Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

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Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Otitis Media, Suppurative D010035 4 associated lipids
Yaws D015001 4 associated lipids
Psittacosis D009956 4 associated lipids
Lymphangitis D008205 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Acinetobacter Infections D000151 4 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Vertigo D014717 4 associated lipids
Meningoencephalitis D008590 4 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Urethral Diseases D014522 4 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Chancroid D002602 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Tick Infestations D013984 4 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Respiratory Tract Infections D012141 4 associated lipids
Parasitemia D018512 5 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Dog Diseases D004283 5 associated lipids
Lyme Disease D008193 5 associated lipids
Splenic Diseases D013158 5 associated lipids
Prostatitis D011472 5 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Rickettsia Infections D012282 5 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Protozoan Infections D011528 6 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Bronchiolitis D001988 6 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Syphilis D013587 6 associated lipids
Whooping Cough D014917 6 associated lipids
Skin Ulcer D012883 6 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Bonnet M and Van der Auwera P Preincubation of Haemophilus influenzae with subinhibitory concentrations of macrolides: influence on human neutrophil chemiluminescence. 1993 Antimicrob. Agents Chemother. pmid:8390808
Gordillo ME et al. In vitro activity of azithromycin against bacterial enteric pathogens. 1993 Antimicrob. Agents Chemother. pmid:8390813
Blais J et al. Inhibition of Toxoplasma gondii protein synthesis by azithromycin. 1993 Antimicrob. Agents Chemother. pmid:8215287
Dever LL et al. Comparative in vitro activities of clarithromycin, azithromycin, and erythromycin against Borrelia burgdorferi. 1993 Antimicrob. Agents Chemother. pmid:8215288
Weiss LM et al. Efficacy of azithromycin for treating Babesia microti infection in the hamster model. 1993 J. Infect. Dis. pmid:8228366
Agacfidan A et al. In vitro activity of azithromycin (CP-62,993) against Chlamydia trachomatis and Chlamydia pneumoniae. 1993 Antimicrob. Agents Chemother. pmid:8239579
Tomazic J et al. In vivo administration of azithromycin affects lymphocyte activity in vitro. 1993 Antimicrob. Agents Chemother. pmid:8239585
Cantin L and Chamberland S In vitro evaluation of the activities of azithromycin alone and combined with pyrimethamine against Toxoplasma gondii. 1993 Antimicrob. Agents Chemother. pmid:8239619
Rodewald LE and Pichichero ME Compliance with antibiotic therapy: a comparison of deuterium oxide tracer, urine bioassay, bottle weights, and parental reports. 1993 J. Pediatr. pmid:8391566
Vargas SL et al. Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancer. 1993 J. Pediatr. pmid:8391567