of azithromycin on ozone-induced airway neutrophilia and cytokine release. | 2000 | Eur. Respir. J. | pmid:10853849 |
Plouffe J et al. | Clinical efficacy of intravenous followed by oral azithromycin monotherapy in hospitalized patients with community-acquired pneumonia. The Azithromycin Intravenous Clinical Trials Group. | 2000 | Antimicrob. Agents Chemother. | pmid:10858333 |
Chinh NT et al. | A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. | 2000 | Antimicrob. Agents Chemother. | pmid:10858343 |
Miltner EC and Bermudez LE | Mycobacterium avium grown in Acanthamoeba castellanii is protected from the effects of antimicrobials. | 2000 | Antimicrob. Agents Chemother. | pmid:10858369 |
SendaÄŸ F et al. | Single dose oral azithromycin versus seven day doxycycline in the treatment of non-gonococcal mucopurulent endocervicitis. | 2000 | Aust N Z J Obstet Gynaecol | pmid:10870778 |
Scharfstein JA et al. | The cost-effectiveness of prophylaxis for Mycobacterium avium complex in AIDS. | 1999 | Int J Technol Assess Health Care | pmid:10874380 |
Gruber F et al. | Treatment of early syphilis with azithromycin. | 2000 | J Chemother | pmid:10877520 |
Barsic B et al. | Comparison of azithromycin and doxycycline in the treatment of erythema migrans. | 2000 May-Jun | Infection | pmid:10879639 |
Koch CC et al. | Apoptosis, oxidative metabolism and interleukin-8 production in human neutrophils exposed to azithromycin: effects of Streptococcus pneumoniae. | 2000 | J. Antimicrob. Chemother. | pmid:10882684 |
Herrera D et al. | The periodontal abscess (II). Short-term clinical and microbiological efficacy of 2 systemic antibiotic regimes. | 2000 | J. Clin. Periodontol. | pmid:10883868 |
McBroom JW | Medical management of interstitial pregnancy with a retained IUD. A case report. | 2000 | J Reprod Med | pmid:10900583 |
Drugs for sexually transmitted infections. | 1999 | Med Lett Drugs Ther | pmid:10906932 | |
Gomperts BN and White LK | Gonococcal hand abscess. | 2000 | Pediatr. Infect. Dis. J. | pmid:10917235 |
Hammerschlag MR | Treatment of Chlamydia pneumoniae. | 2000 | Int. J. Antimicrob. Agents | pmid:10926449 |
Rekart M et al. | Mass treatment/prophylaxis during an outbreak of infectious syphilis in Vancouver, British Columbia. | 2000 | Can. Commun. Dis. Rep. | pmid:10932390 |
Ng DK et al. | A randomized controlled trial of azithromycin and amoxycillin/clavulanate in the management of subacute childhood rhinosinusitis. | 2000 | J Paediatr Child Health | pmid:10940175 |
Vranes J | Effect of subminimal inhibitory concentrations of azithromycin on adherence of Pseudomonas aeruginosa to polystyrene. | 2000 | J Chemother | pmid:10949976 |
Dean D et al. | Evidence for long-term cervical persistence of Chlamydia trachomatis by omp1 genotyping. | 2000 | J. Infect. Dis. | pmid:10950788 |
Mandell GL and Coleman EJ | Activities of antimicrobial agents against intracellular pneumococci. | 2000 | Antimicrob. Agents Chemother. | pmid:10952618 |
Thompson C | Azithromycin v oxytetracycline for the treatment of non-specific urethritis. | 2000 | Sex Transm Infect | pmid:10961211 |
Scaglione F et al. | In vitro comparative dynamics of modified-release clarithromycin and of azithromycin. | 2000 Sep-Oct | Chemotherapy | pmid:10965100 |
Guzey M et al. | Three-day course of oral azithromycin vs topical oxytetracycline/polymyxin in treatment of active endemic trachoma. | 2000 Jul-Aug | Jpn. J. Ophthalmol. | pmid:10974295 |
