| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Genital Diseases, Male | D005832 | 3 associated lipids |
| Sexually Transmitted Diseases | D012749 | 4 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Abscess | D000038 | 13 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Misra R and Prasad KN | Antimicrobial susceptibility to azithromycin among Salmonella enterica Typhi and Paratyphi A isolates from India. | 2016 | J. Med. Microbiol. | pmid:27902389 |
| Paul SP et al. | Spontaneous surgical emphysema: an unusual complication of paediatric asthma. | 2016 | Br J Hosp Med (Lond) | pmid:27828753 |
| Serdar Kutuk M et al. | Relationship between maternal c-reactive protein level and neonatal outcome in patients with preterm premature rupture of membranes treated with Ampicillin and Azithromycin. | 2016 | J Obstet Gynaecol | pmid:27825282 |
| Ervin AM et al. | Surveillance and Azithromycin Treatment for Newcomers and Travelers Evaluation (ASANTE) Trial: Design and Baseline Characteristics. | 2016 | Ophthalmic Epidemiol | pmid:27820670 |
| Weintraub A et al. | In-vitro activity of solithromycin against anaerobic bacteria from the normal intestinal microbiota. | 2016 | Anaerobe | pmid:27725229 |
| Berkowitz ST et al. | Resolution of spontaneous hemoabdomen secondary to peliosis hepatis following surgery and azithromycin treatment in a Bartonella species infected dog. | 2016 | J Vet Emerg Crit Care (San Antonio) | pmid:27074964 |
| Wang A et al. | Effects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia. | 2016 | Sci Rep | pmid:27405358 |
| Menzel M et al. | Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients. | 2016 | Sci Rep | pmid:27350308 |
| O'Beirne SL et al. | Trust Your Instincts. Surgical Lung Biopsy with Normal Chest Imaging in a 49-Year-Old Man with Progressive Dyspnea. | 2016 | Ann Am Thorac Soc | pmid:27144798 |
| Mwingira UJ et al. | Progress of Trachoma Mapping in Mainland Tanzania: Results of Baseline Surveys from 2012 to 2014. | 2016 | Ophthalmic Epidemiol | pmid:27775455 |
| Wind CM et al. | Time to clearance of Chlamydia trachomatis RNA and DNA after treatment in patients coinfected with Neisseria gonorrhoeae - a prospective cohort study. | 2016 | BMC Infect. Dis. | pmid:27724878 |
| Yasuda M et al. | Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility of azithromycin and increase in the failure of azithromycin therapy in male gonococcal urethritis in Sendai in 2015. | 2016 | J. Infect. Chemother. | pmid:27578029 |
| Tita AT et al. | Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2016 | N. Engl. J. Med. | pmid:27682034 |
| Committee Opinion No. 645: Dual Therapy for Gonococcal Infections. | 2016 | Obstet Gynecol | pmid:27548425 | |
| Waites KB et al. | In Vitro Activities of Omadacycline (PTK 0796) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas. | 2016 | Antimicrob. Agents Chemother. | pmid:27671057 |
| Committee Opinion No. 645 Summary: Dual Therapy for Gonococcal Infections. | 2016 | Obstet Gynecol | pmid:27548417 | |
| Li S et al. | Two case reports: Whole genome sequencing of two clinical macrolide-resistant Mycoplasma pneumoniae isolates with different responses to azithromycin. | 2016 | Medicine (Baltimore) | pmid:27661056 |
| Mustapha NA et al. | Impact of different antibiotics on methane production using waste-activated sludge: mechanisms and microbial community dynamics. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27531514 |
| Brunner A et al. | Emerging azithromycin-resistance among the Neisseria gonorrhoeae strains isolated in Hungary. | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27646968 |
| Molini BJ et al. | Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains. | 2016 | Sex Transm Dis | pmid:27513385 |
| Regnath T et al. | Antimicrobial resistance of Neisseria gonorrhoeae isolates in south-west Germany, 2004 to 2015: increasing minimal inhibitory concentrations of tetracycline but no resistance to third-generation cephalosporins. | 2016 | Euro Surveill. | pmid:27632642 |
