Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Tooth Mobility D014086 2 associated lipids
Toxoplasmosis, Congenital D014125 2 associated lipids
Hoarseness D006685 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Bites, Human D001734 2 associated lipids
Penile Diseases D010409 2 associated lipids
Herpes Genitalis D006558 2 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Vergis EN et al. Azithromycin vs cefuroxime plus erythromycin for empirical treatment of community-acquired pneumonia in hospitalized patients: a prospective, randomized, multicenter trial. 2000 Arch. Intern. Med. pmid:10809032
Sasaki TY and Sumida KN Angioimmunoblastic T-cell lymphoma (AIL-TCL) following macrolide administration. 2000 Hawaii Med J pmid:10800250
Kozyrskyj AL et al. Short course antibiotics for acute otitis media. 2000 Cochrane Database Syst Rev pmid:10796591
Skerk V et al. Comparative analysis of azithromycin and doxycycline efficacy in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum. 2000 J Chemother pmid:10789560
Miller SA et al. Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human vascular smooth muscle and induces cellular proliferation. 2000 J. Surg. Res. pmid:10781378
Ress BD and Gross EM Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. 2000 Ann. Otol. Rhinol. Laryngol. pmid:10778901
Bujanda L et al. Ranitidine bismuth citrate plus azithromycin for Helicobacter pylori eradication. 2000 J. Clin. Gastroenterol. pmid:10777206
Donders GG Treatment of sexually transmitted bacterial diseases in pregnant women. 2000 Drugs pmid:10776830
Laming AC et al. A targeted, single-dose azithromycin strategy for trachoma. 2000 Med. J. Aust. pmid:10772587
Najib MM et al. Cost-effectiveness of sparfloxacin compared with other oral antimicrobials in outpatient treatment of community-acquired pneumonia. 2000 Pharmacotherapy pmid:10772376
Brieland JK et al. Efficacy of SCH27899 in an animal model of Legionnaires' disease using immunocompromised A/J mice. 2000 Antimicrob. Agents Chemother. pmid:10770771
El-Sadr WM et al. Discontinuation of prophylaxis for Mycobacterium avium complex disease in HIV-infected patients who have a response to antiretroviral therapy. Terry Beirn Community Programs for Clinical Research on AIDS. 2000 N. Engl. J. Med. pmid:10766581
Somani J et al. Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure. 2000 J. Infect. Dis. pmid:10762573
Diculencu D et al. [The postantibiotic effect of azithromycin on respiratory pathogens]. 1998 Jul-Dec Rev Med Chir Soc Med Nat Iasi pmid:10756861
Wenisch C [Pharmacokinetic effects of antibiotics on the development of bacterial resistance particularly in reference to azithromycin]. 2000 Wien Med Wochenschr pmid:10756595
Nishi Y et al. [Effect of macrolide antibiotics on adhesion by cancer cells]. 2000 Jpn J Antibiot pmid:10756450
Giacometti A et al. Activity of nitazoxanide alone and in combination with azithromycin and rifabutin against Cryptosporidium parvum in cell culture. 2000 J. Antimicrob. Chemother. pmid:10747821
Schissel DJ et al. Azithromycin eruption in infectious mononucleosis: a proposed mechanism of interaction. 2000 Cutis pmid:10738636
Ouchi K Chlamydia pneumoniae and atherosclerosis. 1999 Jpn. J. Infect. Dis. pmid:10738358
Potts JM et al. Association of chronic urinary symptoms in women and Ureaplasma urealyticum. 2000 Urology pmid:10736488