Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Walsh MS et al. | Prevalence of Chlamydia trachomatis infection in Samoan women aged 18 to 29 and assessment of possible risk factors: a community-based study. | 2015 | Trans. R. Soc. Trop. Med. Hyg. | pmid:25732755 |
| Hamasuna R et al. | The second nationwide surveillance of the antimicrobial susceptibility of Neisseria gonorrhoeae from male urethritis in Japan, 2012-2013. | 2015 | J. Infect. Chemother. | pmid:25727286 |
| Gershengorn HB et al. | The association of antibiotic treatment regimen and hospital mortality in patients hospitalized with Legionella pneumonia. | 2015 | Clin. Infect. Dis. | pmid:25722195 |
| Min KW et al. | Education and imaging. Gastrointestinal: a case of histologically confirmed scrub typhus gastritis. | 2015 | J. Gastroenterol. Hepatol. | pmid:25707787 |
| Wessels MR et al. | Case records of the Massachusetts General Hospital. Case 6-2015. A 16-year-old boy with coughing spells. | 2015 | N. Engl. J. Med. | pmid:25693017 |
| Principi N et al. | Azithromycin use in patients with cystic fibrosis. | 2015 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:25686729 |
| Zheng H et al. | Association of the in vitro susceptibility of clinical isolates of chlamydia trachomatis with serovar and duration of antibiotic exposure. | 2015 | Sex Transm Dis | pmid:25668641 |
| Nemes-Nikodém É et al. | [Antimicrobal resistance of Neisseria gonorrhoeae strains in Hungary]. | 2015 | Orv Hetil | pmid:25639637 |
| Kong FY et al. | The efficacy of azithromycin and doxycycline for the treatment of rectal chlamydia infection: a systematic review and meta-analysis. | 2015 | J. Antimicrob. Chemother. | pmid:25637520 |
| Sutton AL et al. | Perinatal pharmacokinetics of azithromycin for cesarean prophylaxis. | 2015 | Am. J. Obstet. Gynecol. | pmid:25595580 |
| Saini H et al. | Azithromycin and ciprofloxacin: a possible synergistic combination against Pseudomonas aeruginosa biofilm-associated urinary tract infections. | 2015 | Int. J. Antimicrob. Agents | pmid:25604277 |
| Krenn K et al. | Effects of azithromycin and tanomastat on experimental bronchiolitis obliterans. | 2015 | J. Thorac. Cardiovasc. Surg. | pmid:25595376 |
| Unger HW et al. | Sulphadoxine-pyrimethamine plus azithromycin for the prevention of low birthweight in Papua New Guinea: a randomised controlled trial. | 2015 | BMC Med | pmid:25591391 |
| Kwon HJ et al. | Megalocytic interstitial nephritis following acute pyelonephritis with Escherichia coli bacteremia: a case report. | 2015 | J. Korean Med. Sci. | pmid:25552891 |
| Hauser C et al. | In vitro activity of fosfomycin alone and in combination with ceftriaxone or azithromycin against clinical Neisseria gonorrhoeae isolates. | 2015 | Antimicrob. Agents Chemother. | pmid:25547354 |
| Marks M et al. | Yaws. | 2015 | Br. Med. Bull. | pmid:25525120 |
| Kadova Z et al. | IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats. | 2015 | Am. J. Physiol. Renal Physiol. | pmid:25503728 |
| Lu ZK et al. | Cardiac risks associated with antibiotics: azithromycin and levofloxacin. | 2015 | Expert Opin Drug Saf | pmid:25494485 |
| Kasai A et al. | Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011. | 2015 | J. Med. Microbiol. | pmid:25934551 |
| Bissessor M et al. | Persistence of Neisseria gonorrhoeae DNA following treatment for pharyngeal and rectal gonorrhea is influenced by antibiotic susceptibility and reinfection. | 2015 | Clin. Infect. Dis. | pmid:25371490 |
