Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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See S | Is azithromycin monotherapy as efficacious as cefuroxime plus erythromycin for the treatment of community-acquired pneumonia in hospitalized patients? | 2000 | J Fam Pract | pmid:11052155 |
Renz CL and Ashraf T | Comment: cost-effectiveness of macrolides in lower respiratory tract infections. | 2000 | Ann Pharmacother | pmid:11054992 |
Boccazzi A et al. | Short course therapy with cefitbuten versus azithromycin in pediatric streptococcal pharyngitis. | 2000 | Pediatr. Infect. Dis. J. | pmid:11055597 |
Bayoumi AM and Redelmeier DA | Decision analysis with cumulative prospect theory. | 2000 Oct-Dec | Med Decis Making | pmid:11059473 |
Sader H and Del'Alamo L | Etest compared to broth microdilution: discrepant results when testing macrolides against Streptococcus pneumoniae indicate a need for better clinical and serum level/MIC correlation. | 2000 | Braz J Infect Dis | pmid:11063559 |
Frenck RW et al. | Azithromycin versus ceftriaxone for the treatment of uncomplicated typhoid fever in children. | 2000 | Clin. Infect. Dis. | pmid:11073741 |
Dunne M et al. | A randomized, double-blind trial comparing azithromycin and clarithromycin in the treatment of disseminated Mycobacterium avium infection in patients with human immunodeficiency virus. | 2000 | Clin. Infect. Dis. | pmid:11073759 |
Krause PJ et al. | Atovaquone and azithromycin for the treatment of babesiosis. | 2000 | N. Engl. J. Med. | pmid:11078770 |
Macaigne G et al. | [Acute pseudoangiocholitic hepatitis probably induced by azithromycin]. | 2000 | Gastroenterol. Clin. Biol. | pmid:11084438 |
Alvarez MP et al. | [Pharmacovigilance study of azithromycin tablets (500 mg) in the treatment of adult patients with respiratory tract infections]. | 2000 | Rev Esp Quimioter | pmid:11086281 |
Gandhi R et al. | Validated LC method for in-vitro analysis of azithromycin using electrochemical detection. | 2000 | J Pharm Biomed Anal | pmid:11095310 |
Bowman RJ et al. | Operational comparison of single-dose azithromycin and topical tetracycline for trachoma. | 2000 | Invest. Ophthalmol. Vis. Sci. | pmid:11095598 |
Nagai K et al. | In vitro development of resistance to ceftriaxone, cefprozil and azithromycin in Streptococcus pneumoniae. | 2000 | J. Antimicrob. Chemother. | pmid:11102409 |
Waterer GW et al. | Fatal pneumococcal pneumonia attributed to macrolide resistance and azithromycin monotherapy. | 2000 | Chest | pmid:11115489 |
Esposito S and Ascione T | Short-course treatment for acute tonsillopharyngitis. | 2000 | Int. J. Antimicrob. Agents | pmid:11118866 |
Rothstein NM et al. | Effect of azithromycin on murine arteriosclerosis exacerbated by Chlamydia pneumoniae. | 2001 | J. Infect. Dis. | pmid:11120929 |
Bermudez LE et al. | Activity of moxifloxacin by itself and in combination with ethambutol, rifabutin, and azithromycin in vitro and in vivo against Mycobacterium avium. | 2001 | Antimicrob. Agents Chemother. | pmid:11120969 |
Calabrese C et al. | Pantoprazole, azithromycin and tinidazole: short duration triple therapy for eradication of Helicobacter pylori infection. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121909 |
DeAbate CA et al. | The safety and efficacy of short course (5-day) moxifloxacin vs. azithromycin in the treatment of patients with acute exacerbation of chronic bronchitis. | 2000 | Respir Med | pmid:11127487 |
Fuchs PC et al. | Influence of variations in test methods on susceptibility of Haemophilus influenzae to ampicillin, azithromycin, clarithromycin, and telithromycin. | 2001 | J. Clin. Microbiol. | pmid:11136745 |