| MeSH term | MeSH ID | Detail |
|---|---|---|
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Pseudomonas Infections | D011552 | 25 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Malaria, Falciparum | D016778 | 22 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Eisenberg E and Barza M | Azithromycin and clarithromycin. | 1994 | Curr Clin Top Infect Dis | pmid:8086122 |
| Lang R et al. | Therapeutic effects of roxithromycin and azithromycin in experimental murine brucellosis. | 1994 Jul-Aug | Chemotherapy | pmid:8082413 |
| Uzun O et al. | Efficacy of a three-day course of azithromycin in the treatment of community-acquired pneumococcal pneumonia. Preliminary report. | 1994 | J Chemother | pmid:8071680 |
| Bermudez LE et al. | Rifabutin and sparfloxacin but not azithromycin inhibit binding of Mycobacterium avium complex to HT-29 intestinal mucosal cells. | 1994 | Antimicrob. Agents Chemother. | pmid:8067766 |
| Lopatkin NA et al. | [Use of azithromycin ("Sumamded") in the treatment of infectious-inflammatory diseases of the lower urinary tract and male genitalia]. | 1993 | Antibiot. Khimioter. | pmid:8060189 |
| Sidorenko SV | [Azithromycin--an antibiotic of the azalide group]. | 1993 | Antibiot. Khimioter. | pmid:8060181 |
| Gomberg MA and MashkilleÄson AL | [Use of azithromycin in long existing urogenital chlamydia infections and its association with primary syphilis]. | 1993 | Antibiot. Khimioter. | pmid:8060178 |
| Rehg J | New potential therapies for cryptosporidiosis: an analysis of variables affecting drug efficacy. | 1994 | Folia Parasitol. | pmid:8050751 |
| Katelaris PH et al. | Activity of metronidazole, azithromycin and three benzimidazoles on Giardia lamblia growth and attachment to a human intestinal cell line. | 1994 | Aliment. Pharmacol. Ther. | pmid:8038350 |
| Trevisi P et al. | Toxic pustuloderma associated with azithromycin. | 1994 | Clin. Exp. Dermatol. | pmid:8033402 |
| Wolinsky E | Mycobacterium avium strains resistant to clarithromycin and azithromycin. | 1994 | Antimicrob. Agents Chemother. | pmid:8031406 |
| Heifets L et al. | Mycobacterium avium strains resistant to clarithromycin and azithromycin. | 1993 | Antimicrob. Agents Chemother. | pmid:8031351 |
| Ishida K et al. | In vitro and in vivo activities of macrolides against Mycoplasma pneumoniae. | 1994 | Antimicrob. Agents Chemother. | pmid:8031048 |
| Dorrell L et al. | Intravenous azithromycin as salvage therapy in a patient with Legionnaire's disease. | 1994 | Thorax | pmid:8016806 |
| Steven N et al. | Corticosteroid therapy for AIDS patients with Mycobacterium avium-intracellulare infection. | 1994 | AIDS | pmid:8011231 |
| Bush MR and Rosa C | Azithromycin and erythromycin in the treatment of cervical chlamydial infection during pregnancy. | 1994 | Obstet Gynecol | pmid:8008325 |
| Cazzola M et al. | Evaluation of lung tissue and hilar lymph node concentrations of azithromycin. | 1994 | Int J Clin Pharmacol Ther | pmid:8004364 |
| Pacor ML et al. | [Safety of azithromycin in patients allergic to penicillin and cephalosporin]. | 1994 | Clin Ter | pmid:8001336 |
| Andersen SL et al. | Efficacy of azithromycin as a causal prophylactic agent against murine malaria. | 1994 | Antimicrob. Agents Chemother. | pmid:7986022 |
| Klemens SP and Cynamon MH | Intermittent azithromycin for treatment of Mycobacterium avium infection in beige mice. | 1994 | Antimicrob. Agents Chemother. | pmid:7986001 |
| [Azithromycin--an innovative macrolide antibiotic for 3-day-therapy]. | 1994 | Immun. Infekt. | pmid:7982710 | |
| Schwab JC et al. | Localization of azithromycin in Toxoplasma gondii-infected cells. | 1994 | Antimicrob. Agents Chemother. | pmid:7979295 |
| Klemens SP and Cynamon MH | Activities of azithromycin and clarithromycin against nontuberculous mycobacteria in beige mice. | 1994 | Antimicrob. Agents Chemother. | pmid:7979271 |
| Cynamon MH et al. | Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice. | 1994 | Antimicrob. Agents Chemother. | pmid:7979270 |