| Xiridou M et al. | Cost-Effectiveness of Dual Antimicrobial Therapy for Gonococcal Infections Among Men Who Have Sex With Men in the Netherlands. | 2016 | Sex Transm Dis | pmid:27513379 |
| Mitjà O et al. | Mass Treatment with Single-Dose Azithromycin for Yaws. | 2016 | N. Engl. J. Med. | pmid:27626525 |
| Cheng GS et al. | Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant. | 2016 | Ann Am Thorac Soc | pmid:27513368 |
| Kobuchi S et al. | Transport of Azithromycin into Extravascular Space in Rats. | 2016 | Antimicrob. Agents Chemother. | pmid:27600045 |
| Marks M et al. | Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma. | 2016 | PLoS Negl Trop Dis | pmid:27551787 |
| Samson C et al. | Long-term effects of azithromycin in patients with cystic fibrosis. | 2016 | Respir Med | pmid:27492507 |
| Akram FE et al. | A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27530257 |
| Horner PJ et al. | 2016 European guideline on the management of non-gonococcal urethritis. | 2016 | Int J STD AIDS | pmid:27147267 |
| Kreuter A and Wieland U | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144858 |
| GarcÃa-Quintanilla M et al. | Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii. | 2016 | Antimicrob. Agents Chemother. | pmid:27270288 |
| Schachter J | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144857 |
| Zhou QT et al. | How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder? | 2016 | AAPS J | pmid:27255350 |
| MUW researcher of the month Franz Ratzinger. | 2016 | Wien. Klin. Wochenschr. | pmid:27113348 | |
| Yuan ZF et al. | Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with Mycoplasma pneumoniae infection. | 2016 | BMC Infect. Dis. | pmid:27230114 |
| Kloepfer KM | Azithromycin may prevent severe respiratory-infection-induced wheezing. | 2016 | J. Pediatr. | pmid:27112084 |
| Liu Y et al. | Influence of Omega 3 and 6 Fatty Acids on Human Meibomian Gland Epithelial Cells. | 2016 | Cornea | pmid:27227397 |
| Noda AA et al. | First Report of the 23S rRNA Gene A2058G Point Mutation Associated With Macrolide Resistance in Treponema pallidum From Syphilis Patients in Cuba. | 2016 | Sex Transm Dis | pmid:27100771 |
| Haas AN et al. | Predictors of clinical outcomes after periodontal treatment of aggressive periodontitis: 12-month randomized trial. | 2016 | Braz Oral Res | pmid:27223128 |
| Itaqui SR et al. | In Vitro Synergism between Azithromycin or Terbinafine and Topical Antimicrobial Agents against Pythium insidiosum. | 2016 | Antimicrob. Agents Chemother. | pmid:27216049 |
| Wang Z and Meenach SA | Synthesis and Characterization of Nanocomposite Microparticles (nCmP) for the Treatment of Cystic Fibrosis-Related Infections. | 2016 | Pharm. Res. | pmid:27091030 |
| Phong NC et al. | In Vivo Efficacy and Tolerability of Artesunate-Azithromycin for the Treatment of Falciparum Malaria in Vietnam. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27215294 |
| Ab Rahman N et al. | Antibiotic prescribing in public and private practice: a cross-sectional study in primary care clinics in Malaysia. | 2016 | BMC Infect. Dis. | pmid:27188538 |
| Brown J et al. | Shigellosis: high rates of antibiotic resistance necessitate new treatment recommendations. | 2016 | Med. J. Aust. | pmid:27078594 |
| Ramaiah B et al. | High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice. | 2016 | Daru | pmid:27150818 |
| Rajabi O et al. | Topical liposomal azithromycin in the treatment of acute cutaneous leishmaniasis. | 2016 | Dermatol Ther | pmid:27073044 |
| Economopoulos KP et al. | Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase. | 2016 | Diabetes Obes Metab | pmid:26876427 |
| Kang JY et al. | Long-term azithromycin ameliorates not only airway inflammation but also remodeling in a murine model of chronic asthma. | 2016 | Pulm Pharmacol Ther | pmid:26778828 |
