Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Retinal Hemorrhage D012166 3 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Dyspnea D004417 10 associated lipids
Angina, Unstable D000789 14 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Keratitis D007634 7 associated lipids
Stevens-Johnson Syndrome D013262 3 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Lymphadenitis D008199 8 associated lipids
Drug Eruptions D003875 30 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Amebiasis D000562 2 associated lipids
Lung Diseases, Parasitic D008174 2 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Tooth Mobility D014086 2 associated lipids
Mitral Valve Stenosis D008946 3 associated lipids
Prostatitis D011472 5 associated lipids
Meningoencephalitis D008590 4 associated lipids
Cat Diseases D002371 12 associated lipids
Stomatitis D013280 14 associated lipids
Weight Loss D015431 56 associated lipids
Tendinopathy D052256 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Opportunistic Infections D009894 8 associated lipids
Acute Lung Injury D055371 33 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Keratosis D007642 9 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Rosacea D012393 13 associated lipids
Parasitemia D018512 5 associated lipids
Long QT Syndrome D008133 10 associated lipids
Gonorrhea D006069 7 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Haemophilus Infections D006192 3 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Helicobacter Infections D016481 21 associated lipids
Psychomotor Agitation D011595 3 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Mucositis D052016 7 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Mesa FL et al. Antibiotic treatment of incipient drug-induced gingival overgrowth in adult renal transplant patients. 2003 J. Periodont. Res. pmid:12608908
[Uncomplicated community-acquired pneumonia. Under control in 3 treatment days]. 2003 MMW Fortschr Med pmid:12619240
Arreaza L et al. Emergence of gonococcal strains with resistance to azithromycin in Spain. 2003 J. Antimicrob. Chemother. pmid:12493814
Schriever C et al. Red wine, resveratrol, Chlamydia pneumoniae and the French connection. 2003 Atherosclerosis pmid:14644410
Schillinger JA et al. Patient-delivered partner treatment with azithromycin to prevent repeated Chlamydia trachomatis infection among women: a randomized, controlled trial. 2003 Sex Transm Dis pmid:12514443
Jennings MB et al. Comparison of azithromycin and cefadroxil for the treatment of uncomplicated skin and skin structure infections. 2003 Cutis pmid:14533837
Callaghan R and Allen M Mycobacterium malmoense infection of the knee. 2003 Ann. Rheum. Dis. pmid:14583565
Niederman MS [Conservative use of antibiotics is important, but: "Resistance hysteria is exaggerated"]. 2003 MMW Fortschr Med pmid:14584217
Cotter CJ and Bierne JC Azithromycin for odontogenic infection. 2003 J. Oral Maxillofac. Surg. pmid:14586869
Al-Belasy FA and Hairam AR The efficacy of azithromycin in the treatment of acute infraorbital space infection. 2003 J. Oral Maxillofac. Surg. pmid:12618970
Rush C and Simon MW The effect of amoxicillin-clavulanate, cefixime and azithromycin on normal throat flora in children with group A streptococcal pharyngitis. 2003 Clin Pediatr (Phila) pmid:12862350
Lildholdt T et al. The natural history of recurrent acute tonsillitis and a clinical trial of azithromycin for antibiotic prophylaxis. 2003 Clin Otolaryngol Allied Sci pmid:12871256
Gologan R et al. Multiple myeloma in remission complicated by bone marrow granulomas. 2003 Rom J Intern Med pmid:15526516
Kogan R et al. Comparative randomized trial of azithromycin versus erythromycin and amoxicillin for treatment of community-acquired pneumonia in children. 2003 Pediatr. Pulmonol. pmid:12526069
Crum NF et al. Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. 2003 Am J Prev Med pmid:12880877
Gribajcević M et al. [Clinical effectiveness of omeprazole, azithromycin and amoxicillin in ulcer healing and eradication of Helicobacter pylori infection]. 2003 Med Arh pmid:15137249
Bhattacharya MK et al. Azithromycin in the treatment of cholera in children. 2003 Acta Paediatr. pmid:12856976
Saiman L et al. Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial. 2003 JAMA pmid:14519709
