Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nicolau DP et al. | Beneficial effect of adjunctive azithromycin in treatment of mucoid Pseudomonas aeruginosa pneumonia in the murine model. | 1999 | Antimicrob. Agents Chemother. | pmid:10582906 |
| Shanks GD et al. | Single dose of azithromycin or three-day course of ciprofloxacin as therapy for epidemic dysentery in Kenya. Acute Dysentery Study Group. | 1999 | Clin. Infect. Dis. | pmid:10589921 |
| Sendi PP et al. | Cost-effectiveness of azithromycin for preventing Mycobacterium avium complex infection in HIV-positive patients in the era of highly active antiretroviral therapy. The Swiss HIV Cohort Study. | 1999 | J. Antimicrob. Chemother. | pmid:10590283 |
| Grimes DA and Schulz KF | Prophylactic antibiotics for intrauterine device insertion: a metaanalysis of the randomized controlled trials. | 1999 | Contraception | pmid:10592851 |
| Dagan R et al. | Bacteriologic efficacies of oral azithromycin and oral cefaclor in treatment of acute otitis media in infants and young children. | 2000 | Antimicrob. Agents Chemother. | pmid:10602721 |
| Ianaro A et al. | Anti-inflammatory activity of macrolide antibiotics. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10604943 |
| Bowden FJ and Skov SJ | Treating donovanosis. | 1999 | Aust Fam Physician | pmid:10615749 |
| National guideline for the management of donovanosis (granuloma inguinale). Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616381 | |
| Burgess DS et al. | A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. | 1999 | Ann Pharmacother | pmid:10630825 |
| Puri SK and Singh N | Azithromycin: antimalarial profile against blood- and sporozoite-induced infections in mice and monkeys. | 2000 | Exp. Parasitol. | pmid:10631075 |
| Vcev A et al. | Pantoprazole, amoxycillin and either azithromycin or clarithromycin for eradication of Helicobacter pylori in duodenal ulcer. | 2000 | Aliment. Pharmacol. Ther. | pmid:10632647 |
| Karpov OI | [The clinical and economic efficacies of short courses of azithromycin in acute sinusitis]. | 1999 | Antibiot. Khimioter. | pmid:10635419 |
| Morita JY et al. | Impact of azithromycin on oropharyngeal carriage of group A Streptococcus and nasopharyngeal carriage of macrolide-resistant Streptococcus pneumoniae. | 2000 | Pediatr. Infect. Dis. J. | pmid:10643849 |
| Fernandez-Obregon AC | Azithromycin for the treatment of acne. | 2000 | Int. J. Dermatol. | pmid:10651967 |
| Steen R et al. | Evidence of declining STD prevalence in a South African mining community following a core-group intervention. | 2000 | Sex Transm Dis | pmid:10654860 |
| Lo SH et al. | Azithromycin-induced hearing loss. | 1999 | Am J Health Syst Pharm | pmid:10690220 |
| Giacometti A et al. | Efficacy of treatment with paromomycin, azithromycin, and nitazoxanide in a patient with disseminated cryptosporidiosis. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10691200 |
| Dagan R et al. | Bacteriologic and clinical efficacy of amoxicillin/clavulanate vs. azithromycin in acute otitis media. | 2000 | Pediatr. Infect. Dis. J. | pmid:10693993 |
| Bowden FJ et al. | Donovanosis causing cervical lymphadenopathy in a five-month-old boy. | 2000 | Pediatr. Infect. Dis. J. | pmid:10694010 |
| Giacometti A et al. | Anticryptosporidial activity of ranalexin, lasalocid and azithromycin alone and in combination in cell lines. | 2000 | J. Antimicrob. Chemother. | pmid:10702561 |
| Slavinsky J et al. | Factors associated with the decline in sexually transmitted infections among HIV-positive women. | 2000 | J. Acquir. Immune Defic. Syndr. | pmid:10708065 |
| Angelilli ML et al. | Palatability of oral antibiotics among children in an urban primary care center. | 2000 | Arch Pediatr Adolesc Med | pmid:10710025 |
| Rino BE et al. | Azithromycin in the treatment of plasmodium falciparum gametocytes: a preliminary observation. | 2000 | J. Trop. Pediatr. | pmid:10730047 |
| Canut Blasco A et al. | [A randomized, prospective and comparative study is a clinical trial]. | 2000 | Med Clin (Barc) | pmid:10734631 |
| Potts JM et al. | Association of chronic urinary symptoms in women and Ureaplasma urealyticum. | 2000 | Urology | pmid:10736488 |
