Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Cardiovascular Diseases D002318 24 associated lipids
Cat Diseases D002371 12 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Uterine Cervicitis D002575 3 associated lipids
Chancroid D002602 4 associated lipids
Chlamydia Infections D002690 7 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Chronic Disease D002908 7 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Colitis D003092 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Sanchez Garcia D et al. Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) - A comparison with lysosomotropic drugs. 2018 Chem. Biol. Interact. pmid:29248446
Afghani T et al. Preventing Long-Term Ocular Complications of Trachoma With Topical Azithromycin: A 3-Year Follow-up Study. 2017 Jan-Feb Asia Pac J Ophthalmol (Phila) pmid:28161923
Horner PJ and Martin DH Mycoplasma genitalium Infection in Men. 2017 J. Infect. Dis. pmid:28838074
Bradshaw CS et al. New Horizons in Mycoplasma genitalium Treatment. 2017 J. Infect. Dis. pmid:28838073
Gaydos CA Mycoplasma genitalium: Accurate Diagnosis Is Necessary for Adequate Treatment. 2017 J. Infect. Dis. pmid:28838072
Ribeiro M et al. Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells. 2017 Exp. Parasitol. pmid:28803905
Benn K et al. Bradycardia and Hypothermia Complicating Azithromycin Treatment. 2017 Am J Case Rep pmid:28798290
Bergeron A et al. Effect of Azithromycin on Airflow Decline-Free Survival After Allogeneic Hematopoietic Stem Cell Transplant: The ALLOZITHRO Randomized Clinical Trial. 2017 JAMA pmid:28787506
Dolezelova E et al. Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats. 2017 World J. Gastroenterol. pmid:29209109
Wang CM et al. Synthesis and Antibacterial Evaluation of a Series of 11,12-Cyclic Carbonate Azithromycin-3-O-descladinosyl-3-O-carbamoyl Glycosyl Derivatives. 2017 Molecules pmid:29207567
Rasmussen LD et al. Follicular bronchiolitis in an HIV-infected individual on combination antiretroviral therapy with low CD4+ cell count but sustained viral suppression. 2017 BMJ Case Rep pmid:29191821
Wiesenfeld HC Screening for Chlamydia trachomatis Infections in Women. 2017 N. Engl. J. Med. pmid:28225683
Shmarina G et al. Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression. 2017 Int. Arch. Allergy Immunol. pmid:28219060
Ramappa M et al. Successful Medical Management of Presumptive Pythium insidiosum Keratitis. 2017 Cornea pmid:28207431
González-Beiras C et al. Yaws Osteoperiostitis Treated with Single-Dose Azithromycin. 2017 Am. J. Trop. Med. Hyg. pmid:28193743
Ivanová L et al. Estimation of amount of selected pharmaceuticals sorbed onto digested sludge from wastewater treatment plant Bratislava-Petržalka. 2017 Environ. Res. pmid:28183039
Thakur SD et al. Resistance to Ceftriaxone and Azithromycin in Neisseria gonorrhoeae Isolates From 7 Countries of South America and the Caribbean: 2010-2011. 2017 Sex Transm Dis pmid:28178114
Boggess KA et al. Risk Factors for Postcesarean Maternal Infection in a Trial of Extended-Spectrum Antibiotic Prophylaxis. 2017 Obstet Gynecol pmid:28178058
Campanón-Toro MV et al. Acute generalized exanthematous pustulosis (AGEP) induced by azithromycin. 2017 Contact Derm. pmid:28497632
Shastay A The Absence of a Drug-Disease Interaction Alert Leads to a Child's Death. 2017 Home Healthc Now pmid:28471797
Lahra MM and Enriquez RP Australian Gonococcal Surveillance Programme, 1 July to 30 September 2016
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White AC Treatment of Early Syphilis in HIV: What Do We Really Know? 2017 Clin. Infect. Dis. pmid:28362951
Papp JR et al. Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA. 2017 Emerging Infect. Dis. pmid:28418303
Liu Y et al. Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. 2017 Life Sci. pmid:27916734
