Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Amebiasis D000562 2 associated lipids
Pericoronitis D010497 2 associated lipids
Lung Diseases, Parasitic D008174 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Tuberculosis, Urogenital D014401 2 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Toxoplasmosis, Ocular D014126 2 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Authors Title Published Journal PubMed Link
Brihmer C et al. Efficacy and safety of azithromycin versus lymecyline in the treatment of genital chlamydial infections in women. 1996 Scand. J. Infect. Dis. pmid:8953672
Van Bambeke F et al. Interaction of the macrolide azithromycin with phospholipids. I. Inhibition of lysosomal phospholipase A1 activity. 1996 Eur. J. Pharmacol. pmid:8957238
Montenez JP et al. Interaction of the macrolide azithromycin with phospholipids. II. Biophysical and computer-aided conformational studies. 1996 Eur. J. Pharmacol. pmid:8957239
Prescott LM Macrolides, azalides, and streptogrammins. 1996 J Int Assoc Physicians AIDS Care pmid:11363516
Currier J Progress report: prophylaxis and therapy for MAC. 1996 AIDS Clin Care pmid:11363599
Kuzman I et al. Azithromycin in the treatment of pneumonias caused by Chlamydia spp: a retrospective study. 1996 Int J Clin Pharmacol Res pmid:9172008
Old drug approved for MAC prevention. 1996 AIDS Alert pmid:11363659
Torres G MAC prophylaxis revisited. 1996 GMHC Treat Issues pmid:11363706
Antivirals key to MAC prevention regimen. 1996 AIDS Alert pmid:11363722
Marco M Opportunistic infections in Vancouver. 1996 GMHC Treat Issues pmid:11363841
Azithromycin effective in preventing MAC. 1996 AIDS Alert pmid:11363857
Wittner M et al. Atovaquone in the treatment of Babesia microti infections in hamsters. 1996 Am. J. Trop. Med. Hyg. pmid:8780464
Apseloff G et al. Severe neutropenia caused by recommended prophylactic doses of rifabutin. 1996 Lancet pmid:8782773
ZaÄ­tseva EA et al. [Comparative study of the antimicrobial activity of pefloxacin, ciprofloxacin, norfloxacin and azithromycin with respect to Strains of Yersinia pseudotuberculosis]. 1996 Antibiot. Khimioter. pmid:8762820
Lode H et al. Azithromycin--review of key chemical, pharmacokinetic and microbiological features. 1996 J. Antimicrob. Chemother. pmid:8818841
Girard AE et al. Correlation of increased azithromycin concentrations with phagocyte infiltration into sites of localized infection. 1996 J. Antimicrob. Chemother. pmid:8818842
Boran M et al. Improvement in cyclosporine A associated gingival hyperplasia with azithromycin therapy. 1996 Transplant. Proc. pmid:8769234
Luft BJ et al. Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial. 1996 Ann. Intern. Med. pmid:8610947
Ridgway GL Azithromycin in sexually transmitted diseases. 1996 Int J STD AIDS pmid:8652719
Young LS Azithromycin in the management of opportunistic infections. 1996 Int J STD AIDS pmid:8652721
Chang HR The potential role of azithromycin in the treatment of prophylaxis of toxoplasmosis. 1996 Int J STD AIDS pmid:8652722
Waugh MA Azithromycin in gonorrhoea. 1996 Int J STD AIDS pmid:8652723
Young LS Treatment and prophylaxis of Mycobacterium avium complex. 1996 Int J STD AIDS pmid:8652724
Furukawa S and Okada T [A clinical evaluation of azithromycin in the treatment of pediatric infection]. 1996 Jpn J Antibiot pmid:8988413
Okada T et al. [Pharmacokinetic and clinical evaluations of azithromycin in the pediatric field]. 1996 Jpn J Antibiot pmid:8988414
Ishida Y et al. [Pharmacokinetic and clinical evaluation of azithromycin in pediatric infections]. 1996 Jpn J Antibiot pmid:8988415
