Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Chodorowska M et al. [Susceptibility to macrolide antibiotics of Bordetella pertussis and Bordetella parapertussis strains isolated from whooping cough patients in 1968 and in 1997-99]. 2001 Med Dosw Mikrobiol pmid:11757403
Jacks S et al. Pharmacokinetics of azithromycin and concentration in body fluids and bronchoalveolar cells in foals. 2001 Am. J. Vet. Res. pmid:11763173
Bragina EY et al. Electron microscopic evidence of persistent chlamydial infection following treatment. 2001 J Eur Acad Dermatol Venereol pmid:11763379
Swanston WH et al. Single dose (direct observed) azithromycin therapy for Neisseria gonorrhoeae and Chlamydia trachomatis in STD clinic attenders with genital discharge in Trinidad and Tobago. 2001 West Indian Med J pmid:11769023
Phillips P et al. Azithromycin prophylaxis for Mycobacterium avium complex during the era of highly active antiretroviral therapy: evaluation of a provincial program. 2002 Clin. Infect. Dis. pmid:11774085
Mendes CM et al. In vitro susceptibility of gram-positive cocci isolated from skin and respiratory tract to azithromycin and twelve other antimicrobial agents. 2001 Braz J Infect Dis pmid:11779453
Castor D et al. Antibiotic resistant N. gonorrhoeae in Trinidad and Tobago. 2001 Cell. Mol. Biol. (Noisy-le-grand) pmid:11785665
Oksi J [Diagnostics and treatment of Lyme borreliosis]. 2000 Duodecim pmid:11787113
van der Griend B et al. An uncommon cause of a destructive vulval lesion. 2001 Aust N Z J Obstet Gynaecol pmid:11787928
Kutlin A et al. Effect of prolonged treatment with azithromycin, clarithromycin, or levofloxacin on Chlamydia pneumoniae in a continuous-infection Model. 2002 Antimicrob. Agents Chemother. pmid:11796350
Nagai K et al. Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries. 2002 Antimicrob. Agents Chemother. pmid:11796375
Skerk V et al. Azithromycin in the treatment of chronic prostatitis caused by Chlamydia trachomatis. 2001 J Chemother pmid:11806631
Stiefelhagen P [Treatment refractory fever... und then also the kidneys fail]. 2001 MMW Fortschr Med pmid:11808449
Tateda K et al. Potential of macrolide antibiotics to inhibit protein synthesis of Pseudomonas aeruginosa: suppression of virulence factors and stress response. 2000 J. Infect. Chemother. pmid:11810524
Andersen SE et al. [Failed azithromycin treatment of Chlamydia trachomatis infection]. 2001 Ugeskr. Laeg. pmid:11810790
Dawson CR and Schachter J Should trachoma be treated with antibiotics? 2002 Lancet pmid:11812548
Safak MA et al. A comparative study of azithromycin and pseudoephedrine hydrochloride for otitis media with effusion in children. 2001 Acta Otolaryngol. pmid:11813896
Zubata P et al. A new HPLC method for azithromycin quantitation. 2002 J Pharm Biomed Anal pmid:11814725
Lentino JR and Krasnicka B Association between initial empirical therapy and decreased length of stay among veteran patients hospitalized with community acquired pneumonia. 2002 Int. J. Antimicrob. Agents pmid:11814769
Vorbach H et al. Endothelial cell compatibility of azithromycin and erythromycin. 2002 J. Antimicrob. Chemother. pmid:11815590