Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Salimi A et al. | Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. | 2016 | Xenobiotica | pmid:26068526 |
| Martande SS et al. | Clinical and microbiological effects of systemic azithromycin in adjunct to nonsurgical periodontal therapy in treatment of Aggregatibacter actinomycetemcomitans associated periodontitis: a randomized placebo-controlled clinical trial. | 2016 | J Investig Clin Dent | pmid:25044531 |
| van den Berg GF et al. | Chlamydia screening and prophylactic treatment in termination of pregnancy clinics in the Netherlands and Great Britain: a qualitative study. | 2016 | Eur J Contracept Reprod Health Care | pmid:27701927 |
| EmiralioÄŸlu N et al. | Long term azithromycin therapy in patients with cystic fibrosis. | 2016 | Turk. J. Pediatr. | pmid:27922234 |
| Mougari F et al. | Infections caused by Mycobacterium abscessus: epidemiology, diagnostic tools and treatment. | 2016 | Expert Rev Anti Infect Ther | pmid:27690688 |
| Johnston SL et al. | Azithromycin for Acute Exacerbations of Asthma : The AZALEA Randomized Clinical Trial. | 2016 | JAMA Intern Med | pmid:27653939 |
| Zhao X et al. | Sensitive and Simplified Detection of Antibiotic Influence on the Dynamic and Versatile Changes of Fecal Short-Chain Fatty Acids. | 2016 | PLoS ONE | pmid:27907030 |
| Mosquera RA et al. | Anti-inflammatory effect of prophylactic macrolides on children with chronic lung disease: a protocol for a double-blinded randomised controlled trial. | 2016 | BMJ Open | pmid:27638496 |
| Kissinger PJ et al. | Azithromycin Treatment Failure for Chlamydia trachomatis Among Heterosexual Men With Nongonococcal Urethritis. | 2016 | Sex Transm Dis | pmid:27631353 |
| Nielsen HL et al. | Azithromycin vs. Placebo for the Clinical Outcome in Campylobacter concisus Diarrhoea in Adults: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial. | 2016 | PLoS ONE | pmid:27893820 |
| Tepper M et al. | Mass Treatment with Single-Dose Azithromycin for Yaws. | 2016 | N. Engl. J. Med. | pmid:27626527 |
| Phiri K et al. | Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with Plasmodium Falciparum Parasitemia: An Open-Label, Non-Comparative Study in Sub-Saharan Africa. | 2016 | PLoS ONE | pmid:27861509 |
| Eckhoff G et al. | Mass Treatment with Single-Dose Azithromycin for Yaws. | 2016 | N. Engl. J. Med. | pmid:27626526 |
| Peart JM et al. | Sporotrichoid fluctuant nodules. | 2016 | Cutis | pmid:27622258 |
| Malhotra S et al. | Prevalence of Trachoma in Car-Nicobar Island, India after Three Annual Rounds of Mass Drug Administration with Azithromycin. | 2016 | PLoS ONE | pmid:27391274 |
| Marks M | Yaws: towards the WHO eradication target. | 2016 | Trans. R. Soc. Trop. Med. Hyg. | pmid:27268712 |
| Liu B et al. | Relationship between Community Drug Administration Strategy and Changes in Trachoma Prevalence, 2007 to 2013. | 2016 | PLoS Negl Trop Dis | pmid:27385309 |
| Long SS | Optimizing antimicrobial therapy in children. | 2016 | J. Infect. | pmid:27263076 |
| Katanami Y et al. | Six Cases of Paratyphoid Fever Due to Salmonella Paratyphi A in Travelers Returning from Myanmar Between July 2014 and August 2015. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27352874 |
| Mertens TC et al. | Azithromycin differentially affects the IL-13-induced expression profile in human bronchial epithelial cells. | 2016 | Pulm Pharmacol Ther | pmid:27246785 |
| Wang X et al. | Increased therapeutic efficacy of combination of azithromycin and ceftazidime on Pseudomonas aeruginosa biofilm in an animal model of ureteral stent infection. | 2016 | BMC Microbiol. | pmid:27341798 |
| Das S et al. | Revisit of fluoroquinolone and azithromycin susceptibility breakpoints for Salmonella enterica serovar Typhi. | 2016 | J. Med. Microbiol. | pmid:27221661 |
