Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bailey RL et al. | Randomised controlled trial of single-dose azithromycin in treatment of trachoma. | 1993 | Lancet | pmid:8102427 |
| Donowitz GR and Earnhardt KI | Azithromycin inhibition of intracellular Legionella micdadei. | 1993 | Antimicrob. Agents Chemother. | pmid:8285604 |
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| Vaara M | Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. | 1993 | Antimicrob. Agents Chemother. | pmid:8383945 |
| Brown ST et al. | Azithromycin, rifabutin, and rifapentine for treatment and prophylaxis of Mycobacterium avium complex in rats treated with cyclosporine. | 1993 | Antimicrob. Agents Chemother. | pmid:8384809 |
| Hammerschlag MR et al. | Single dose of azithromycin for the treatment of genital chlamydial infections in adolescents. | 1993 | J. Pediatr. | pmid:8388950 |
| Melski JW et al. | Primary and secondary erythema migrans in central Wisconsin. | 1993 | Arch Dermatol | pmid:8389536 |
| Kobrehel G et al. | 9a,11-cyclic carbamates of 15-membered azalides. | 1993 | J. Antibiot. | pmid:8407586 |
| Bonnet M and Van der Auwera P | Preincubation of Haemophilus influenzae with subinhibitory concentrations of macrolides: influence on human neutrophil chemiluminescence. | 1993 | Antimicrob. Agents Chemother. | pmid:8390808 |
| Gordillo ME et al. | In vitro activity of azithromycin against bacterial enteric pathogens. | 1993 | Antimicrob. Agents Chemother. | pmid:8390813 |
| Amacher DE et al. | Preclinical toxicology studies with azithromycin: genetic toxicology evaluation. | 1993 | Mutat. Res. | pmid:7685497 |
| Blais J et al. | Inhibition of Toxoplasma gondii protein synthesis by azithromycin. | 1993 | Antimicrob. Agents Chemother. | pmid:8215287 |
| Dever LL et al. | Comparative in vitro activities of clarithromycin, azithromycin, and erythromycin against Borrelia burgdorferi. | 1993 | Antimicrob. Agents Chemother. | pmid:8215288 |
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| Fass RJ | Erythromycin, clarithromycin, and azithromycin: use of frequency distribution curves, scattergrams, and regression analyses to compare in vitro activities and describe cross-resistance. | 1993 | Antimicrob. Agents Chemother. | pmid:8257127 |
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| Pajukanta R | In vitro antimicrobial susceptibility of Porphyromonas gingivalis to azithromycin, a novel macrolide. | 1993 | Oral Microbiol. Immunol. | pmid:8265209 |
| Gage TW | New drugs from 1991-1992. | 1993 | Tex Dent J | pmid:8273018 |
| Spangler SK and Appelbaum PC | Oxyrase, a method which avoids CO2 in the incubation atmosphere for anaerobic susceptibility testing of antibiotics affected by CO2. | 1993 | J. Clin. Microbiol. | pmid:8381817 |
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| de Górgolas Hernández-Mora M et al. | [Therapeutic approaches to cryptosporidiosis. A review of the literature]. | 1993 | Rev Clin Esp | pmid:8259458 |
| Vargas SL et al. | Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancer. | 1993 | J. Pediatr. | pmid:8391567 |
| Berger BW | Lyme disease. | 1993 | Semin Dermatol | pmid:8312152 |
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| Gingras BA and Jensen JB | Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. | 1993 | Am. J. Trop. Med. Hyg. | pmid:8394660 |
| Mansoor GA et al. | Azithromycin-induced acute interstitial nephritis. | 1993 | Ann. Intern. Med. | pmid:8395778 |
| Guerra LG et al. | Rapid response of AIDS-related bacillary angiomatosis to azithromycin. | 1993 | Clin. Infect. Dis. | pmid:8399879 |
| Workowski KA et al. | Azithromycin in chlamydial urethritis. | 1993 | JAMA | pmid:8411548 |
| Genç M et al. | An economic evaluation of screening for Chlamydia trachomatis in adolescent males. | 1993 | JAMA | pmid:8411572 |
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| Odugbemi T et al. | Single oral dose of azithromycin for therapy of susceptible sexually transmitted diseases: a multicenter open evaluation. | 1993 Jul-Sep | West Afr J Med | pmid:8312208 |
| Minguez F et al. | In vitro killing kinetics and postantibiotic effect of josamycin and other macrolides on several bacteria. | 1993 May-Jun | Chemotherapy | pmid:8389685 |
| Weber K et al. | Azithromycin versus penicillin V for the treatment of early Lyme borreliosis. | 1993 Nov-Dec | Infection | pmid:8132365 |
| Scaglione F et al. | A new model examining intracellular and extracellular activity of amoxicillin, azithromycin, and clarithromycin in infected cells. | 1993 Nov-Dec | Chemotherapy | pmid:8222870 |
| Braga PC and Piatti G | Interference by subinhibitory concentrations of azithromycin with the mechanism of bacterial adhesion to human epithelial cells. | 1993 Nov-Dec | Chemotherapy | pmid:8222872 |
