Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Cardiovascular Diseases D002318 24 associated lipids
Cat Diseases D002371 12 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Uterine Cervicitis D002575 3 associated lipids
Chancroid D002602 4 associated lipids
Chlamydia Infections D002690 7 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Chronic Disease D002908 7 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Colitis D003092 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Horner P et al. Which azithromycin regimen should be used for treating ? A meta-analysis. 2018 Sex Transm Infect pmid:28717050
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Nieuwenhuis RF et al. Unusual presentation of early lymphogranuloma venereum in an HIV-1 infected patient: effective treatment with 1 g azithromycin. 2003 Sex Transm Infect pmid:14663119
Niccolai LM et al. Behavioural sources of repeat Chlamydia trachomatis infections: importance of different sex partners. 2011 Sex Transm Infect pmid:21212380
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Khosropour CM et al. Efficacy of standard therapies against Ureaplasma species and persistence among men with non-gonococcal urethritis enrolled in a randomised controlled trial. 2015 Sex Transm Infect pmid:25616607
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Falk L et al. Tetracycline treatment does not eradicate Mycoplasma genitalium. 2003 Sex Transm Infect pmid:12902584
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Pasternack R et al. Follow up of treatment: an integral part of the control of Chlamydia trachomatis infections. 1999 Sex Transm Infect pmid:10448353
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Björnelius E et al. macrolide resistance in Stockholm, Sweden. 2017 Sex Transm Infect pmid:27502694
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Marks M et al. Mass drug administration of azithromycin for trachoma reduces the prevalence of genital Chlamydia trachomatis infection in the Solomon Islands. 2016 Sex Transm Infect pmid:26888658
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Jang D et al. Correlation between culture testing of swabs and ligase chain reaction of first void urine from patients recently treated for Chlamydia trachomatis. 2003 Sex Transm Infect pmid:12794211
Gayet-Ageron A et al. Assessment of a real-time PCR test to diagnose syphilis from diverse biological samples. 2009 Sex Transm Infect pmid:19155240
Ito S et al. Selection of Mycoplasma genitalium strains harbouring macrolide resistance-associated 23S rRNA mutations by treatment with a single 1 g dose of azithromycin. 2011 Sex Transm Infect pmid:21653933
Thakur SD et al. Molecular epidemiology of Neisseria gonorrhoeae isolates from Saskatchewan, Canada: utility of NG-MAST in predicting antimicrobial susceptibility regionally. 2014 Sex Transm Infect pmid:24503900
Fifer H et al. Gonorrhoea treatment position statement. 2015 Sex Transm Infect pmid:26195472
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Carter N and Horner P Treatment regimens in non-gonococcal urethritis. 2015 Sex Transm Infect pmid:25990780
Rice LB Will use of combination cephalosporin/azithromycin therapy forestall resistance to cephalosporins in Neisseria gonorrhoeae? 2015 Sex Transm Infect pmid:25926405
Bala M et al. Trends of resistance to antimicrobials recommended currently and in the past for management of gonorrhea in the Apex STD center in India and comparison of antimicrobial resistance profile between 2002-2006 and 2007-2012. 2015 Sex Transm Dis pmid:25763675
Mabey D Azithromycin resistance in Treponema pallidum. 2009 Sex Transm Dis pmid:19801961
Martin DH The US Chlamydia trachomatis control program: successes, shortcomings and ideas for the future. 2012 Sex Transm Dis pmid:23169170
Zhou P et al. Occurrence of congenital syphilis after maternal treatment with azithromycin during pregnancy. 2007 Sex Transm Dis pmid:17589329
Handsfield HH et al. Multicenter trial of single-dose azithromycin vs. ceftriaxone in the treatment of uncomplicated gonorrhea. Azithromycin Gonorrhea Study Group. 1994 Mar-Apr Sex Transm Dis pmid:9071422
Yasin RM et al. Comparison of E-test with agar dilution methods in testing susceptibility of N. gonorrhoeae to azithromycin. 1997 Sex Transm Dis pmid:9153733
Okah E et al. Sentinel Surveillance for Expedited Partner Therapy Prescriptions Using Pharmacy Data, in 2 New York City Neighborhoods, 2015. 2017 Sex Transm Dis pmid:28079746
Howell MR et al. Control of Chlamydia trachomatis infections in female army recruits: cost-effective screening and treatment in training cohorts to prevent pelvic inflammatory disease. 1999 Sex Transm Dis pmid:10534206
Chen S et al. Universal screening or prophylactic treatment for Chlamydia trachomatis infection among women seeking induced abortions: which strategy is more cost-effective? 2007 Sex Transm Dis pmid:17414068
Zhu BY et al. Surveillance of antimicrobial susceptibilities of Neisseria gonorrhoeae in Nanning, China, 2000 to 2012. 2014 Sex Transm Dis pmid:25013979
Labbé AC et al. Periodical antibiotic treatment for the control of gonococcal and chlamydial infections among sex workers in Benin and Ghana: a cluster-randomized placebo-controlled trial. 2012 Sex Transm Dis pmid:22421690
Lechtenberg RJ et al. Variation in adherence to the treatment guidelines for Neisseria gonorrhoeae by clinical practice setting, California, 2009 to 2011. 2014 Sex Transm Dis pmid:24722391
Chaudhary C et al. A pilot study on antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Nepal. 2005 Sex Transm Dis pmid:16205307
Carlin EM and Barton SE Azithromycin as a cost-effective treatment for nongonococcal urethritis in men. 1997 Sex Transm Dis pmid:9018784
Manhart LE Has the time come to systematically test for Mycoplasma genitalium? 2009 Sex Transm Dis pmid:19734818
Steen R et al. Evidence of declining STD prevalence in a South African mining community following a core-group intervention. 2000 Sex Transm Dis pmid:10654860
Dan M et al. Pharyngeal Gonorrhea in female sex workers: Response to a single 2-g dose of azithromycin. 2006 Sex Transm Dis pmid:16572040
Hillis SD et al. Doxycycline and azithromycin for prevention of chlamydial persistence or recurrence one month after treatment in women. A use-effectiveness study in public health settings. 1998 Sex Transm Dis pmid:9437777
Dombrowski JC and Batteiger BE Reconsidering the Use of Azithromycin for Chlamydial Urethritis. 2016 Sex Transm Dis pmid:27626187
Handsfield HH Questioning azithromycin for chlamydial infection. 2011 Sex Transm Dis pmid:21992978
Stamm WE et al. A randomized, double-blind study comparing single-dose rifalazil with single-dose azithromycin for the empirical treatment of nongonococcal urethritis in men. 2007 Sex Transm Dis pmid:17297383