Danesi R et al. Comparative distribution of azithromycin in lung tissue of patients given oral daily doses of 500 and 1000 mg. 2003 J. Antimicrob. Chemother. pmid:12654753
Zhanel GG et al. Pharmacodynamic activity of azithromycin against macrolide-susceptible and -resistant Streptococcus pneumoniae simulating clinically achievable free serum, epithelial lining fluid and middle ear fluid concentrations. 2003 J. Antimicrob. Chemother. pmid:12775677
Blandford JM and Gift TL The cost-effectiveness of single-dose azithromycin for treatment of incubating syphilis. 2003 Sex Transm Dis pmid:12782951
Abdelghaffar H et al. Interaction of macrolides and ketolides with the phagocytic cell line PLB-985. 2003 J Chemother pmid:12962363
Miguel L and Barbas C LC determination of impurities in azithromycin tablets. 2003 J Pharm Biomed Anal pmid:12972086
Sirinavin S et al. Norfloxacin and azithromycin for treatment of nontyphoidal salmonella carriers. 2003 Clin. Infect. Dis. pmid:12942401
Matsuzaki K et al. [Susceptibility of major pathogens of acute pharyngitis and tonsillitis to levofloxacin and other oral antimicrobial drugs]. 2003 Jpn J Antibiot pmid:12942788
DeÄŸerli K et al. Efficacy of azithromycin in a murine toxoplasmosis model, employing a Toxoplasma gondii strain from Turkey. 2003 Acta Trop. pmid:12943976
Rocha JL Correct dose of azithromycin for patients scheduled to undergo dental procedures. 2003 Clin. Infect. Dis. pmid:12955653
Castaldo RS et al. A comparison of 5-day courses of dirithromycin and azithromycin in the treatment of acute exacerbations of chronic obstructive pulmonary disease. 2003 Clin Ther pmid:12749513
Skerk V et al. Comparative analysis of azithromycin and ciprofloxacin in the treatment of chronic prostatitis caused by Chlamydia trachomatis. 2003 Int. J. Antimicrob. Agents pmid:12727080
Trad O et al. Eradication of Cryptosporidium in four children with acute lymphoblastic leukemia. 2003 J. Trop. Pediatr. pmid:12729299
Zhou WQ et al. [Clinic efficacy of treating chronic prostatitis caused by Neisseria gonorrhoeae with azithromycin aspartic-acid injection]. 2003 Zhonghua Nan Ke Xue pmid:12680331
Sicklinger M et al. In vitro susceptibility testing of four antibiotics against Borrelia burgdorferi: a comparison of results for the three genospecies Borrelia afzelii, Borrelia garinii, and Borrelia burgdorferi sensu stricto. 2003 J. Clin. Microbiol. pmid:12682190
Karlowsky JA et al. Factors associated with relative rates of antimicrobial resistance among Streptococcus pneumoniae in the United States: results from the TRUST Surveillance Program (1998-2002). 2003 Clin. Infect. Dis. pmid:12684907
Hamdan II Comparative in vitro investigations of the interaction between some macrolides and Cu(II), Zn(II) and Fe(II). 2003 Pharmazie pmid:12685822
Llor Vilà C [I'd rather give azithromycin for three days. That way the patient complies]. 2003 Aten Primaria pmid:12735886
Gaynor BD et al. Eliminating trachoma in areas with limited disease. 2003 Emerging Infect. Dis. pmid:12737745
Ioannidis J and Wilkinson D HIV: prevention of opportunistic infections. 2003 Clin Evid pmid:15555123
Woods GL et al. Multisite reproducibility of results obtained by two broth dilution methods for susceptibility testing of Mycobacterium avium complex. 2003 J. Clin. Microbiol. pmid:12574258
Aznabaev MT et al. [Use of cycloferon in a combined treatment of chlamydial conjunctivitis]. 2003 Jan-Feb Vestn Oftalmol pmid:12608044
Scheinfeld NS et al. Macrolides in dermatology. 2003 Jan-Feb Clin. Dermatol. pmid:12609587
Bevan CD et al. Efficacy and safety of azithromycin as monotherapy or combined with metronidazole compared with two standard multidrug regimens for the treatment of acute pelvic inflammatory disease. 2003 Jan-Feb J. Int. Med. Res. pmid:12635534
Prata A et al. Efficacy of azithromycin in the treatment of cutaneous leishmaniasis. 2003 Jan-Feb Rev. Soc. Bras. Med. Trop. pmid:12715065
Knuf M et al. [Lymphadenitis colli due to non-tuberculous mycobacteria (NTM): a case-series and review of the literature]. 2003 Jan-Feb Klin Padiatr pmid:12545419
Bernstein JM The farmer and the tractor. 2003 Mar-Apr Skinmed pmid:14673307
Aktan B et al. Effect of macrolide antibiotics on nitric oxide synthase and xanthine oxidase activities, and malondialdehyde level in erythrocyte of the guinea pigs with experimental otitis media with effusion. 2003 Nov-Dec Pol J Pharmacol pmid:14730107