| Fifer H et al. | Failure of Dual Antimicrobial Therapy in Treatment of Gonorrhea. | 2016 | N. Engl. J. Med. | pmid:27332921 |
| Bacharier LB et al. | Early Azithromycin Treatment to Prevent Severe Lower Respiratory Tract Illnesses in Children--Reply. | 2016 | JAMA | pmid:27187309 |
| Gesink D et al. | Mycoplasma genitalium in Toronto, Ont: Estimates of prevalence and macrolide resistance. | 2016 | Can Fam Physician | pmid:27331225 |
| Fleming-Dutra KE et al. | Early Azithromycin Treatment to Prevent Severe Lower Respiratory Tract Illnesses in Children. | 2016 | JAMA | pmid:27187308 |
| Kimani J et al. | Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial. | 2016 | PLoS ONE | pmid:27326859 |
| Morgan R et al. | Unusual cause of lymphangitis in a 2-year-old boy. | 2016 | BMJ Case Rep | pmid:27181743 |
| Weckmann M et al. | Treatment with rhDNase in patients with cystic fibrosis alters in-vitro CHIT-1 activity of isolated leucocytes. | 2016 | Clin. Exp. Immunol. | pmid:27324468 |
| Kong FY et al. | Higher organism load associated with failure of azithromycin to treat rectal chlamydia. | 2016 | Epidemiol. Infect. | pmid:27180823 |
| Farrell DJ et al. | Results from the Solithromycin International Surveillance Program (2014). | 2016 | Antimicrob. Agents Chemother. | pmid:27044551 |
| Mathew JL et al. | Oral Azithromycin for Acute Episodic Airway Symptoms in Young Children: Evidence-based Medicine Viewpoint. | 2016 | Indian Pediatr | pmid:27029689 |
| Pavlović D and Mutak S | Synthesis and antibacterial evaluation of novel 4″-glycyl linked quinolyl-azithromycins with potent activity against macrolide-resistant pathogens. | 2016 | Bioorg. Med. Chem. | pmid:26860929 |
| Roca A et al. | Oral azithromycin given during labour decreases bacterial carriage in the mothers and their offspring: a double-blind randomized trial. | 2016 | Clin. Microbiol. Infect. | pmid:27026482 |
| Oey M and Malhotra P | Azithromycin and ceftriaxone combination treatment for relapsed Salmonella Paratyphi A bacteraemia. | 2016 | J Travel Med | pmid:26858276 |
| DeCoster B et al. | Expedited Partner Therapy: Clinical Considerations and Public Health Explorations. | 2016 | AMA J Ethics | pmid:27002992 |
| Zhou T et al. | Determination of azithromycin residue in pork using a molecularly imprinted monolithic microcolumn coupled to liquid chromatography with tandem mass spectrometry. | 2016 | J Sep Sci | pmid:26854282 |
| Das MC et al. | Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. | 2016 | Sci Rep | pmid:27000525 |
| Saleh A et al. | Comparison of adjunctive azithromycin and amoxicillin/metronidazole for patients with chronic periodontitis: preliminary randomized control trial. | 2016 | Aust Dent J | pmid:26836781 |
| Maeda M et al. | Study on rectal administration of azithromycin by suppository for pediatric use. | 2016 | Int J Clin Pharmacol Ther | pmid:26833461 |
| Jost C et al. | Susceptibility of enterohaemorrhagic Escherichia coli to azithromycin in France and analysis of resistance mechanisms. | 2016 | J. Antimicrob. Chemother. | pmid:26832755 |
| Topp E et al. | Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. | 2016 | Sci. Total Environ. | pmid:27096634 |
| Li X et al. | Macrolides use and the risk of sudden cardiac death. | 2016 | Expert Rev Anti Infect Ther | pmid:27086751 |
| Liu H et al. | [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:26875461 |
| Arnold FW et al. | Macrolide Use and Neutrophil Function/Cytokine Levels in Hospitalized Patients with Community-Acquired Pneumonia: A Pilot Study. | 2016 | Lung | pmid:26553025 |
| Olszewska-Sosińska O et al. | Persistence of non-typeable Haemophilus Influenzae in the pharynx of children with adenotonsillar hypertrophy after treatment with azithromycin. | 2016 | Pathog Dis | pmid:26546328 |
| Wakiguchi H et al. | Multiple Renal and Splenic Lesions in Cat Scratch Disease. | 2016 | Jpn. J. Infect. Dis. | pmid:26567841 |