| Ouchi K | Chlamydia pneumoniae and atherosclerosis. | 1999 | Jpn. J. Infect. Dis. | pmid:10738358 |
| Schissel DJ et al. | Azithromycin eruption in infectious mononucleosis: a proposed mechanism of interaction. | 2000 | Cutis | pmid:10738636 |
| Giacometti A et al. | Activity of nitazoxanide alone and in combination with azithromycin and rifabutin against Cryptosporidium parvum in cell culture. | 2000 | J. Antimicrob. Chemother. | pmid:10747821 |
| Nishi Y et al. | [Effect of macrolide antibiotics on adhesion by cancer cells]. | 2000 | Jpn J Antibiot | pmid:10756450 |
| Wenisch C | [Pharmacokinetic effects of antibiotics on the development of bacterial resistance particularly in reference to azithromycin]. | 2000 | Wien Med Wochenschr | pmid:10756595 |
| Diculencu D et al. | [The postantibiotic effect of azithromycin on respiratory pathogens]. | 1998 Jul-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:10756861 |
| Somani J et al. | Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure. | 2000 | J. Infect. Dis. | pmid:10762573 |
| El-Sadr WM et al. | Discontinuation of prophylaxis for Mycobacterium avium complex disease in HIV-infected patients who have a response to antiretroviral therapy. Terry Beirn Community Programs for Clinical Research on AIDS. | 2000 | N. Engl. J. Med. | pmid:10766581 |
| Brieland JK et al. | Efficacy of SCH27899 in an animal model of Legionnaires' disease using immunocompromised A/J mice. | 2000 | Antimicrob. Agents Chemother. | pmid:10770771 |
| Najib MM et al. | Cost-effectiveness of sparfloxacin compared with other oral antimicrobials in outpatient treatment of community-acquired pneumonia. | 2000 | Pharmacotherapy | pmid:10772376 |
| Laming AC et al. | A targeted, single-dose azithromycin strategy for trachoma. | 2000 | Med. J. Aust. | pmid:10772587 |
| Donders GG | Treatment of sexually transmitted bacterial diseases in pregnant women. | 2000 | Drugs | pmid:10776830 |
| Bujanda L et al. | Ranitidine bismuth citrate plus azithromycin for Helicobacter pylori eradication. | 2000 | J. Clin. Gastroenterol. | pmid:10777206 |
| Ress BD and Gross EM | Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. | 2000 | Ann. Otol. Rhinol. Laryngol. | pmid:10778901 |
| Miller SA et al. | Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human vascular smooth muscle and induces cellular proliferation. | 2000 | J. Surg. Res. | pmid:10781378 |
| Skerk V et al. | Comparative analysis of azithromycin and doxycycline efficacy in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum. | 2000 | J Chemother | pmid:10789560 |
| Kozyrskyj AL et al. | Short course antibiotics for acute otitis media. | 2000 | Cochrane Database Syst Rev | pmid:10796591 |
| Sasaki TY and Sumida KN | Angioimmunoblastic T-cell lymphoma (AIL-TCL) following macrolide administration. | 2000 | Hawaii Med J | pmid:10800250 |
| Vergis EN et al. | Azithromycin vs cefuroxime plus erythromycin for empirical treatment of community-acquired pneumonia in hospitalized patients: a prospective, randomized, multicenter trial. | 2000 | Arch. Intern. Med. | pmid:10809032 |
| Turcinov D et al. | Failure of azithromycin in treatment of Brill-Zinsser disease. | 2000 | Antimicrob. Agents Chemother. | pmid:10817744 |
| Tsitsika A et al. | Single-oral-dose azithromycin prophylaxis against experimental streptococcal or staphylococcal aortic valve endocarditis. | 2000 | Antimicrob. Agents Chemother. | pmid:10817749 |
| Bin XX et al. | Effect of azithromycin plus rifampin versus amoxicillin alone on eradication and inflammation in the chronic course of Chlamydia pneumoniae pneumonitis in mice. | 2000 | Antimicrob. Agents Chemother. | pmid:10817751 |
| Zuckerman JM | The newer macrolides: azithromycin and clarithromycin. | 2000 | Infect. Dis. Clin. North Am. | pmid:10829265 |
| Mirmiran R et al. | Disseminated gonococcal infection: a case of beta-lactamase-producing Neisseria gonorrhoeae. | 2000 | J Am Podiatr Med Assoc | pmid:10833879 |
| Straubinger RK | PCR-Based quantification of Borrelia burgdorferi organisms in canine tissues over a 500-Day postinfection period. | 2000 | J. Clin. Microbiol. | pmid:10834975 |
