Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Stein GE and Schooley S | Comparative serum bactericidal activity of clarithromycin and azithromycin against macrolide-sensitive and resistant strains of Streptococcus pneumoniae. | 2001 | Diagn. Microbiol. Infect. Dis. | pmid:11337186 |
Griffith DE et al. | Azithromycin-containing regimens for treatment of Mycobacterium avium complex lung disease. | 2001 | Clin. Infect. Dis. | pmid:11340525 |
Tan JS et al. | Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila. | 2001 | Clin. Infect. Dis. | pmid:11340527 |
Westfall DS et al. | Inoculation of two genotypes of Hemobartonella felis (California and Ohio variants) to induce infection in cats and the response to treatment with azithromycin. | 2001 | Am. J. Vet. Res. | pmid:11341386 |
Bowden FJ et al. | Azithromycin and pelvic inflammatory disease in the Northern Territory. | 2001 | Med. J. Aust. | pmid:11346115 |
Akritopoulou-Zanze I and Sowin TJ | Solid-phase synthesis of macrolide analogues. | 2001 May-Jun | J Comb Chem | pmid:11350254 |
Littler WA | Clindamycin suspension and endocarditis prophylaxis. | 2001 | Br Dent J | pmid:11352383 |
Tateda K et al. | Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa. | 2001 | Antimicrob. Agents Chemother. | pmid:11353657 |
Dinos GP et al. | Insights into the mechanism of azithromycin interaction with an Escherichia coli functional ribosomal complex. | 2001 | Mol. Pharmacol. | pmid:11353804 |
St Clair EW et al. | The effects of intravenous doxycycline therapy for rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial. | 2001 | Arthritis Rheum. | pmid:11357896 |
Kaplan EL et al. | Macrolide therapy of group A streptococcal pharyngitis: 10 days of macrolide therapy (clarithromycin) is more effective in streptococcal eradication than 5 days (azithromycin). | 2001 | Clin. Infect. Dis. | pmid:11360224 |
Fang X et al. | [Inhibitory activity of azithromycin on biofilm synthesis and synergism between azithromycin and fleroxacin on Pseudomonas aeruginosa in biofilms]. | 1998 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11360505 |
Clearance to market azithromycin as prevention for a common OI in advanced AIDS. | 1996 | AIDS Patient Care STDS | pmid:11361535 | |
Prophylactic antibiotic receives speedy FDA approval to reduce MAC disease in advanced HIV. | 1996 | AIDS Patient Care STDS | pmid:11361569 | |
Azithromycin and OIs. | 1996 | AIDS Patient Care STDS | pmid:11361699 | |
Benson C | Advances in the diagnosis and treatment of Mycobacterium avium complex (MAC) disease. | 1994 | AIDS Patient Care | pmid:11362136 |
What's in the water? | 1995 Mar-Apr | Treat Rev | pmid:11362299 | |
Rifabutin for MAC questioned. | 1995 Jul-Aug | Posit Aware | pmid:11362571 | |
Cheng B | Advances in prevention and treatment of MAC. | 1995 | PI Perspect | pmid:11363104 |
Prescott LM | Macrolides, azalides, and streptogrammins. | 1996 | J Int Assoc Physicians AIDS Care | pmid:11363516 |