| So W et al. | Poor outcomes of empiric ceftriaxone ± azithromycin for community-acquired pneumonia caused by methicillin-susceptible Staphylococcus aureus. | 2016 | Intern Emerg Med | pmid:26531307 |
| Amantea D et al. | Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype. | 2016 | Exp. Neurol. | pmid:26518285 |
| VÃchová B et al. | First molecular identification of Babesia gibsoni in dogs from Slovakia, central Europe. | 2016 | Ticks Tick Borne Dis | pmid:26304014 |
| Bhargava A et al. | Scrub typhus in Uttarakhand & adjoining Uttar Pradesh: Seasonality, clinical presentations & predictors of mortality. | 2016 | Indian J. Med. Res. | pmid:28474627 |
| Fegan D et al. | Tropical leg ulcers in children: more than yaws. | 2016 | Trop Doct | pmid:26289420 |
| Kasten G et al. | Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery. | 2016 | Drug Dev Ind Pharm | pmid:26289002 |
| Lee RA et al. | Evaluation of baseline corrected QT interval and azithromycin prescriptions in an academic medical center. | 2016 | J Hosp Med | pmid:26287278 |
| Narayanasamy DK et al. | Clinico - Laboratory Profile of Scrub Typhus - An Emerging Rickettsiosis in India. | 2016 | Indian J Pediatr | pmid:27352842 |
| Keenan JD et al. | Nasopharyngeal Pneumococcal Serotypes Before and After Mass Azithromycin Distributions for Trachoma. | 2016 | J Pediatric Infect Dis Soc | pmid:27199475 |
| Tous Romero F et al. | Acute Infection by Staphylococcus simulans in the Hand of a Man. | 2016 | JAMA Dermatol | pmid:27144675 |
| Horner P et al. | 2015 UK National Guideline on the management of non-gonococcal urethritis. | 2016 | Int J STD AIDS | pmid:26002319 |
| Ni C et al. | High prevalence of Neisseria gonorrhoeae with high-level resistance to azithromycin in Hangzhou, China. | 2016 | J. Antimicrob. Chemother. | pmid:27090631 |
| Garnier C et al. | Intra-nodal injection of gentamicin for the treatment of suppurated cat scratch disease's lymphadenitis. | 2016 | Infection | pmid:26001741 |
| Hazra A | Author Reply. | 2016 Jan-Feb | Indian J Pharmacol | pmid:26997735 |
| Das S and Mohanty M | Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. | 2016 Jan-Feb | Indian J Pharmacol | pmid:26997734 |
| Das A et al. | Azithromycin induced bullous fixed drug eruption. | 2016 Jan-Feb | Indian J Pharmacol | pmid:26997729 |
| Chatterjee S et al. | Azithromycin susceptibility among clinical isolates of Salmonella: Interfacing guidelines with routine practices. | 2016 Jul-Sep | Indian J Med Microbiol | pmid:27514976 |
| Latif SA et al. | Azithromycin buccal patch in treatment of chronic periodontitis. | 2016 Mar-Apr | Indian J Pharmacol | pmid:27127325 |
| Oliveira IS et al. | Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. | 2016 Mar-Apr | Braz J Otorhinolaryngol | pmid:26601998 |
| Akoglu G et al. | Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. | 2016 May-Jun | Indian J Pharmacol | pmid:27298507 |
| Diniz LM et al. | Bacillary angiomatosis with bone invasion. | 2016 Nov-Dec | An Bras Dermatol | pmid:28099606 |
| Trembizki E et al. | High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia. | 2017 | J. Med. Microbiol. | pmid:28893363 |
| Horner PJ and Martin DH | Mycoplasma genitalium Infection in Men. | 2017 | J. Infect. Dis. | pmid:28838074 |
| Pavlinac PB et al. | Azithromycin to prevent post-discharge morbidity and mortality in Kenyan children: a protocol for a randomised, double-blind, placebo-controlled trial (the Toto Bora trial). | 2017 | BMJ Open | pmid:29289941 |
| Last AR et al. | The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma-endemic island communities in West Africa. | 2017 | Parasit Vectors | pmid:29282126 |
| Stieler Stewart AL et al. | Effects of clarithromycin, azithromycin and rifampicin on terbutaline-induced sweating in foals. | 2017 | Equine Vet. J. | pmid:28238211 |