| Moshkani SK and Dalimi A | Evaluation of the efficacy of atovaquone alone or in combination with azithromycin against acute murine toxoplasmosis. | 2000 | Vet. Res. Commun. | pmid:10836275 |
| Matute AJ et al. | Is a 5 day course of azithromycin enough for infections caused by Legionella pneumophila? | 2000 | J. Antimicrob. Chemother. | pmid:10837459 |
| Anderson JL and Muhlestein JB | The ACADEMIC study in perspective (Azithromycin in coronary artery disease: elimination of myocardial infection with Chlamydia). | 2000 | J. Infect. Dis. | pmid:10839761 |
| Dunne MW | Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trial. | 2000 | J. Infect. Dis. | pmid:10839762 |
| Jackson LA | Description and status of the azithromycin and coronary events study (ACES). | 2000 | J. Infect. Dis. | pmid:10839763 |
| Heikkinen T et al. | The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin. | 2000 | BJOG | pmid:10847234 |
| Raja Babu KK et al. | Confluent and reticulate papillomatosis: successful treatment with azithromycin. | 2000 | Br. J. Dermatol. | pmid:10848767 |
| Ernst EJ et al. | Comparison of the serum and intracellular pharmacokinetics of azithromycin in healthy and diabetic volunteers. | 2000 | Pharmacotherapy | pmid:10853621 |
| Criqui GI et al. | Effects of azithromycin on ozone-induced airway neutrophilia and cytokine release. | 2000 | Eur. Respir. J. | pmid:10853849 |
| Plouffe J et al. | Clinical efficacy of intravenous followed by oral azithromycin monotherapy in hospitalized patients with community-acquired pneumonia. The Azithromycin Intravenous Clinical Trials Group. | 2000 | Antimicrob. Agents Chemother. | pmid:10858333 |
| Chinh NT et al. | A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. | 2000 | Antimicrob. Agents Chemother. | pmid:10858343 |
| Miltner EC and Bermudez LE | Mycobacterium avium grown in Acanthamoeba castellanii is protected from the effects of antimicrobials. | 2000 | Antimicrob. Agents Chemother. | pmid:10858369 |
| SendaÄŸ F et al. | Single dose oral azithromycin versus seven day doxycycline in the treatment of non-gonococcal mucopurulent endocervicitis. | 2000 | Aust N Z J Obstet Gynaecol | pmid:10870778 |
| Scharfstein JA et al. | The cost-effectiveness of prophylaxis for Mycobacterium avium complex in AIDS. | 1999 | Int J Technol Assess Health Care | pmid:10874380 |
| Gruber F et al. | Treatment of early syphilis with azithromycin. | 2000 | J Chemother | pmid:10877520 |
| Barsic B et al. | Comparison of azithromycin and doxycycline in the treatment of erythema migrans. | 2000 May-Jun | Infection | pmid:10879639 |
| Koch CC et al. | Apoptosis, oxidative metabolism and interleukin-8 production in human neutrophils exposed to azithromycin: effects of Streptococcus pneumoniae. | 2000 | J. Antimicrob. Chemother. | pmid:10882684 |
| Herrera D et al. | The periodontal abscess (II). Short-term clinical and microbiological efficacy of 2 systemic antibiotic regimes. | 2000 | J. Clin. Periodontol. | pmid:10883868 |
| McBroom JW | Medical management of interstitial pregnancy with a retained IUD. A case report. | 2000 | J Reprod Med | pmid:10900583 |
| Drugs for sexually transmitted infections. | 1999 | Med Lett Drugs Ther | pmid:10906932 | |
| Gomperts BN and White LK | Gonococcal hand abscess. | 2000 | Pediatr. Infect. Dis. J. | pmid:10917235 |
| Hammerschlag MR | Treatment of Chlamydia pneumoniae. | 2000 | Int. J. Antimicrob. Agents | pmid:10926449 |
| Rekart M et al. | Mass treatment/prophylaxis during an outbreak of infectious syphilis in Vancouver, British Columbia. | 2000 | Can. Commun. Dis. Rep. | pmid:10932390 |
| Ng DK et al. | A randomized controlled trial of azithromycin and amoxycillin/clavulanate in the management of subacute childhood rhinosinusitis. | 2000 | J Paediatr Child Health | pmid:10940175 |
| Vranes J | Effect of subminimal inhibitory concentrations of azithromycin on adherence of Pseudomonas aeruginosa to polystyrene. | 2000 | J Chemother | pmid:10949976 |
| Dean D et al. | Evidence for long-term cervical persistence of Chlamydia trachomatis by omp1 genotyping. | 2000 | J. Infect. Dis. | pmid:10950788 |
| Mandell GL and Coleman EJ | Activities of antimicrobial agents against intracellular pneumococci. | 2000 | Antimicrob. Agents Chemother. | pmid:10952618 |