| Goldman MP and Longworth DL | The role of azithromycin and clarithromycin in clinical practice. | 1993 Sep-Oct | Cleve Clin J Med | pmid:8403355 |
| Benson C | Advances in the diagnosis and treatment of Mycobacterium avium complex (MAC) disease. | 1994 | AIDS Patient Care | pmid:11362136 |
| O'Day DM et al. | Ocular pharmacokinetics of orally administered azithromycin in rabbits. | 1994 | J Ocul Pharmacol | pmid:7714407 |
| Ishida K et al. | In vitro and in vivo activities of macrolides against Mycoplasma pneumoniae. | 1994 | Antimicrob. Agents Chemother. | pmid:8031048 |
| Tuffrey M et al. | The effect of a single oral dose of azithromycin on chlamydial infertility and oviduct ultrastructure in mice. | 1994 | J. Antimicrob. Chemother. | pmid:7730241 |
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| Klepser ME et al. | Treatment of uncomplicated infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae. | 1994 | Conn Med | pmid:7924316 |
| Wallace MR et al. | Ototoxicity with azithromycin. | 1994 | Lancet | pmid:7904701 |
| Klemens SP and Cynamon MH | Intermittent azithromycin for treatment of Mycobacterium avium infection in beige mice. | 1994 | Antimicrob. Agents Chemother. | pmid:7986001 |
| Donowitz GR | Tissue-directed antibiotics and intracellular parasites: complex interaction of phagocytes, pathogens, and drugs. | 1994 | Clin. Infect. Dis. | pmid:7893881 |
| Andersen SL et al. | Efficacy of azithromycin as a causal prophylactic agent against murine malaria. | 1994 | Antimicrob. Agents Chemother. | pmid:7986022 |
| Beale AS and Upshon PA | Characteristics of murine model of genital infection with Chlamydia trachomatis and effects of therapy with tetracyclines, amoxicillin-clavulanic acid, or azithromycin. | 1994 | Antimicrob. Agents Chemother. | pmid:7811001 |
| Verdon MS et al. | Pilot study of azithromycin for treatment of primary and secondary syphilis. | 1994 | Clin. Infect. Dis. | pmid:7811868 |
| Cazzola M et al. | Evaluation of lung tissue and hilar lymph node concentrations of azithromycin. | 1994 | Int J Clin Pharmacol Ther | pmid:8004364 |
| Raszka WV et al. | Multifocal M. intracellulare osteomyelitis in an immunocompetent child. | 1994 | Clin Pediatr (Phila) | pmid:7813141 |
| Hughes WT et al. | Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model. | 1994 | J. Infect. Dis. | pmid:7930735 |
| Rehg JE | A comparison of anticryptosporidial activity of paromomycin with that of other aminoglycosides and azithromycin in immunosuppressed rats. | 1994 | J. Infect. Dis. | pmid:7930738 |
| Spangler SK et al. | Effect of CO2 on susceptibilities of anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin. | 1994 | Antimicrob. Agents Chemother. | pmid:8192445 |
| Niki Y et al. | In vitro and in vivo activities of azithromycin, a new azalide antibiotic, against chlamydia. | 1994 | Antimicrob. Agents Chemother. | pmid:7840560 |
| Stamler DA et al. | Azithromycin pharmacokinetics and intracellular concentrations in Legionella pneumophila-infected and uninfected guinea pigs and their alveolar macrophages. | 1994 | Antimicrob. Agents Chemother. | pmid:8192446 |
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| Management of genital Chlamydia trachomatis infections. | 1994 | Drug Ther Bull | pmid:7635012 | |
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| [Newly approved specialty drugs in Austria and new knowledge about currently available specialty drugs. Zithromax capsules, dried syrup]. | 1994 | Wien. Klin. Wochenschr. | pmid:7975673 | |
| Cynamon MH et al. | Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice. | 1994 | Antimicrob. Agents Chemother. | pmid:7979270 |
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| Pfefferkorn ER and Borotz SE | Comparison of mutants of Toxoplasma gondii selected for resistance to azithromycin, spiramycin, or clindamycin. | 1994 | Antimicrob. Agents Chemother. | pmid:8141576 |
| Bermudez LE et al. | Rifabutin and sparfloxacin but not azithromycin inhibit binding of Mycobacterium avium complex to HT-29 intestinal mucosal cells. | 1994 | Antimicrob. Agents Chemother. | pmid:8067766 |
| Uzun O et al. | Efficacy of a three-day course of azithromycin in the treatment of community-acquired pneumococcal pneumonia. Preliminary report. | 1994 | J Chemother | pmid:8071680 |
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| Kuschner RA et al. | Azithromycin prophylaxis against a chloroquine-resistant strain of Plasmodium falciparum. | 1994 | Lancet | pmid:7910886 |
| Rakita RM et al. | Intracellular activity of azithromycin against bacterial enteric pathogens. | 1994 | Antimicrob. Agents Chemother. | pmid:7810998 |
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