Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hypersensitivity, Delayed D006968 43 associated lipids
Hypotension D007022 41 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Inflammation D007249 119 associated lipids
Keratitis D007634 7 associated lipids
Keratosis D007642 9 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Leishmaniasis, Mucocutaneous D007897 1 associated lipids
Leprosy D007918 8 associated lipids
Long QT Syndrome D008133 10 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Lung Diseases, Parasitic D008174 2 associated lipids
Lyme Disease D008193 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Lymphangitis D008205 4 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Meningoencephalitis D008590 4 associated lipids
Mitral Valve Stenosis D008946 3 associated lipids
Multiple Myeloma D009101 13 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Myelitis, Transverse D009188 1 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Neutropenia D009503 15 associated lipids
Endophthalmitis D009877 12 associated lipids
Opportunistic Infections D009894 8 associated lipids
Psittacosis D009956 4 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Otitis Media D010033 12 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Pain D010146 64 associated lipids
Pain, Postoperative D010149 13 associated lipids
Pancreatitis D010195 10 associated lipids
Paratyphoid Fever D010284 1 associated lipids
Pemphigus D010392 3 associated lipids
Penile Diseases D010409 2 associated lipids
Peptic Ulcer D010437 19 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Pericoronitis D010497 2 associated lipids
Periodontitis D010518 22 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Ishida K et al. In vitro and in vivo activities of macrolides against Mycoplasma pneumoniae. 1994 Antimicrob. Agents Chemother. pmid:8031048
Dorrell L et al. Intravenous azithromycin as salvage therapy in a patient with Legionnaire's disease. 1994 Thorax pmid:8016806
Cazzola M et al. Evaluation of lung tissue and hilar lymph node concentrations of azithromycin. 1994 Int J Clin Pharmacol Ther pmid:8004364
Hughes WT et al. Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model. 1994 J. Infect. Dis. pmid:7930735
Sifrim D et al. Comparison of the effects of midecamycin acetate and azithromycin on gastrointestinal motility in man. 1994 Drugs Exp Clin Res pmid:7956719
Dumas JL et al. Evaluation of the efficacy of prolonged administration of azithromycin in a murine model of chronic toxoplasmosis. 1994 J. Antimicrob. Chemother. pmid:7961197
Rakita RM et al. Intracellular activity of azithromycin against bacterial enteric pathogens. 1994 Antimicrob. Agents Chemother. pmid:7810998
Steingrímsson O et al. Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men. 1994 Jan-Feb Sex Transm Dis pmid:8140488
Tyndall MW et al. Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. 1994 Jul-Aug Sex Transm Dis pmid:7974076
Lang R et al. Therapeutic effects of roxithromycin and azithromycin in experimental murine brucellosis. 1994 Jul-Aug Chemotherapy pmid:8082413
Handsfield HH et al. Multicenter trial of single-dose azithromycin vs. ceftriaxone in the treatment of uncomplicated gonorrhea. Azithromycin Gonorrhea Study Group. 1994 Mar-Apr Sex Transm Dis pmid:9071422
Sher AA et al. [Interactions in the system of copper ion-azalide (azithromycin)]. 1994 Sep-Oct Antibiot. Khimioter. pmid:7695446
Tribble D et al. Efficacy of azithromycin for typhoid fever. 1995 Clin. Infect. Dis. pmid:8645805
Strickman D et al. In vitro effectiveness of azithromycin against doxycycline-resistant and -susceptible strains of Rickettsia tsutsugamushi, etiologic agent of scrub typhus. 1995 Antimicrob. Agents Chemother. pmid:8585717
Kieserman SP et al. Streptococcal pharyngitis: alternative treatments. 1995 Ear Nose Throat J pmid:8536567
van Rijsoort-Vos JH et al. In-vitro activity of a new quinolone (CP-99,219) compared with ciprofloxacin, pefloxacin, azithromycin and penicillin against Neisseria gonorrhoeae. 1995 J. Antimicrob. Chemother. pmid:8537268
Tajima T et al. [Pharmacokinetic and clinical studies with azithromycin (fine granule) in the pediatric field. Pediatric Study Group of Azithromycin]. 1995 Jpn J Antibiot pmid:7474329
al-Assi MT et al. Azithromycin triple therapy for Helicobacter pylori infection: azithromycin, tetracycline, and bismuth. 1995 Am. J. Gastroenterol. pmid:7872278
Wawer MJ et al. AIDS intervention in Uganda. 1995 Science pmid:7570005
Van Asselt GJ et al. Susceptibility of Streptococcus pyogenes to azithromycin, clarithromycin, erythromycin and roxithromycin in vitro. 1995 J. Med. Microbiol. pmid:7563004