Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Odenholt-Tornqvist I et al. | Postantibiotic effects and postantibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens. | 1995 | Antimicrob. Agents Chemother. | pmid:7695310 |
Malinverni R et al. | Effects of two antibiotic regimens on course and persistence of experimental Chlamydia pneumoniae TWAR pneumonitis. | 1995 | Antimicrob. Agents Chemother. | pmid:7695327 |
Hunter RP et al. | Pharmacokinetics, oral bioavailability and tissue distribution of azithromycin in cats. | 1995 | J. Vet. Pharmacol. Ther. | pmid:7752305 |
Ives DV et al. | Impact of clarithromycin and azithromycin on patterns of treatment and survival among AIDS patients with disseminated Mycobacterium avium complex. | 1995 | AIDS | pmid:7755914 |
Onyeji CO et al. | Activities of clarithromycin, azithromycin, and ofloxacin in combination with liposomal or unencapsulated granulocyte-macrophage colony-stimulating factor against intramacrophage Mycobacterium avium-Mycobacterium intracellulare. | 1995 | J. Infect. Dis. | pmid:7658075 |
Lo KK et al. | An open non-comparative pilot study with azithromycin in the treatment of non-gonococcal urethritis in the sexually transmitted disease clinics in Hong Kong. | 1995 | Ann. Acad. Med. Singap. | pmid:8849186 |
Edelstein PH | Review of azithromycin activity against Legionella spp. | 1995 | Pathol. Biol. | pmid:8539085 |
Oh YK et al. | Formulation and efficacy of liposome-encapsulated antibiotics for therapy of intracellular Mycobacterium avium infection. | 1995 | Antimicrob. Agents Chemother. | pmid:8540724 |
Clancy J et al. | Assays to detect and characterize synthetic agents that inhibit the ErmC methyltransferase. | 1995 | J. Antibiot. | pmid:8557568 |
Amsden GW | Macrolides versus azalides: a drug interaction update. | 1995 | Ann Pharmacother | pmid:8547740 |
Wahlstrom E et al. | Improvement in cyclosporine-associated gingival hyperplasia with azithromycin therapy. | 1995 | N. Engl. J. Med. | pmid:7854392 |
Harris S et al. | Azithromycin and terfenadine: lack of drug interaction. | 1995 | Clin. Pharmacol. Ther. | pmid:7554704 |
Bokemeyer B | [Combined therapy with azithromycin and omeprazole for the eradication of Helicobacter pylori]. | 1995 | Dtsch. Med. Wochenschr. | pmid:7555645 |
Péc J et al. | [Treatment of chlamydia infections and a brief review of the problems]. | 1995 | Bratisl Lek Listy | pmid:7633932 |
Bowden FJ et al. | Azithromycin and syphilis. | 1995 | Genitourin Med | pmid:7635501 |
Rizzato G et al. | Efficacy of a three day course of azithromycin in moderately severe community-acquired pneumonia. | 1995 | Eur. Respir. J. | pmid:7789484 |
Pascual A et al. | Factors affecting the intracellular accumulation and activity of azithromycin. | 1995 | J. Antimicrob. Chemother. | pmid:7768786 |
Beghi G et al. | Efficacy and tolerability of azithromycin versus amoxicillin/clavulanic acid in acute purulent exacerbation of chronic bronchitis. | 1995 | J Chemother | pmid:7666122 |
[New ways of antibiotic therapy]. | 1995 | Internist (Berl) | pmid:9431354 | |
Bessette RE and Amsden GW | Treatment of non-HIV cryptosporidial diarrhea with azithromycin. | 1995 | Ann Pharmacother | pmid:8845560 |