Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Benson C Advances in the diagnosis and treatment of Mycobacterium avium complex (MAC) disease. 1994 AIDS Patient Care pmid:11362136
O'Day DM et al. Ocular pharmacokinetics of orally administered azithromycin in rabbits. 1994 J Ocul Pharmacol pmid:7714407
Ishida K et al. In vitro and in vivo activities of macrolides against Mycoplasma pneumoniae. 1994 Antimicrob. Agents Chemother. pmid:8031048
Tuffrey M et al. The effect of a single oral dose of azithromycin on chlamydial infertility and oviduct ultrastructure in mice. 1994 J. Antimicrob. Chemother. pmid:7730241
Dorrell L et al. Intravenous azithromycin as salvage therapy in a patient with Legionnaire's disease. 1994 Thorax pmid:8016806
Raszka WV et al. Multifocal M. intracellulare osteomyelitis in an immunocompetent child. 1994 Clin Pediatr (Phila) pmid:7813141
Niki Y et al. In vitro and in vivo activities of azithromycin, a new azalide antibiotic, against chlamydia. 1994 Antimicrob. Agents Chemother. pmid:7840560
Freeman CD et al. Intracellular and extracellular penetration of azithromycin into inflammatory and noninflammatory blister fluid. 1994 Antimicrob. Agents Chemother. pmid:7840585
Wildfeuer A et al. Distribution of orally administered azithromycin in various blood compartments. 1994 Int J Clin Pharmacol Ther pmid:7952797
Bottaro G et al. [Evaluation of the clinical efficacy of azithromycin in acute respiratory infections in children]. 1994 Clin Ter pmid:7955949
Sifrim D et al. Comparison of the effects of midecamycin acetate and azithromycin on gastrointestinal motility in man. 1994 Drugs Exp Clin Res pmid:7956719
Dumas JL et al. Evaluation of the efficacy of prolonged administration of azithromycin in a murine model of chronic toxoplasmosis. 1994 J. Antimicrob. Chemother. pmid:7961197
Carlier MB et al. Accumulation, release and subcellular localization of azithromycin in phagocytic and non-phagocytic cells in culture. 1994 Int J Tissue React pmid:7558665
Management of genital Chlamydia trachomatis infections. 1994 Drug Ther Bull pmid:7635012
Chiarini F et al. Chlamydia trachomatis genitourinary infections: laboratory diagnosis and therapeutic aspects. Evaluation of in vitro and in vivo effectiveness of azithromycin. 1994 J Chemother pmid:7830100
Pfefferkorn ER and Borotz SE Comparison of mutants of Toxoplasma gondii selected for resistance to azithromycin, spiramycin, or clindamycin. 1994 Antimicrob. Agents Chemother. pmid:8141576
Uzun O et al. Efficacy of a three-day course of azithromycin in the treatment of community-acquired pneumococcal pneumonia. Preliminary report. 1994 J Chemother pmid:8071680
Rakita RM et al. Intracellular activity of azithromycin against bacterial enteric pathogens. 1994 Antimicrob. Agents Chemother. pmid:7810998
Bermudez LE et al. Recombinant granulocyte-macrophage colony-stimulating factor enhances the effects of antibiotics against Mycobacterium avium complex infection in the beige mouse model. 1994 J. Infect. Dis. pmid:8158029
Rehg J New potential therapies for cryptosporidiosis: an analysis of variables affecting drug efficacy. 1994 Folia Parasitol. pmid:8050751