Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Cardiovascular Diseases D002318 24 associated lipids
Cat Diseases D002371 12 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Uterine Cervicitis D002575 3 associated lipids
Chancroid D002602 4 associated lipids
Chlamydia Infections D002690 7 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Chronic Disease D002908 7 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Colitis D003092 69 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Misra R and Prasad KN Antimicrobial susceptibility to azithromycin among Salmonella enterica Typhi and Paratyphi A isolates from India. 2016 J. Med. Microbiol. pmid:27902389
Wang A et al. Effects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia. 2016 Sci Rep pmid:27405358
Menzel M et al. Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients. 2016 Sci Rep pmid:27350308
Wind CM et al. Time to clearance of Chlamydia trachomatis RNA and DNA after treatment in patients coinfected with Neisseria gonorrhoeae - a prospective cohort study. 2016 BMC Infect. Dis. pmid:27724878
Yasuda M et al. Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility of azithromycin and increase in the failure of azithromycin therapy in male gonococcal urethritis in Sendai in 2015. 2016 J. Infect. Chemother. pmid:27578029
Tita AT et al. Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. 2016 N. Engl. J. Med. pmid:27682034
Committee Opinion No. 645: Dual Therapy for Gonococcal Infections. 2016 Obstet Gynecol pmid:27548425
Waites KB et al. In Vitro Activities of Omadacycline (PTK 0796) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas. 2016 Antimicrob. Agents Chemother. pmid:27671057
Committee Opinion No. 645 Summary: Dual Therapy for Gonococcal Infections. 2016 Obstet Gynecol pmid:27548417
Li S et al. Two case reports: Whole genome sequencing of two clinical macrolide-resistant Mycoplasma pneumoniae isolates with different responses to azithromycin. 2016 Medicine (Baltimore) pmid:27661056
Mustapha NA et al. Impact of different antibiotics on methane production using waste-activated sludge: mechanisms and microbial community dynamics. 2016 Appl. Microbiol. Biotechnol. pmid:27531514
Brunner A et al. Emerging azithromycin-resistance among the Neisseria gonorrhoeae strains isolated in Hungary. 2016 Ann. Clin. Microbiol. Antimicrob. pmid:27646968
Schachter J Azithromycin versus Doxycycline for Chlamydia. 2016 N. Engl. J. Med. pmid:27144857
Zhou QT et al. How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder? 2016 AAPS J pmid:27255350
MUW researcher of the month Franz Ratzinger. 2016 Wien. Klin. Wochenschr. pmid:27113348
Yuan ZF et al. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with Mycoplasma pneumoniae infection. 2016 BMC Infect. Dis. pmid:27230114
Kloepfer KM Azithromycin may prevent severe respiratory-infection-induced wheezing. 2016 J. Pediatr. pmid:27112084
Economopoulos KP et al. Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase. 2016 Diabetes Obes Metab pmid:26876427
Sridhar S et al. High recurrence rate supports need for secondary prophylaxis in non-HIV patients with disseminated mycobacterium avium complex infection: a multi-center observational study. 2016 BMC Infect. Dis. pmid:26861696
Peters RP et al. Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome. 2016 Sex Transm Dis pmid:26760182
Hodgson D et al. The Effects of Azithromycin in Treatment-Resistant Cough: A Randomized, Double-Blind, Placebo-Controlled Trial. 2016 Chest pmid:26836927
Zheng Z et al. Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. 2016 J. Antibiot. pmid:27118243
Gratrix J et al. A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men. 2016 Sex Transm Dis pmid:26760180
Kumaraswamy M et al. Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia. 2016 J. Antimicrob. Chemother. pmid:26832758
Arikan S et al. Effect of Topically Applied Azithromycin on Corneal Epithelial and Endothelial Apoptosis in a Rat Model of Corneal Alkali Burn. 2016 Cornea pmid:26751994