| Ohara H et al. | Azithromycin Can Prolong QT Interval and Suppress Ventricular Contraction, but Will Not Induce Torsade de Pointes. | 2015 | Cardiovasc. Toxicol. | pmid:25367413 |
| Stamm LV | Syphilis: antibiotic treatment and resistance. | 2015 | Epidemiol. Infect. | pmid:25358292 |
| Jayarathna YR et al. | Analyzing the necessity of prophylactic antibiotic usage in laparoscopy for uncomplicated gynecologic conditions in Sri Lanka. | 2015 | J. Obstet. Gynaecol. Res. | pmid:25331108 |
| Merchan LM et al. | Pharmacokinetics, microbial response, and pulmonary outcomes of multidose intravenous azithromycin in preterm infants at risk for Ureaplasma respiratory colonization. | 2015 | Antimicrob. Agents Chemother. | pmid:25385115 |
| Schögler A et al. | Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells. | 2015 | Eur. Respir. J. | pmid:25359346 |
| Dubois J et al. | In vitro and intracellular activities of peptide deformylase inhibitor GSK1322322 against Legionella pneumophila isolates. | 2015 | Antimicrob. Agents Chemother. | pmid:25348534 |
| Hodge S et al. | Increased CD8 T-cell granzyme B in COPD is suppressed by treatment with low-dose azithromycin. | 2015 | Respirology | pmid:25308201 |
| Li Y et al. | Where macrolide resistance is prevalent. | 2015 | APMIS | pmid:25703275 |
| Keenan JD et al. | Evidence for clonal expansion after antibiotic selection pressure: pneumococcal multilocus sequence types before and after mass azithromycin treatments. | 2015 | J. Infect. Dis. | pmid:25293366 |
| Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
| Sandrock CE and Norris A | Infection in severe asthma exacerbations and critical asthma syndrome. | 2015 | Clin Rev Allergy Immunol | pmid:24984968 |
| Aucamp M et al. | Amorphous azithromycin with improved aqueous solubility and intestinal membrane permeability. | 2015 | Drug Dev Ind Pharm | pmid:24980913 |
| Young PM et al. | Multi-breath dry powder inhaler for delivery of cohesive powders in the treatment of bronchiectasis. | 2015 | Drug Dev Ind Pharm | pmid:24811055 |
| Cabeza J et al. | Feasibility of Chlamydia trachomatis screening and treatment in pregnant women in Lima, Peru: a prospective study in two large urban hospitals. | 2015 | Sex Transm Infect | pmid:25107711 |
| Willekens J et al. | How long should we maintain long-term azithromycin treatment in cystic fibrosis patients? | 2015 | Pediatr. Pulmonol. | pmid:24464958 |
| Méndez Abad P et al. | Idiopathic plastic bronchitis as an uncommon cause of massive pulmonary atelectasis. | 2015 | Arch. Bronconeumol. | pmid:24495947 |
| MaraÄić S et al. | 1,2,3-Triazole pharmacophore-based benzofused nitrogen/sulfur heterocycles with potential anti-Moraxella catarrhalis activity. | 2015 | Bioorg. Med. Chem. | pmid:26578325 |
| Zhang B et al. | Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury. | 2015 | J Neuroinflammation | pmid:26597676 |
| Cohen RT and Pelton SI | Individual Benefit vs Societal Effect of Antibiotic Prescribing for Preschool Children With Recurrent Wheeze. | 2015 | JAMA | pmid:26575058 |
| Roca A et al. | Prevention of bacterial infections in the newborn by pre-delivery administration of azithromycin: Study protocol of a randomized efficacy trial. | 2015 | BMC Pregnancy Childbirth | pmid:26585192 |
| Bacharier LB et al. | Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. | 2015 | JAMA | pmid:26575060 |
