Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Splenic Diseases D013158 5 associated lipids
Skin Ulcer D012883 6 associated lipids
Skin Neoplasms D012878 12 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Sinusitis D012852 9 associated lipids
Shock, Septic D012772 11 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Serum Sickness D012713 7 associated lipids
Scrub Typhus D012612 3 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Sarcoidosis D012507 13 associated lipids
Rosacea D012393 13 associated lipids
Rickettsia Infections D012282 5 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Retinitis D012173 4 associated lipids
Retinal Hemorrhage D012166 3 associated lipids
Respiratory Tract Infections D012141 4 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Psychomotor Agitation D011595 3 associated lipids
Psoriasis D011565 47 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Protozoan Infections D011528 6 associated lipids
Prostatitis D011472 5 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Periodontitis D010518 22 associated lipids
Pericoronitis D010497 2 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Peptic Ulcer D010437 19 associated lipids
Penile Diseases D010409 2 associated lipids
Pemphigus D010392 3 associated lipids
Paratyphoid Fever D010284 1 associated lipids
Pancreatitis D010195 10 associated lipids
Pain, Postoperative D010149 13 associated lipids
Pain D010146 64 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Otitis Media D010033 12 associated lipids
Osteomyelitis D010019 10 associated lipids
Osteitis D010000 10 associated lipids
Psittacosis D009956 4 associated lipids
Opportunistic Infections D009894 8 associated lipids
Endophthalmitis D009877 12 associated lipids
Neutropenia D009503 15 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Kwun WH et al. Effect of azithromycin in the treartment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. 2003 Transplant. Proc. pmid:12591416
Puig JM et al. Treatment of gingival hyperplasia secondary to cyclosporine by the new macrolide azithromycin. 1997 Transplant. Proc. pmid:9270772
Wirnsberger GH et al. Effect of antibiotic treatment with azithromycin on cyclosporine A-induced gingival hyperplasia among renal transplant recipients. 1998 Transplant. Proc. pmid:9723411
Tokgöz B et al. Effects of azithromycin on cyclosporine-induced gingival hyperplasia in renal transplant patients. 2004 Transplant. Proc. pmid:15621128
Lendermon EA et al. Azithromycin Fails to Prevent Accelerated Airway Obliteration in T-bet Mouse Lung Allograft Recipients. 2018 Transplant. Proc. pmid:29880387
Nash MM and Zaltzman JS Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. 1998 Transplantation pmid:9665078
Verleden GM and Dupont LJ Azithromycin therapy for patients with bronchiolitis obliterans syndrome after lung transplantation. 2004 Transplantation pmid:15167610
Imai N et al. A case of Campylobacter enteritis in a renal transplant recipient. 2013 Transplantation pmid:23774778
Vos R et al. Anti-inflammatory and immunomodulatory properties of azithromycin involved in treatment and prevention of chronic lung allograft rejection. 2012 Transplantation pmid:22461039
Gottlieb J et al. Long-term azithromycin for bronchiolitis obliterans syndrome after lung transplantation. 2008 Transplantation pmid:18192909
Verleden SE et al. Bronchiolitis obliterans syndrome and restrictive allograft syndrome: do risk factors differ? 2013 Transplantation pmid:23425818
Wirnsberger GH and Pfragner R Comment on "Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients" by Nash and Zaltzman. 1999 Transplantation pmid:10342326
Requena-Méndez A et al. Enteric fever in Barcelona: Changing patterns of importation and antibiotic resistance. Travel Med Infect Dis pmid:27890811
Dave J et al. Trends in antibiotic susceptibility of enteric fever isolates in East London. Travel Med Infect Dis pmid:25964222
Baneke A Review: Targeting trachoma: Strategies to reduce the leading infectious cause of blindness. 2012 Travel Med Infect Dis pmid:22326056
Swanson RN et al. Once-daily azithromycin for 3 days compared with clarithromycin for 10 days for acute exacerbation of chronic bronchitis: a multicenter, double-blind, randomized study. 2005 Treat Respir Med pmid:15725048
Cymbala AA et al. The disease-modifying effects of twice-weekly oral azithromycin in patients with bronchiectasis. 2005 Treat Respir Med pmid:15813663
Zervos M et al. Comparative efficacies and tolerabilities of intravenous azithromycin plus ceftriaxone and intravenous levofloxacin with step-down oral therapy for hospitalized patients with moderate to severe community-acquired pneumonia. 2004 Treat Respir Med pmid:15606222
What's in the water? 1995 Mar-Apr Treat Rev pmid:11362299
Azithro once a week for MAC. 1998 TreatmentUpdate pmid:11365625