Khandekarf R and Mohammed AJ Outcome of azithromycin treatment of active trachoma in Omani school children. 2003 Sep-Nov East. Mediterr. Health J. pmid:16450533
Wyrick PB and Knight ST Pre-exposure of infected human endometrial epithelial cells to penicillin in vitro renders Chlamydia trachomatis refractory to azithromycin. 2004 J. Antimicrob. Chemother. pmid:15163653
Agmon I et al. Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism. 2004 FEBS Lett. pmid:15165888
Verleden GM and Dupont LJ Azithromycin therapy for patients with bronchiolitis obliterans syndrome after lung transplantation. 2004 Transplantation pmid:15167610
Davies G and Wilson R Prophylactic antibiotic treatment of bronchiectasis with azithromycin. 2004 Thorax pmid:15170047
Peeling RW and Mabey DC Syphilis. 2004 Nat. Rev. Microbiol. pmid:15181902
Hammerschlag MR and Roblin PM The in vitro activity of a new fluoroquinolone, ABT-492, against recent clinical isolates of Chlamydia pneumoniae. 2004 J. Antimicrob. Chemother. pmid:15190026
Ranque S et al. In vitro activity of azithromycin and dirithromycin against axenic Entamoeba histolytica. 2004 Eur. J. Clin. Microbiol. Infect. Dis. pmid:15599659
Ngan CC et al. Susceptibility testing of Singapore strains of Mycoplasma hominis to tetracycline, gatifloxacin, moxifloxacin, ciprofloxacin, clindamycin, and azithromycin by the Etest method. 2004 Diagn. Microbiol. Infect. Dis. pmid:15023431
Máiz Carro L and Cantón Moreno R [Azithromycin therapy in cystic fibrosis]. 2004 Med Clin (Barc) pmid:15030744
Baumann U et al. Long term azithromycin therapy in cystic fibrosis patients: a study on drug levels and sputum properties. 2004 Can. Respir. J. pmid:15045047
Ables AZ and Warren PK High-dose azithromycin or amoxicillin-clavulanate for recurrent otitis media? 2004 J Fam Pract pmid:15000920
Capitano B et al. Steady-state intrapulmonary concentrations of moxifloxacin, levofloxacin, and azithromycin in older adults. 2004 Chest pmid:15006955
Abe T et al. [A case of Q fever infection causing acute exacerbation of chronic respiratory failure]. 2004 Nihon Kokyuki Gakkai Zasshi pmid:15007923
Skerk V et al. Azithromycin: 4.5- or 6.0-gram dose in the treatment of patients with chronic prostatitis caused by Chlamydia trachomatis--a randomized study. 2004 J Chemother pmid:15332719
AltintaÅŸ E et al. Comparison of ranitidine bismuth citrate, tetracycline and metronidazole with ranitidine bismuth citrate and azithromycin for the eradication of Helicobacter pylori in patients resistant to PPI based triple therapy. 2004 Turk J Gastroenterol pmid:15334317
Koeth LM et al. Streptococcus pneumoniae in vitro development of resistance to amoxicillin/clavulanic acid, cefaclor, levofloxacin and azithromycin. 2004 Int. J. Antimicrob. Agents pmid:15288313
Rahav G et al. Azithromycin versus comparative therapy for the treatment of community acquired pneumonia. 2004 Int. J. Antimicrob. Agents pmid:15288319
Skerk V et al. Comparative randomized pilot study of azithromycin and doxycycline efficacy in the treatment of prostate infection caused by Chlamydia trachomatis. 2004 Int. J. Antimicrob. Agents pmid:15288321
Lever MS et al. In vitro susceptibility of Coxiella burnetii to azithromycin, doxycycline, ciprofloxacin and a range of newer fluoroquinolones. 2004 Int. J. Antimicrob. Agents pmid:15288324
Addy LD and Martin MV Azithromycin and dentistry - a useful agent? 2004 Br Dent J pmid:15311248
Marrie TJ Experience with levofloxacin in a critical pathway for the treatment of community-acquired pneumonia. 2004 Chemotherapy pmid:15319549
Nielsen HU et al. Nasopharyngeal pathogens in children with acute otitis media in a low-antibiotic use country. 2004 Int. J. Pediatr. Otorhinolaryngol. pmid:15302145
Brian SR and Kimbrough RC Salvage of a prosthetic knee joint infected with resistant pneumococcus. A case report. 2004 J Bone Joint Surg Am pmid:15466745
Sugie M et al. Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin. 2004 Antimicrob. Agents Chemother. pmid:14982769
Kim YS et al. A comparative trial of a single dose of azithromycin versus doxycycline for the treatment of mild scrub typhus. 2004 Clin. Infect. Dis. pmid:15494910
Panpanich R et al. Azithromycin for acute lower respiratory tract infections. 2004 Cochrane Database Syst Rev pmid:15497172