Jonas D et al. | The effect of azithromycin on intracellular Legionella pneumophila in the Mono Mac 6 cell line at serum concentrations attainable in vivo. | 2000 | J. Antimicrob. Chemother. | pmid:10980164 |
Schouenborg P et al. | Azithromycin versus pivampicillin in the treatment of acute exacerbations of chronic bronchitis: a single-blind, double-dummy, multicentre study. | 2000 May-Jun | J. Int. Med. Res. | pmid:10983860 |
Fogarty C et al. | Bacteremic pneumonia due to multidrug-resistant pneumococci in 3 patients treated unsuccessfully with azithromycin and successfully with levofloxacin. | 2000 | Clin. Infect. Dis. | pmid:10987733 |
Ohtani H et al. | Comparative pharmacodynamic analysis of Q-T interval prolongation induced by the macrolides clarithromycin, roxithromycin, and azithromycin in rats. | 2000 | Antimicrob. Agents Chemother. | pmid:10991836 |
Beckey NP et al. | Retrospective evaluation of a potential interaction between azithromycine and warfarin in patients stabilized on warfarin. | 2000 | Pharmacotherapy | pmid:10999497 |
Flores S et al. | [Triple therapy of short-term with azithromycin, amoxycillin and omeprazole for the eradication of Helicobacter pylori]. | 2000 | Rev Med Chil | pmid:11008354 |
Fluoroquinolone-resistance in Neisseria gonorrhoeae, Hawaii, 1999, and decreased susceptibility to azithromycin in N. gonorrhoeae, Missouri, 1999. | 2000 | MMWR Morb. Mortal. Wkly. Rep. | pmid:11012233 | |
Erhardt W et al. | Establishing criteria for assessment of efficacy of antimicrobial agents in acute otitis media. | 2000 | Antimicrob. Agents Chemother. | pmid:11012390 |
Westphal JF | Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin. | 2000 | Br J Clin Pharmacol | pmid:11012550 |
Currier JS et al. | Discontinuation of Mycobacterium avium complex prophylaxis in patients with antiretroviral therapy-induced increases in CD4+ cell count. A randomized, double-blind, placebo-controlled trial. AIDS Clinical Trials Group 362 Study Team. | 2000 | Ann. Intern. Med. | pmid:11015162 |
Schneider CA et al. | In vivo uptake of azithromycin in human coronary plaques. | 2000 | Am. J. Cardiol. | pmid:11018204 |
Kuper JI and D'Aprile M | Drug-Drug interactions of clinical significance in the treatment of patients with Mycobacterium avium complex disease. | 2000 | Clin Pharmacokinet | pmid:11020135 |
Grayston JT | Secondary prevention antibiotic treatment trials for coronary artery disease. | 2000 | Circulation | pmid:11023925 |
Muhlestein JB et al. | Randomized secondary prevention trial of azithromycin in patients with coronary artery disease: primary clinical results of the ACADEMIC study. | 2000 | Circulation | pmid:11023928 |
Granowitz EV et al. | Potentially fatal interaction between azithromycin and disopyramide. | 2000 | Pacing Clin Electrophysiol | pmid:11025903 |
Semaan HB et al. | The effect of chronic azithromycin therapy on soluble endothelium-derived adhesion molecules in patients with coronary artery disease. | 2000 | J. Cardiovasc. Pharmacol. | pmid:11026657 |
Miller JM and Martin DH | Treatment of Chlamydia trachomatis infections in pregnant women. | 2000 | Drugs | pmid:11030469 |
Ghaffar F et al. | Effects of amoxicillin/clavulanate or azithromycin on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae in children with acute otitis media. | 2000 | Clin. Infect. Dis. | pmid:11049764 |
Kelley MA et al. | Breakthrough pneumococcal bacteremia in patients being treated with azithromycin and clarithromycin. | 2000 | Clin. Infect. Dis. | pmid:11049784 |
Adachi JA et al. | Empirical antimicrobial therapy for traveler's diarrhea. | 2000 | Clin. Infect. Dis. | pmid:11049792 |