Ohtsuka Y et al. [Pharmacokinetic and clinical studies on azithromycin in children]. 1996 Jpn J Antibiot pmid:8988416
Cammarota G et al. Helicobacter pylori eradication using one-week low-dose lansoprazole plus amoxycillin and either clarithromycin or azithromycin. 1996 Aliment. Pharmacol. Ther. pmid:8971300
Pilotto A et al. Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers. 1996 Aliment. Pharmacol. Ther. pmid:8971305
Andenaes K et al. Preoperative bacterial colonization and its influence on postoperative wound infections in plastic surgery. 1996 J. Hosp. Infect. pmid:8971618
Pozniak A and Nelson MR Against the proposition: all patients with advanced HIV disease should be offered rifabutin prophylaxis. 1996 Genitourin Med pmid:8976832
Schwartz RA et al. Bacillary angiomatosis in an HIV seronegative patient on systemic steroid therapy. 1996 Br. J. Dermatol. pmid:8977724
Chulig I [Pharmacokinetic profile of azithromycin. Role in the treatment of genital Chlamydia infections]. 1996 Antibiot. Khimioter. pmid:8929112
Kuznetsova SM ["Sumamed in the treatment of urogenital infections"]. 1996 Antibiot. Khimioter. pmid:8929115
Skripkin IuK et al. [The problem of diagnosis and treatment of urogenital chlamydiosis in Russia]. 1996 Antibiot. Khimioter. pmid:8929120
Vasil'ev MM and Gazarian IIu [Clinico-laboratory evaluation of the effectiveness of azithromycin in the treatment of patients with Chlamydia and mixed Chlamydia-gonorrhea infections]. 1996 Antibiot. Khimioter. pmid:8929122
Schaad UB and Heynen G Evaluation of the efficacy, safety and toleration of azithromycin vs. penicillin V in the treatment of acute streptococcal pharyngitis in children: results of a multicenter, open comparative study. The Swiss Tonsillopharyngitis Study Group. 1996 Pediatr. Infect. Dis. J. pmid:8878223
McLinn S and Williams D Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. 1996 Pediatr. Infect. Dis. J. pmid:8878239
McCarty J A multicenter, open label trial of azithromycin for the treatment of children with acute otitis media. 1996 Pediatr. Infect. Dis. J. pmid:8878240
Bauernfeind A et al. Comparative pharmacodynamics of clarithromycin and azithromycin against respiratory pathogens. 1995 Sep-Oct Infection pmid:8557398
Erdogru T et al. The treatment of non-gonococcal urethritis with single dose oral azithromycin. 1995 Sep-Oct J. Int. Med. Res. pmid:8529783
Haddix AC et al. The cost effectiveness of azithromycin for Chlamydia trachomatis infections in women. 1995 Sep-Oct Sex Transm Dis pmid:7502180
Sternon J et al. Azithromycin compared with clarithromycin in the treatment of adult patients with acute purulent tracheobronchitis: a cost of illness study. 1995 Nov-Dec J. Int. Med. Res. pmid:8746608
Höffler D et al. Pharmacokinetics of azithromycin in normal and impaired renal function. 1995 Nov-Dec Infection pmid:8655206
Hashisaki GT Update on macrolide antibiotics. 1995 May-Jun Am J Otolaryngol pmid:7661309
What's in the water? 1995 Mar-Apr Treat Rev pmid:11362299
Rifabutin for MAC questioned. 1995 Jul-Aug Posit Aware pmid:11362571
Amin NM and Breadon G An open-label, noncomparative study to evaluate the efficacy, safety, and tolerability of azithromycin in the treatment of patients with acute sinusitis. 1995 Jul-Aug Clin Ther pmid:8565033
Qadri SM et al. Antibacterial activity of azithromycin against Brucella melitensis. 1995 Jul-Aug Chemotherapy pmid:7555205
Nuovo J et al. Cost-effectiveness analysis of five different antibiotic regimens for the treatment of uncomplicated Chlamydia trachomatis cervicitis. 1995 Jan-Feb J Am Board Fam Pract pmid:7701965