Koytchev R et al. Assessment of the bioequivalence of different formulations containing azithromycin (tablets and suspension). 2004 Arzneimittelforschung pmid:15497663
Tindberg Y et al. Helicobacter pylori eradication in children and adolescents by a once daily 6-day treatment with or without a proton pump inhibitor in a double-blind randomized trial. 2004 Aliment. Pharmacol. Ther. pmid:15274666
Katz E et al. Safety and efficacy of sequential i.v. to p.o. moxifloxacin versus conventional combination therapies for the treatment of community-acquired pneumonia in patients requiring initial i.v. therapy. 2004 J Emerg Med pmid:15498622
Halpern MT and Cifaldi MA Is azithromycin the first-choice macrolide for treatment of community-acquired pneumonia? 2004 Clin. Infect. Dis. pmid:15206068
Gordon EM and Blumer JL Rationale for single and high dose treatment regimens with azithromycin. 2004 Pediatr. Infect. Dis. J. pmid:14770072
Carr RR and Nahata MC Azithromycin for improving pulmonary function in cystic fibrosis. 2004 Ann Pharmacother pmid:15213312
Arguedas A et al. Single dose azithromycin for the treatment of uncomplicated otitis media. 2004 Pediatr. Infect. Dis. J. pmid:14770073
Clyti E et al. [Short treatment of donovanosis with azithromycin]. 2004 Ann Dermatol Venereol pmid:15235534
Arrieta A and Singh J Management of recurrent and persistent acute otitis media: new options with familiar antibiotics. 2004 Pediatr. Infect. Dis. J. pmid:14770074
Snider LA and Swedo SE PANDAS: current status and directions for research. 2004 Mol. Psychiatry pmid:15241433
Cohen R Defining the optimum treatment regimen for azithromycin in acute tonsillopharyngitis. 2004 Pediatr. Infect. Dis. J. pmid:14770076
Jacobs MR et al. Study design questions in treatment of children with acute otitis media. 2004 Antimicrob. Agents Chemother. pmid:15241848
Ruuskanen O Safety and tolerability of azithromycin in pediatric infectious diseases: 2003 update. 2004 Pediatr. Infect. Dis. J. pmid:14770077
Klein JO and Schaad UB [Use of azithromycin in the treatment of acute otitis media and tonsillopharyngitis: summary and conclusions. 2004 Pediatr. Infect. Dis. J. pmid:14770078
Langley JM et al. Azithromycin is as effective as and better tolerated than erythromycin estolate for the treatment of pertussis. 2004 Pediatrics pmid:15231980
Hunfeld KP et al. New real-time PCR-based method for in vitro susceptibility testing of Anaplasma phagocytophilum against antimicrobial agents. 2004 Int. J. Antimicrob. Agents pmid:15194126
Michot JM et al. Active efflux of ciprofloxacin from J774 macrophages through an MRP-like transporter. 2004 Antimicrob. Agents Chemother. pmid:15215125
Hoberman A and Paradise JL Study design questions in treatment of children with acute otitis media. 2004 Antimicrob. Agents Chemother. pmid:15215151
Miron D et al. Azithromycin as an alternative to nalidixic acid in the therapy of childhood shigellosis. 2004 Pediatr. Infect. Dis. J. pmid:15071299
Palcevski G et al. Antibiotic use profile at paediatric clinics in two transitional countries. 2004 Pharmacoepidemiol Drug Saf pmid:15072118
Gross M et al. Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor. 2004 J. Antimicrob. Chemother. pmid:14963065
Gandhi R et al. Pharmacokinetic evaluation of an azithromycin controlled release dosage form in healthy human volunteers: a single dose study. 2004 Int J Pharm pmid:14726116
Liao CH et al. Nutritionally variant streptococcal infections at a University Hospital in Taiwan: disease emergence and high prevalence of beta-lactam and macrolide resistance. 2004 Clin. Infect. Dis. pmid:14727223
Levy SB et al. The misuse of antibiotics. 2004 Med Ethics (Burlingt Mass) pmid:15915579
Low N Chlamydia (uncomplicated, genital). 2004 Clin Evid pmid:15865780
Le Normand Y et al. [An example of simulation for a better understanding of PK/PD relationship of antibiotics]. 2004 Pathol. Biol. pmid:15596309
Mueller M et al. Toll-like receptors 2 and 4 do not contribute to clearance of Chlamydophila pneumoniae in mice, but are necessary for the release of monokines. 2004 Immunobiology pmid:15638128
Jones S et al. The tip of the iceberg: opportunistic screening for Chlamydia trachomatis in asymptomatic patients attending a young people's health clinic reveals a high prevalence--a pilot study. 2004 Sex Health pmid:16334993