Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

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Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Vertigo D014717 4 associated lipids
Meningoencephalitis D008590 4 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Urethral Diseases D014522 4 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Chancroid D002602 4 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Tick Infestations D013984 4 associated lipids
Respiratory Tract Infections D012141 4 associated lipids
Retinitis D012173 4 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Eyelid Diseases D005141 4 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Yaws D015001 4 associated lipids
Psittacosis D009956 4 associated lipids
Dog Diseases D004283 5 associated lipids
Lyme Disease D008193 5 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Splenic Diseases D013158 5 associated lipids
Prostatitis D011472 5 associated lipids
Rickettsia Infections D012282 5 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Parasitemia D018512 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Bronchiolitis D001988 6 associated lipids
Syphilis D013587 6 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Whooping Cough D014917 6 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Skin Ulcer D012883 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Protozoan Infections D011528 6 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Serum Sickness D012713 7 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Azithromycin and OIs. 1996 AIDS Patient Care STDS pmid:11361699
[The treatment of sexually transmitted diseases in pregnant women with sumamed]. 2005 Akush Ginekol (Sofiia) pmid:16544724
Sirakov M and Ivanov S [Sumamed--efficacy and convenience]. 2005 Akush Ginekol (Sofiia) pmid:16028403
Museva A et al. [Participation of the genital mycoplasmas: Ureaplasma urealyticum and Mycoplasma hominis in the processes of preterm birth]. 2007 Akush Ginekol (Sofiia) pmid:19705693
Damianov L et al. [Treatment of genital chlamydia infections with Sumamed]. 2001 Akush Ginekol (Sofiia) pmid:11519320
Nikolov A et al. [Application of sumamed in treatment of bacterial vaginal infections during pregnancy]. 2008 Akush Ginekol (Sofiia) pmid:18756825
Nalbanski B and Nalbanski A [Treatment of Chlamydia trachomatis with azatril]. 2002 Akush Ginekol (Sofiia) pmid:11935692
Krumov G et al. [Treatment of chlamydial cervicitis with azatril]. 2002 Akush Ginekol (Sofiia) pmid:11935693
Borisov I [A new therapeutic approach in the treatment of genital chlamydial infections. Azithromycin (Sumamed)]. 1998 Akush Ginekol (Sofiia) pmid:10204275
Preheim LC et al. Ethanol feeding does not affect the efficacy or pharmacokinetics of azithromycin, trovafloxacin, or ceftriaxone in a rat model of pneumococcal pneumonia. 1999 Alcohol. Clin. Exp. Res. pmid:10371404
Tindberg Y et al. Helicobacter pylori eradication in children and adolescents by a once daily 6-day treatment with or without a proton pump inhibitor in a double-blind randomized trial. 2004 Aliment. Pharmacol. Ther. pmid:15274666
Chey WD et al. Low- versus high-dose azithromycin triple therapy for Helicobacter pylori infection. 1998 Aliment. Pharmacol. Ther. pmid:9882036
Trevisani L et al. Evaluation of a new ultrashort triple therapy for Helicobacter pylori disease. 1998 Aliment. Pharmacol. Ther. pmid:9882037
Calabrese C et al. Pantoprazole, azithromycin and tinidazole: short duration triple therapy for eradication of Helicobacter pylori infection. 2000 Aliment. Pharmacol. Ther. pmid:11121909
Laurent J et al. A randomized comparison of four omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. 2001 Aliment. Pharmacol. Ther. pmid:11683693
Katelaris PH et al. Activity of metronidazole, azithromycin and three benzimidazoles on Giardia lamblia growth and attachment to a human intestinal cell line. 1994 Aliment. Pharmacol. Ther. pmid:8038350
Cammarota G et al. Helicobacter pylori eradication using one-week low-dose lansoprazole plus amoxycillin and either clarithromycin or azithromycin. 1996 Aliment. Pharmacol. Ther. pmid:8971300
Pilotto A et al. Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers. 1996 Aliment. Pharmacol. Ther. pmid:8971305
Vcev A et al. Pantoprazole, amoxycillin and either azithromycin or clarithromycin for eradication of Helicobacter pylori in duodenal ulcer. 2000 Aliment. Pharmacol. Ther. pmid:10632647
Vcev A et al. Omeprazole, azithromycin and either amoxycillin or metronidazole in eradication of Helicobacter pylori in duodenal ulcer patients. 1998 Aliment. Pharmacol. Ther. pmid:9663725