| Hemmige V et al. | Recurrent skin and soft tissue infections in HIV-infected patients during a 5-year period: incidence and risk factors in a retrospective cohort study. | 2015 | BMC Infect. Dis. | pmid:26503616 |
| Su XH et al. | Multidrug-Resistant Neisseria gonorrhoeae Isolates from Nanjing, China, Are Sensitive to Killing by a Novel DNA Gyrase Inhibitor, ETX0914 (AZD0914). | 2015 | Antimicrob. Agents Chemother. | pmid:26482313 |
| Pogany L et al. | Management of gonococcal infection among adults and youth: New key recommendations. | 2015 | Can Fam Physician | pmid:26472793 |
| Jesus FP et al. | In Vitro and In Vivo Antimicrobial Activities of Minocycline in Combination with Azithromycin, Clarithromycin, or Tigecycline against Pythium insidiosum. | 2015 | Antimicrob. Agents Chemother. | pmid:26459895 |
| Azzam O et al. | Rhodococcus equi peritonitis in continuous ambulatory peritoneal dialysis: a first in Australia. | 2015 | BMJ Case Rep | pmid:26438670 |
| ACOG Committee Opinion No. 645: Dual Therapy for Gonococcal Infections. | 2015 | Obstet Gynecol | pmid:26488526 | |
| Shibahara D et al. | Falciparum Malaria Incidentally Pretreated with Azithromycin. | 2015 | Intern. Med. | pmid:26424314 |
| ACOG Committee Opinion No. 645 Summary: Dual Therapy for Gonococcal Infections. | 2015 | Obstet Gynecol | pmid:26488518 | |
| Wei HX et al. | A Systematic Review and Meta-Analysis of the Efficacy of Anti-Toxoplasma gondii Medicines in Humans. | 2015 | PLoS ONE | pmid:26394212 |
| Babics A and Roussellier P | Gardnerella vaginalis: An overlooked pathogen in male patients? | 2015 | Med Mal Infect | pmid:26472061 |
| See CW et al. | The Effect of Mass Azithromycin Distribution on Childhood Mortality: Beliefs and Estimates of Efficacy. | 2015 | Am. J. Trop. Med. Hyg. | pmid:26392160 |
| Winters N et al. | Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment. | 2015 | Eur. Respir. J. | pmid:26381514 |
| Kong FY and Hocking JS | Treatment challenges for urogenital and anorectal Chlamydia trachomatis. | 2015 | BMC Infect. Dis. | pmid:26220080 |
| Falk L et al. | Time to eradication of Mycoplasma genitalium after antibiotic treatment in men and women. | 2015 | J. Antimicrob. Chemother. | pmid:26283670 |
| Å majs D et al. | Macrolide Resistance in the Syphilis Spirochete, Treponema pallidum ssp. pallidum: Can We Also Expect Macrolide-Resistant Yaws Strains? | 2015 | Am. J. Trop. Med. Hyg. | pmid:26217043 |
| Beigelman A et al. | Does azithromycin modify viral load during severe respiratory syncytial virus bronchiolitis? | 2015 | J. Allergy Clin. Immunol. | pmid:26215052 |
| Fonseca DC et al. | Clinical and Microbiologic Evaluation of Scaling and Root Planing per Quadrant and One-Stage Full-Mouth Disinfection Associated With Azithromycin or Chlorhexidine: A Clinical Randomized Controlled Trial. | 2015 | J. Periodontol. | pmid:26252751 |
| Pereira A et al. | Acute onset of widespread pustular eruption. | 2015 | Aust Fam Physician | pmid:26209988 |
| O'Beirne SL et al. | Severe Cavitary, Fistulating Mycobacterium avium-intracellulare Complex Disease in an Immunocompetent Host. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:26244303 |
| Zhang L et al. | Effects of azithromycin on gene expression profiles of proinflammatory and anti-inflammatory mediators in the eyelid margin and conjunctiva of patients with meibomian gland disease. | 2015 | JAMA Ophthalmol | pmid:26204109 |