Zhou T et al. Fabrication of a Selective and Sensitive Sensor Based on Molecularly Imprinted Polymer/Acetylene Black for the Determination of Azithromycin in Pharmaceuticals and Biological Samples. 2016 PLoS ONE pmid:26820753
Russell DW et al. Disease phenotyping in chronic obstructive pulmonary disease: the neutrophilic endotype. 2016 Curr Opin Pulm Med pmid:26717512
Deguchi T et al. Multidrug-Resistant Mycoplasma genitalium Is Increasing. 2016 Clin. Infect. Dis. pmid:26494825
Kong FY et al. Reply to Deguchi et al. 2016 Clin. Infect. Dis. pmid:26494824
Chang CC et al. Disseminated cat-scratch disease: case report and review of the literature. 2016 Paediatr Int Child Health pmid:25940800
Dey SK et al. Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. 2015 Jul-Aug Indian J Pharmacol pmid:26288467
Ercan E et al. Effects of azithromycin versus metronidazole-amoxicillin combination as an adjunct to nonsurgical periodontal therapy of generalized aggressive periodontitis. 2015 Jul-Aug Niger J Clin Pract pmid:25966723
Walicka-Serzysko K and Sands D The clinical presentations of pulmonary aspergillosis in children with cystic fibrosis - preliminary report. 2015 Jan-Mar Dev Period Med pmid:26003072
Pandhi D et al. Author's Response--The efficacy of azithromycin in pityriasis rosea: a randomized, double-blind, placebo-controlled trial. 2015 Jan-Feb Indian J Dermatol Venereol Leprol pmid:25566901
Drago F et al. The efficacy of macrolides and acyclovir in pityriasis rosea. 2015 Jan-Feb Indian J Dermatol Venereol Leprol pmid:25566900
Martin DL et al. Serology for trachoma surveillance after cessation of mass drug administration. 2015 PLoS Negl Trop Dis pmid:25714363
Euba B et al. Relationship between azithromycin susceptibility and administration efficacy for nontypeable Haemophilus influenzae respiratory infection. 2015 Antimicrob. Agents Chemother. pmid:25712355
Steffen R et al. Traveler's diarrhea: a clinical review. 2015 JAMA pmid:25562268
Kapil R et al. Investigating the epidemiology of repeat Chlamydia trachomatis detection after treatment by using C. trachomatis OmpA genotyping. 2015 J. Clin. Microbiol. pmid:25472488
Gardiner SJ et al. Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. 2015 Cochrane Database Syst Rev pmid:25566754
Doyle CJ et al. Azithromycin suppresses P. gingivalis LPS-induced pro-inflammatory cytokine and chemokine production by human gingival fibroblasts in vitro. 2015 Clin Oral Investig pmid:24806810
Young TP Banana fibers masquerading as worms in the stool of a 14-month-old girl. 2015 Clin Pediatr (Phila) pmid:24803631
Siekmeier R et al. Inhalation of macrolides: a novel approach to treatment of pulmonary infections. 2015 Adv. Exp. Med. Biol. pmid:25252902
Kalonji LM et al. Invasive Salmonella Infections at Multiple Surveillance Sites in the Democratic Republic of the Congo, 2011-2014. 2015 Clin. Infect. Dis. pmid:26449951
Marks M et al. Challenges and key research questions for yaws eradication. 2015 Lancet Infect Dis pmid:26362174
Fifer H et al. Gonorrhoea treatment position statement. 2015 Sex Transm Infect pmid:26195472
Bowen A et al. Notes from the Field: Outbreaks of Shigella sonnei Infection with Decreased Susceptibility to Azithromycin Among Men Who Have Sex with Men - Chicago and Metropolitan Minneapolis-St. Paul, 2014. 2015 MMWR Morb. Mortal. Wkly. Rep. pmid:26042652
Lu H et al. High frequency of the 23S rRNA A2058G mutation of Treponema pallidum in Shanghai is associated with a current strategy for the treatment of syphilis. 2015 Emerg Microbes Infect pmid:26038763
Rice LB Will use of combination cephalosporin/azithromycin therapy forestall resistance to cephalosporins in Neisseria gonorrhoeae? 2015 Sex Transm Infect pmid:25926405
Lynagh Y et al. Detailed characterization of the first high-level azithromycin-resistant Neisseria gonorrhoeae cases in Ireland. 2015 J. Antimicrob. Chemother. pmid:25907073