| Allan RN et al. | Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms. | 2017 | Nitric Oxide | pmid:28235635 |
| Wiesenfeld HC | Screening for Chlamydia trachomatis Infections in Women. | 2017 | N. Engl. J. Med. | pmid:28225683 |
| Shmarina G et al. | Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression. | 2017 | Int. Arch. Allergy Immunol. | pmid:28219060 |
| Cluver C et al. | Interventions for treating genital Chlamydia trachomatis infection in pregnancy. | 2017 | Cochrane Database Syst Rev | pmid:28937705 |
| Sonavane AD and Rathi PM | Fitz-Hugh-Curtis syndrome. | 2017 | Indian J. Med. Res. | pmid:28574030 |
| Ra SW et al. | Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. | 2017 | Respir. Res. | pmid:28558695 |
| Campanón-Toro MV et al. | Acute generalized exanthematous pustulosis (AGEP) induced by azithromycin. | 2017 | Contact Derm. | pmid:28497632 |
| Rutenberg D et al. | Efficacy of Tulathromycin for the Treatment of Foals with Mild to Moderate Bronchopneumonia. | 2017 | J. Vet. Intern. Med. | pmid:28421633 |
| Trifirò G et al. | Use of azithromycin and risk of ventricular arrhythmia. | 2017 | CMAJ | pmid:28420680 |
| Amza A et al. | A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children. | 2017 | Clin. Infect. Dis. | pmid:27956455 |
| Papp JR et al. | Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA. | 2017 | Emerging Infect. Dis. | pmid:28418303 |
| Liu Y et al. | Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. | 2017 | Life Sci. | pmid:27916734 |
| Valdés SO et al. | Cardiac Arrest in Pediatric Patients Receiving Azithromycin. | 2017 | J. Pediatr. | pmid:27912925 |
| Foerster S et al. | A new rapid resazurin-based microdilution assay for antimicrobial susceptibility testing of Neisseria gonorrhoeae. | 2017 | J. Antimicrob. Chemother. | pmid:28431096 |
| Murphy TK et al. | A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder. | 2017 | J Child Adolesc Psychopharmacol | pmid:28358599 |
| Eyre DW et al. | WGS to predict antibiotic MICs for Neisseria gonorrhoeae. | 2017 | J. Antimicrob. Chemother. | pmid:28333355 |
| Thompson DF and Ramos CL | Antibiotic-Induced Rash in Patients With Infectious Mononucleosis. | 2017 | Ann Pharmacother | pmid:27620494 |
| Rajesh AM and Popat KM | Taste masking of azithromycin by resin complex and sustained release through interpenetrating polymer network with functionalized biopolymers. | 2017 | Drug Dev Ind Pharm | pmid:27600608 |
| Romero L et al. | Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. | 2017 | Cochrane Database Syst Rev | pmid:29226307 |
| Dror T et al. | Microbiota manipulation for weight change. | 2017 | Microb. Pathog. | pmid:26792677 |
| Lusk MJ et al. | Cervicitis: a prospective observational study of empiric azithromycin treatment in women with cervicitis and non-specific cervicitis. | 2017 | Int J STD AIDS | pmid:26792283 |
| Burr SE et al. | Does azithromycin given to women in labour decrease ocular bacterial infection in neonates? A double-blind, randomized trial. | 2017 | BMC Infect. Dis. | pmid:29282015 |
| Marks M and Mabey D | Single-dose azithromycin to treat latent yaws. | 2017 | Lancet Glob Health | pmid:29107622 |
| Thompson CN et al. | Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal. | 2017 | Clin. Infect. Dis. | pmid:28329181 |
| Emerging risk of untreatable gonorrhea and what to do about it. | 2017 | Can Fam Physician | pmid:28292798 | |
| Halhal B et al. | Pertussis Outbreak Among Soldiers During Basic Training: The Need for Updated Protocols. | 2017 | Mil Med | pmid:28291499 |
| Çelik Payçu DG and Büyükbaba Boral Ö | [Effects of azithromycin and Chlorella vulgaris treatment on certain cytokine values and NK cell activity in an acute murine toxoplasmosis model]. | 2017 | Mikrobiyol Bul | pmid:28283010 |