| Wilson DW et al. | Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum. | 2015 | BMC Biol. | pmid:26187647 |
| Zhanel GG et al. | Clinical cure rates in subjects treated with azithromycin for community-acquired respiratory tract infections caused by azithromycin-susceptible or azithromycin-resistant Streptococcus pneumoniae: analysis of Phase 3 clinical trial data-authors' response. | 2015 | J. Antimicrob. Chemother. | pmid:26242414 |
| Brill SE et al. | Effects of different antibiotic classes on airway bacteria in stable COPD using culture and molecular techniques: a randomised controlled trial. | 2015 | Thorax | pmid:26179246 |
| Horner PJ | Editorial Commentary: Mycoplasma genitalium and Declining Treatment Efficacy of Azithromycin 1 g: What Can We Do? | 2015 | Clin. Infect. Dis. | pmid:26240204 |
| Medina AM et al. | Comparative analysis of antimicrobial resistance in enterotoxigenic Escherichia coli isolates from two paediatric cohort studies in Lima, Peru. | 2015 | Trans. R. Soc. Trop. Med. Hyg. | pmid:26175267 |
| Lau A et al. | The Efficacy of Azithromycin for the Treatment of Genital Mycoplasma genitalium: A Systematic Review and Meta-analysis. | 2015 | Clin. Infect. Dis. | pmid:26240201 |
| West SK et al. | Risk of Infection with Chlamydia trachomatis from Migrants to Communities Undergoing Mass Drug Administration for Trachoma Control. | 2015 | Ophthalmic Epidemiol | pmid:26158574 |
| Goldstein LH et al. | Azithromycin is not associated with QT prolongation in hospitalized patients with community-acquired pneumonia. | 2015 | Pharmacoepidemiol Drug Saf | pmid:26238864 |
| Gebresillasie S et al. | Inter-Rater Agreement between Trachoma Graders: Comparison of Grades Given in Field Conditions versus Grades from Photographic Review. | 2015 | Ophthalmic Epidemiol | pmid:26158573 |
| Gualdoni GA et al. | Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation. | 2015 | Sci Rep | pmid:26152605 |
| Unemo M et al. | High in vitro susceptibility to the novel spiropyrimidinetrione ETX0914 (AZD0914) among 873 contemporary clinical Neisseria gonorrhoeae isolates from 21 European countries from 2012 to 2014. | 2015 | Antimicrob. Agents Chemother. | pmid:26077246 |
| Cowling CS et al. | National trachoma surveillance annual report, 2012. | 2015 | Commun Dis Intell Q Rep | pmid:26063088 |
| Lahra MM | Australian Gonococcal Surveillance Programme annual report, 2013. | 2015 | Commun Dis Intell Q Rep | pmid:26063087 |
| Bérard A et al. | Use of macrolides during pregnancy and the risk of birth defects: a population-based study. | 2015 | Pharmacoepidemiol Drug Saf | pmid:26513406 |
| Buset SL et al. | Non-surgical periodontal therapy supplemented with systemically administered azithromycin: a systematic review of RCTs. | 2015 | Clin Oral Investig | pmid:26063646 |
| Yin SM et al. | Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. | 2015 | J. Clin. Immunol. | pmid:26048260 |
| Abely M et al. | [National consensus regarding azithromycin use in cystic fibrosis]. | 2015 | Rev Mal Respir | pmid:26003196 |
| Escalante MG et al. | Comparison of Azithromycin and Amoxicillin Before Dental Implant Placement: An Exploratory Study of Bioavailability and Resolution of Postoperative Inflammation. | 2015 | J. Periodontol. | pmid:26252749 |
| Carter N and Horner P | Treatment regimens in non-gonococcal urethritis. | 2015 | Sex Transm Infect | pmid:25990780 |