| Sridhar S et al. | High recurrence rate supports need for secondary prophylaxis in non-HIV patients with disseminated mycobacterium avium complex infection: a multi-center observational study. | 2016 | BMC Infect. Dis. | pmid:26861696 |
| Peters RP et al. | Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome. | 2016 | Sex Transm Dis | pmid:26760182 |
| Hodgson D et al. | The Effects of Azithromycin in Treatment-Resistant Cough: A Randomized, Double-Blind, Placebo-Controlled Trial. | 2016 | Chest | pmid:26836927 |
| Zheng Z et al. | Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. | 2016 | J. Antibiot. | pmid:27118243 |
| Gratrix J et al. | A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men. | 2016 | Sex Transm Dis | pmid:26760180 |
| Kumaraswamy M et al. | Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia. | 2016 | J. Antimicrob. Chemother. | pmid:26832758 |
| Arikan S et al. | Effect of Topically Applied Azithromycin on Corneal Epithelial and Endothelial Apoptosis in a Rat Model of Corneal Alkali Burn. | 2016 | Cornea | pmid:26751994 |
| Zhou T et al. | Fabrication of a Selective and Sensitive Sensor Based on Molecularly Imprinted Polymer/Acetylene Black for the Determination of Azithromycin in Pharmaceuticals and Biological Samples. | 2016 | PLoS ONE | pmid:26820753 |
| Russell DW et al. | Disease phenotyping in chronic obstructive pulmonary disease: the neutrophilic endotype. | 2016 | Curr Opin Pulm Med | pmid:26717512 |
| Kadota T et al. | Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease. | 2016 | BMC Infect. Dis. | pmid:26818764 |
| Wladis EJ et al. | Oral Antibiotics for Meibomian Gland-Related Ocular Surface Disease: A Report by the American Academy of Ophthalmology. | 2016 | Ophthalmology | pmid:26707417 |
| Deshpande D et al. | Azithromycin Dose To Maximize Efficacy and Suppress Acquired Drug Resistance in Pulmonary Mycobacterium avium Disease. | 2016 | Antimicrob. Agents Chemother. | pmid:26810646 |
| Stokholm J et al. | Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial. | 2016 | Lancet Respir Med | pmid:26704020 |
| Swatton JE et al. | Impact of Azithromycin on the Quorum Sensing-Controlled Proteome of Pseudomonas aeruginosa. | 2016 | PLoS ONE | pmid:26808156 |
| Afshar M et al. | Azithromycin use and outcomes in severe sepsis patients with and without pneumonia. | 2016 | J Crit Care | pmid:26803186 |
| Lenehan PJ et al. | An evaluation strategy for potential QTc prolongation with chronic azithromycin therapy in cystic fibrosis. | 2016 | J. Cyst. Fibros. | pmid:26698953 |
| Lee H et al. | New treatment options for infections caused by increasingly antimicrobial-resistant Neisseria gonorrhoeae. | 2016 | Expert Rev Anti Infect Ther | pmid:26690658 |
| Nakajima T et al. | Microbiological and Clinical Effects of Sitafloxacin and Azithromycin in Periodontitis Patients Receiving Supportive Periodontal Therapy. | 2016 | Antimicrob. Agents Chemother. | pmid:26729495 |
| Jentsch HF et al. | Nonsurgical therapy of chronic periodontitis with adjunctive systemic azithromycin or amoxicillin/metronidazole. | 2016 | Clin Oral Investig | pmid:26685849 |
| Deguchi T et al. | Multidrug-Resistant Mycoplasma genitalium Is Increasing. | 2016 | Clin. Infect. Dis. | pmid:26494825 |
| Kong FY et al. | Reply to Deguchi et al. | 2016 | Clin. Infect. Dis. | pmid:26494824 |
| Al-Hity A and Lockington D | Oral azithromycin as the systemic treatment of choice in the treatment of meibomian gland disease. | 2016 | Clin. Experiment. Ophthalmol. | pmid:26441357 |
| Ruttens D et al. | Prophylactic Azithromycin Therapy After Lung Transplantation: Post hoc Analysis of a Randomized Controlled Trial. | 2016 | Am. J. Transplant. | pmid:26372728 |
| Wu TS et al. | Postcesarean section wound infection caused by Mycobacterium massiliense. | 2016 | J Microbiol Immunol Infect | pmid:26350122 |
| Osborne LG et al. | Enteric fever in a British soldier from Sierra Leone. | 2016 | J R Army Med Corps | pmid:26243802 |