| [Newly approved specialty drugs in Austria and new knowledge about currently available specialty drugs. Zithromax capsules, dried syrup]. | 1994 | Wien. Klin. Wochenschr. | pmid:7975673 | |
| Tyndall MW et al. | Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. | 1994 Jul-Aug | Sex Transm Dis | pmid:7974076 |
| Dumas JL et al. | Evaluation of the efficacy of prolonged administration of azithromycin in a murine model of chronic toxoplasmosis. | 1994 | J. Antimicrob. Chemother. | pmid:7961197 |
| Sifrim D et al. | Comparison of the effects of midecamycin acetate and azithromycin on gastrointestinal motility in man. | 1994 | Drugs Exp Clin Res | pmid:7956719 |
| Bottaro G et al. | [Evaluation of the clinical efficacy of azithromycin in acute respiratory infections in children]. | 1994 | Clin Ter | pmid:7955949 |
| Wildfeuer A et al. | Distribution of orally administered azithromycin in various blood compartments. | 1994 | Int J Clin Pharmacol Ther | pmid:7952797 |
| Rehg JE | A comparison of anticryptosporidial activity of paromomycin with that of other aminoglycosides and azithromycin in immunosuppressed rats. | 1994 | J. Infect. Dis. | pmid:7930738 |
| Hughes WT et al. | Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model. | 1994 | J. Infect. Dis. | pmid:7930735 |
| Klepser ME et al. | Treatment of uncomplicated infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae. | 1994 | Conn Med | pmid:7924316 |
| Jones RN et al. | Validation of NCCLS macrolide (azithromycin, clarithromycin, and erythromycin) interpretive criteria for Haemophilus influenzae tested with the Haemophilus test medium. National Committee for Clinical Laboratory Standards. | 1994 | Diagn. Microbiol. Infect. Dis. | pmid:7924221 |
| Wallace MR et al. | Azithromycin and typhoid. | 1994 | Lancet | pmid:7911192 |
| Kuschner RA et al. | Azithromycin prophylaxis against a chloroquine-resistant strain of Plasmodium falciparum. | 1994 | Lancet | pmid:7910886 |
| Wallace MR et al. | Ototoxicity with azithromycin. | 1994 | Lancet | pmid:7904701 |
| Donowitz GR | Tissue-directed antibiotics and intracellular parasites: complex interaction of phagocytes, pathogens, and drugs. | 1994 | Clin. Infect. Dis. | pmid:7893881 |
| Andersen SL et al. | Activity of azithromycin as a blood schizonticide against rodent and human plasmodia in vivo. | 1995 | Am. J. Trop. Med. Hyg. | pmid:7872444 |
| al-Assi MT et al. | Azithromycin triple therapy for Helicobacter pylori infection: azithromycin, tetracycline, and bismuth. | 1995 | Am. J. Gastroenterol. | pmid:7872278 |
| Wang JH et al. | Azithromycin in the treatment of pneumonia caused by Chlamydia pneumoniae: report of a case. | 1994 | J. Formos. Med. Assoc. | pmid:7866068 |
| Wahlstrom E et al. | Improvement in cyclosporine-associated gingival hyperplasia with azithromycin therapy. | 1995 | N. Engl. J. Med. | pmid:7854392 |
| Rapp RP et al. | New macrolide antibiotics: usefulness in infections caused by mycobacteria other than Mycobacterium tuberculosis. | 1994 | Ann Pharmacother | pmid:7849341 |
| Freeman CD et al. | Intracellular and extracellular penetration of azithromycin into inflammatory and noninflammatory blister fluid. | 1994 | Antimicrob. Agents Chemother. | pmid:7840585 |
| Niki Y et al. | In vitro and in vivo activities of azithromycin, a new azalide antibiotic, against chlamydia. | 1994 | Antimicrob. Agents Chemother. | pmid:7840560 |
| Dessau RB | [Azithromycin]. | 1995 | Ugeskr. Laeg. | pmid:7831733 |
| Friis HM | [Azithromycin--an exciting new antibiotic]. | 1995 | Ugeskr. Laeg. | pmid:7831724 |
| Chiarini F et al. | Chlamydia trachomatis genitourinary infections: laboratory diagnosis and therapeutic aspects. Evaluation of in vitro and in vivo effectiveness of azithromycin. | 1994 | J Chemother | pmid:7830100 |
| Beckers CJ et al. | Inhibition of cytoplasmic and organellar protein synthesis in Toxoplasma gondii. Implications for the target of macrolide antibiotics. | 1995 | J. Clin. Invest. | pmid:7814637 |
| Raszka WV et al. | Multifocal M. intracellulare osteomyelitis in an immunocompetent child. | 1994 | Clin Pediatr (Phila) | pmid:7813141 |