Vandooren J et al. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. 2017 PLoS ONE pmid:28369077
Valdés SO et al. Cardiac Arrest in Pediatric Patients Receiving Azithromycin. 2017 J. Pediatr. pmid:27912925
Bojang E et al. Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control. 2017 BMC Microbiol. pmid:28351345
Kong FY et al. Pharmacokinetics of a single 1g dose of azithromycin in rectal tissue in men. 2017 PLoS ONE pmid:28350806
Bornstein M et al. Factors Associated With Primary Care Physician Knowledge of the Recommended Regimen for Treating Gonorrhea. 2017 Sex Transm Dis pmid:27898574
Checa R et al. Efficacy, safety and tolerance of imidocarb dipropionate versus atovaquone or buparvaquone plus azithromycin used to treat sick dogs naturally infected with the Babesia microti-like piroplasm. 2017 Parasit Vectors pmid:28292316
Ishiguro N et al. Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients. 2017 PLoS ONE pmid:28288170
Babić I et al. Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion. 2017 Eur Arch Otorhinolaryngol pmid:27873023
Murphy TK et al. A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder. 2017 J Child Adolesc Psychopharmacol pmid:28358599
Eyre DW et al. WGS to predict antibiotic MICs for Neisseria gonorrhoeae. 2017 J. Antimicrob. Chemother. pmid:28333355
Shan LS et al. Effects of methylprednisolone or immunoglobulin when added to standard treatment with intravenous azithromycin for refractory Mycoplasma pneumoniae pneumonia in children. 2017 World J Pediatr pmid:28130749
Daimee UA et al. A 77-year-old man with fever and night sweats. 2017 Eur. J. Intern. Med. pmid:27765389
Purssell A et al. Azithromycin and Doxycycline Attenuation of Acanthamoeba Virulence in a Human Corneal Tissue Model. 2017 J. Infect. Dis. pmid:27578848
Romero L et al. Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. 2017 Cochrane Database Syst Rev pmid:29226307
Lusk MJ et al. Cervicitis: a prospective observational study of empiric azithromycin treatment in women with cervicitis and non-specific cervicitis. 2017 Int J STD AIDS pmid:26792283
Massip C et al. Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump. 2017 J. Antimicrob. Chemother. pmid:28137939
Marks M and Mabey D Single-dose azithromycin to treat latent yaws. 2017 Lancet Glob Health pmid:29107622
Mitjà O et al. Effectiveness of single-dose azithromycin to treat latent yaws: a longitudinal comparative cohort study. 2017 Lancet Glob Health pmid:29107621
Terkelsen D et al. Multidrug-resistant infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. 2017 Euro Surveill. pmid:29067905
Srivastava S et al. A 'shock and awe' thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium-intracellulare complex disease. 2017 J. Antimicrob. Chemother. pmid:28922810
Halhal B et al. Pertussis Outbreak Among Soldiers During Basic Training: The Need for Updated Protocols. 2017 Mil Med pmid:28291499
Çelik Payçu DG and Büyükbaba Boral Ö [Effects of azithromycin and Chlorella vulgaris treatment on certain cytokine values and NK cell activity in an acute murine toxoplasmosis model]. 2017 Mikrobiyol Bul pmid:28283010
Garcia-Vidal C et al. Levofloxacin versus azithromycin for treating legionella pneumonia: a propensity score analysis. 2017 Clin. Microbiol. Infect. pmid:28267637
Salman S et al. Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling. 2017 Antimicrob. Agents Chemother. pmid:28242669
Mathew A et al. Antimicrobial and Immunomodulatory Surface-Functionalized Electrospun Membranes for Bone Regeneration. 2017 Adv Healthc Mater pmid:28240815
Teng F et al. In vitro characterization of pH-sensitive azithromycin-loaded methoxy poly (ethylene glycol)-block-poly (aspartic acid-graft-imidazole) micelles. 2017 J Colloid Interface Sci pmid:28209540