| Barve A et al. | The effects of CYP3A4 induction and inhibition on the pharmacokinetics of alisporivir in humans. | 2015 | Clin Pharmacol Drug Dev | pmid:27128001 |
| Gomi K et al. | Full-mouth scaling and root planing combined with azithromycin to treat peri-implantitis. | 2015 | Aust Dent J | pmid:25439282 |
| Schroeck JL et al. | Factors associated with antibiotic misuse in outpatient treatment for upper respiratory tract infections. | 2015 | Antimicrob. Agents Chemother. | pmid:25870064 |
| Zhi D et al. | The enhancement of cardiac toxicity by concomitant administration of Berberine and macrolides. | 2015 | Eur J Pharm Sci | pmid:25976224 |
| Verleden GM et al. | Current views on chronic rejection after lung transplantation. | 2015 | Transpl. Int. | pmid:25857869 |
| Singh AE et al. | Gonorrhea Treatment Failures With Oral and Injectable Expanded Spectrum Cephalosporin Monotherapy vs Dual Therapy at 4 Canadian Sexually Transmitted Infection Clinics, 2010-2013. | 2015 | Sex Transm Dis | pmid:25970311 |
| Waites KB et al. | In vitro antibacterial activity of AZD0914 against human Mycoplasmas and Ureaplasmas. | 2015 | Antimicrob. Agents Chemother. | pmid:25824220 |
| Unemo M et al. | Five-day Azithromycin Treatment Regimen for Mycoplasma genitalium Infection Also Effectively Eradicates Chlamydia trachomatis. | 2015 | Acta Derm. Venereol. | pmid:25823977 |
| Nakamura M et al. | Cat-scratch disease presenting as a solitary splenic abscess in an elderly man. | 2015 | BMJ Case Rep | pmid:25804947 |
| Baker KS et al. | Intercontinental dissemination of azithromycin-resistant shigellosis through sexual transmission: a cross-sectional study. | 2015 | Lancet Infect Dis | pmid:25936611 |
| Phelan VV et al. | Mass Spectrometry Analysis of Pseudomonas aeruginosa Treated with Azithromycin. | 2015 | J. Am. Soc. Mass Spectrom. | pmid:25801585 |
| Agaisse H | Shigella flexneri serotype 3a: the rise of a superbug. | 2015 | Lancet Infect Dis | pmid:25936610 |
| Jimenez V et al. | Mass drug administration for trachoma: how long is not long enough? | 2015 | PLoS Negl Trop Dis | pmid:25799168 |
| Kitsiouli E et al. | Effect of azithromycin on the LPS-induced production and secretion of phospholipase A2 in lung cells. | 2015 | Biochim. Biophys. Acta | pmid:25791017 |
| Prohl A et al. | Enrofloxacin and macrolides alone or in combination with rifampicin as antimicrobial treatment in a bovine model of acute Chlamydia psittaci infection. | 2015 | PLoS ONE | pmid:25768665 |
| Coolen N et al. | Reduced risk of nontuberculous mycobacteria in cystic fibrosis adults receiving long-term azithromycin. | 2015 | J. Cyst. Fibros. | pmid:25735458 |
| Soares GM et al. | Effects of azithromycin, metronidazole, amoxicillin, and metronidazole plus amoxicillin on an in vitro polymicrobial subgingival biofilm model. | 2015 | Antimicrob. Agents Chemother. | pmid:25733510 |
| Parry CM et al. | Clinically and microbiologically derived azithromycin susceptibility breakpoints for Salmonella enterica serovars Typhi and Paratyphi A. | 2015 | Antimicrob. Agents Chemother. | pmid:25733500 |
| Shoaib A et al. | Determining the role of a probiotic in the restoration of intestinal microbial balance by molecular and cultural techniques. | 2015 | Genet. Mol. Res. | pmid:25730092 |
| Corris PA et al. | A randomised controlled trial of azithromycin therapy in bronchiolitis obliterans syndrome (BOS) post lung transplantation. | 2015 | Thorax | pmid:25714615 |