| Thompson C | Azithromycin v oxytetracycline for the treatment of non-specific urethritis. | 2000 | Sex Transm Infect | pmid:10961211 |
| Scaglione F et al. | In vitro comparative dynamics of modified-release clarithromycin and of azithromycin. | 2000 Sep-Oct | Chemotherapy | pmid:10965100 |
| Guzey M et al. | Three-day course of oral azithromycin vs topical oxytetracycline/polymyxin in treatment of active endemic trachoma. | 2000 Jul-Aug | Jpn. J. Ophthalmol. | pmid:10974295 |
| Jonas D et al. | The effect of azithromycin on intracellular Legionella pneumophila in the Mono Mac 6 cell line at serum concentrations attainable in vivo. | 2000 | J. Antimicrob. Chemother. | pmid:10980164 |
| Schouenborg P et al. | Azithromycin versus pivampicillin in the treatment of acute exacerbations of chronic bronchitis: a single-blind, double-dummy, multicentre study. | 2000 May-Jun | J. Int. Med. Res. | pmid:10983860 |
| Fogarty C et al. | Bacteremic pneumonia due to multidrug-resistant pneumococci in 3 patients treated unsuccessfully with azithromycin and successfully with levofloxacin. | 2000 | Clin. Infect. Dis. | pmid:10987733 |
| Ohtani H et al. | Comparative pharmacodynamic analysis of Q-T interval prolongation induced by the macrolides clarithromycin, roxithromycin, and azithromycin in rats. | 2000 | Antimicrob. Agents Chemother. | pmid:10991836 |
| Beckey NP et al. | Retrospective evaluation of a potential interaction between azithromycine and warfarin in patients stabilized on warfarin. | 2000 | Pharmacotherapy | pmid:10999497 |
| Flores S et al. | [Triple therapy of short-term with azithromycin, amoxycillin and omeprazole for the eradication of Helicobacter pylori]. | 2000 | Rev Med Chil | pmid:11008354 |
| Fluoroquinolone-resistance in Neisseria gonorrhoeae, Hawaii, 1999, and decreased susceptibility to azithromycin in N. gonorrhoeae, Missouri, 1999. | 2000 | MMWR Morb. Mortal. Wkly. Rep. | pmid:11012233 | |
| Erhardt W et al. | Establishing criteria for assessment of efficacy of antimicrobial agents in acute otitis media. | 2000 | Antimicrob. Agents Chemother. | pmid:11012390 |
| Westphal JF | Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin. | 2000 | Br J Clin Pharmacol | pmid:11012550 |
| Currier JS et al. | Discontinuation of Mycobacterium avium complex prophylaxis in patients with antiretroviral therapy-induced increases in CD4+ cell count. A randomized, double-blind, placebo-controlled trial. AIDS Clinical Trials Group 362 Study Team. | 2000 | Ann. Intern. Med. | pmid:11015162 |
| Schneider CA et al. | In vivo uptake of azithromycin in human coronary plaques. | 2000 | Am. J. Cardiol. | pmid:11018204 |
| Kuper JI and D'Aprile M | Drug-Drug interactions of clinical significance in the treatment of patients with Mycobacterium avium complex disease. | 2000 | Clin Pharmacokinet | pmid:11020135 |
| Grayston JT | Secondary prevention antibiotic treatment trials for coronary artery disease. | 2000 | Circulation | pmid:11023925 |
| Muhlestein JB et al. | Randomized secondary prevention trial of azithromycin in patients with coronary artery disease: primary clinical results of the ACADEMIC study. | 2000 | Circulation | pmid:11023928 |
| Granowitz EV et al. | Potentially fatal interaction between azithromycin and disopyramide. | 2000 | Pacing Clin Electrophysiol | pmid:11025903 |
| Semaan HB et al. | The effect of chronic azithromycin therapy on soluble endothelium-derived adhesion molecules in patients with coronary artery disease. | 2000 | J. Cardiovasc. Pharmacol. | pmid:11026657 |
| Miller JM and Martin DH | Treatment of Chlamydia trachomatis infections in pregnant women. | 2000 | Drugs | pmid:11030469 |
| Ghaffar F et al. | Effects of amoxicillin/clavulanate or azithromycin on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae in children with acute otitis media. | 2000 | Clin. Infect. Dis. | pmid:11049764 |
| Kelley MA et al. | Breakthrough pneumococcal bacteremia in patients being treated with azithromycin and clarithromycin. | 2000 | Clin. Infect. Dis. | pmid:11049784 |
| Adachi JA et al. | Empirical antimicrobial therapy for traveler's diarrhea. | 2000 | Clin. Infect. Dis. | pmid:11049792 |