Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Retinal Hemorrhage D012166 3 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Dyspnea D004417 10 associated lipids
Angina, Unstable D000789 14 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Keratitis D007634 7 associated lipids
Stevens-Johnson Syndrome D013262 3 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Lymphadenitis D008199 8 associated lipids
Drug Eruptions D003875 30 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Amebiasis D000562 2 associated lipids
Lung Diseases, Parasitic D008174 2 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Tooth Mobility D014086 2 associated lipids
Mitral Valve Stenosis D008946 3 associated lipids
Prostatitis D011472 5 associated lipids
Meningoencephalitis D008590 4 associated lipids
Cat Diseases D002371 12 associated lipids
Stomatitis D013280 14 associated lipids
Weight Loss D015431 56 associated lipids
Tendinopathy D052256 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Opportunistic Infections D009894 8 associated lipids
Acute Lung Injury D055371 33 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Keratosis D007642 9 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Rosacea D012393 13 associated lipids
Parasitemia D018512 5 associated lipids
Long QT Syndrome D008133 10 associated lipids
Gonorrhea D006069 7 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Haemophilus Infections D006192 3 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Helicobacter Infections D016481 21 associated lipids
Psychomotor Agitation D011595 3 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Mucositis D052016 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Speer EM et al. Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. 2018 PLoS ONE pmid:29715306
Chen QF and Zhang YW [Clinical effect of Saccharomyces boulardii powder combined with azithromycin sequential therapy in treatment of children with diarrhea secondary to Mycoplasma pneumoniae pneumonia]. 2018 Zhongguo Dang Dai Er Ke Za Zhi pmid:29429459
Bandyopadhyay R et al. Effectiveness of treatment regimens for Typhoid fever in the nalidixic acid-resistant S. typhi (NARST) era in South India. 2018 Trop Doct pmid:29495943
Mulugeta A et al. Coverage, social mobilization and challenges of mass Zithromax administration campaign in South and South East zones of Tigray, Northern Ethiopia: A cross sectional study. 2018 PLoS Negl Trop Dis pmid:29481558
Atkin PA and Simms ML Orofacial granulomatosis: an unsuccessful response to weekly azithromycin pulse therapy. 2018 Oral Surg Oral Med Oral Pathol Oral Radiol pmid:29477603
Li B et al. The efficacy of azithromycin and doxycycline treatment for rectal chlamydial infection: a retrospective cohort study in South Australia. 2018 Intern Med J pmid:28967178
Zikic A et al. Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis. 2018 J Pediatric Infect Dis Soc pmid:30007329
Balci O and Gulkilik G Assessment of efficacy of topical azithromycin 1.5 per cent ophthalmic solution for the treatment of meibomian gland dysfunction. 2018 Clin Exp Optom pmid:28677153
Lundin MS et al. Lemierre's syndrome and 2016 American College of Physician guidelines for pharyngitis: no to empiric coverage for bacterial pharyngitis. While no role for routine Fusobacterium PCR, keep suspicion for this pathogen. 2018 BMJ Case Rep pmid:30030249
Celma A et al. Development of a Retention Time Interpolation scale (RTi) for liquid chromatography coupled to mass spectrometry in both positive and negative ionization modes. 2018 J Chromatogr A pmid:30005941