| Li SQ et al. | Establishment of a new animal model of azithromycin-induced liver injury and study the molecular pathological change during the process. | 2016 | Hum Exp Toxicol | pmid:26205530 |
| Nappe TM et al. | Stevens-Johnson syndrome after treatment with azithromycin: an uncommon culprit. | 2016 | Am J Emerg Med | pmid:26194400 |
| Derad I et al. | Hypertension and mild chronic kidney disease persist following severe haemolytic uraemic syndrome caused by Shiga toxin-producing Escherichia coli O104:H4 in adults. | 2016 | Nephrol. Dial. Transplant. | pmid:26180049 |
| Steeples LR et al. | Real-time PCR using the 529 bp repeat element for the diagnosis of atypical ocular toxoplasmosis. | 2016 | Br J Ophthalmol | pmid:26174811 |
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| Chang CC et al. | Disseminated cat-scratch disease: case report and review of the literature. | 2016 | Paediatr Int Child Health | pmid:25940800 |
| Dey SK et al. | Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. | 2015 Jul-Aug | Indian J Pharmacol | pmid:26288467 |
| Ercan E et al. | Effects of azithromycin versus metronidazole-amoxicillin combination as an adjunct to nonsurgical periodontal therapy of generalized aggressive periodontitis. | 2015 Jul-Aug | Niger J Clin Pract | pmid:25966723 |
| Walicka-Serzysko K and Sands D | The clinical presentations of pulmonary aspergillosis in children with cystic fibrosis - preliminary report. | 2015 Jan-Mar | Dev Period Med | pmid:26003072 |
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| Unger HW et al. | Impact of intermittent preventive treatment in pregnancy with azithromycin-containing regimens on maternal nasopharyngeal carriage and antibiotic sensitivity of Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus: a cross-sectional survey at delivery. | 2015 | J. Clin. Microbiol. | pmid:25673788 |
| Waag DM | Efficacy of postexposure therapy against glanders in mice. | 2015 | Antimicrob. Agents Chemother. | pmid:25645854 |
| Stevens K et al. | Neisseria gonorrhoeae isolates with high-level resistance to azithromycin in Australia. | 2015 | J. Antimicrob. Chemother. | pmid:25480491 |
| Hocking JS et al. | Treatment of rectal chlamydia infection may be more complicated than we originally thought. | 2015 | J. Antimicrob. Chemother. | pmid:25480490 |
| Radhakrishnan SV et al. | Preventive azithromycin treatment reduces noninfectious lung injury and acute graft-versus-host disease in a murine model of allogeneic hematopoietic cell transplantation. | 2015 | Biol. Blood Marrow Transplant. | pmid:25445642 |
| Lai PC et al. | Azithromycin enhances phagocytic killing of Aggregatibacter actinomycetemcomitans Y4 by human neutrophils. | 2015 | J. Periodontol. | pmid:25186779 |
| Hare KM et al. | Nasopharyngeal carriage and macrolide resistance in Indigenous children with bronchiectasis randomized to long-term azithromycin or placebo. | 2015 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:26363637 |
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| Vandermeulen E et al. | BAL neutrophilia in azithromycin-treated lung transplant recipients: Clinical significance. | 2015 | Transpl. Immunol. | pmid:26168736 |
| Llata E et al. | Management of Pelvic Inflammatory Disease in Selected U.S. Sexually Transmitted Disease Clinics: Sexually Transmitted Disease Surveillance Network, January 2010-December 2011. | 2015 | Sex Transm Dis | pmid:26165434 |
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| Barni S et al. | Azithromycin is more allergenic than clarithromycin in children with suspected hypersensitivity reaction to macrolides. | 2015 | J Investig Allergol Clin Immunol | pmid:25997306 |
| Franco M et al. | Pulmonary mycobacterial spindle cell pseudotumor in a lung transplant patient: progression without therapy and response to therapy. | 2015 | Transpl Infect Dis | pmid:25846671 |
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