Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Psychomotor Agitation D011595 3 associated lipids
Superinfection D015163 3 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Digestive System Diseases D004066 3 associated lipids
Tendinopathy D052256 3 associated lipids
Corneal Edema D015715 3 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Retinal Hemorrhage D012166 3 associated lipids
Pemphigus D010392 3 associated lipids
Cryptosporidiosis D003457 3 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Mitral Valve Stenosis D008946 3 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Trichomonas Infections D014245 3 associated lipids
Uterine Cervicitis D002575 3 associated lipids
Bartonella Infections D001474 3 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Corneal Opacity D003318 3 associated lipids
Scrub Typhus D012612 3 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Aguirrebengoa K et al. [Endocarditis due to Bartonella henselae on a native valve. A new case with some notable aspects]. 2002 Enferm. Infecc. Microbiol. Clin. pmid:12372243
Paladino JA et al. Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia. 2002 Chest pmid:12377852
Ivashkin VT et al. Azithromycin in a triple therapy for H.pylori eradication in active duodenal ulcer. 2002 World J. Gastroenterol. pmid:12378634
Hauben M and Amsden GW The association of erythromycin and infantile hypertrophic pyloric stenosis: causal or coincidental? 2002 Drug Saf pmid:12381214
Itoh M et al. [A case of immotile-dyskinetic cilia syndrome responding to clenbuterol hydrochloride and azithromycin]. 2002 Nihon Kokyuki Gakkai Zasshi pmid:12382429
Equi A et al. Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial. 2002 Lancet pmid:12383667
Ohara T et al. Effects of azithromycin on shiga toxin production by Escherichia coli and subsequent host inflammatory response. 2002 Antimicrob. Agents Chemother. pmid:12384353
Sullivan B et al. Comparison of azithromycin and clarithromycin in triple therapy regimens for the eradication of Helicobacter pylori. 2002 Am. J. Gastroenterol. pmid:12385435
Brook I Antibacterial therapy for acute group a streptococcal pharyngotonsillitis: short-course versus traditional 10-day oral regimens. 2002 Paediatr Drugs pmid:12390046
Chandrupatla S et al. Azithromycin-induced intrahepatic cholestasis. 2002 Dig. Dis. Sci. pmid:12395890
Mileusnic D et al. Pathological case of the month: sudden death in a child as a result of pancreatitis during valproic acid therapy. 2002 Sep-Oct Pediatr Pathol Mol Med pmid:12396903
Shor A Atherosclerosis: lipid infiltration or Chlamydia pneumoniae infection? 2002 Circulation pmid:12403680
Orfila J et al. [Systematic screening for Chlamydia trachomatis with the molecular biological AMP-CT test in urine samples from young women]. 2002 J Gynecol Obstet Biol Reprod (Paris) pmid:12407326
Krolewiecki A et al. Activity of azithromycin against Leishmania major in vitro and in vivo. 2002 Am. J. Trop. Med. Hyg. pmid:12408666
Neumann FJ Chlamydia pneumoniae-atherosclerosis link: a sound concept in search for clinical relevance. 2002 Circulation pmid:12417534
Woolard S and Kenkel D Heading off antibiotic resistance. 2001 Adv Nurse Pract pmid:12420432
Skerk V et al. Comparative analysis of azithromycin and clarithromycin efficacy and tolerability in the treatment of chronic prostatitis caused by Chlamydia trachomatis. 2002 J Chemother pmid:12420857
Tambiah J and Powell JT Chlamydia pneumoniae antigens facilitate experimental aortic dilatation: prevention with azithromycin. 2002 J. Vasc. Surg. pmid:12422113
Arnez M et al. Solitary erythema migrans in children: comparison of treatment with azithromycin and phenoxymethylpenicillin. 2002 Wien. Klin. Wochenschr. pmid:12422590
Maraspin V et al. Development of erythema migrans in spite of treatment with antibiotics after a tick bite. 2002 Wien. Klin. Wochenschr. pmid:12422612
Hall IH et al. Disposition and intracellular activity of azithromycin in human THP-1 acute monocytes. 2002 Int. J. Antimicrob. Agents pmid:12431870
Kadappu KK et al. Azithromycin as treatment for cryptosporidiosis in human immunodeficiency virus disease. 2002 Jul-Sep J Postgrad Med pmid:12432190
Kamau FN et al. Isocratic liquid chromatographic method for the analysis of azithromycin and its structurally related substances in bulk samples. 2002 J Chromatogr Sci pmid:12433117
Pastor E et al. [Macrolide consumption according to geographic areas in the province of Valladolid]. 2002 Enferm. Infecc. Microbiol. Clin. pmid:12433351
Tyteca D et al. Azithromycin, a lysosomotropic antibiotic, has distinct effects on fluid-phase and receptor-mediated endocytosis, but does not impair phagocytosis in J774 macrophages. 2002 Exp. Cell Res. pmid:12441132
Di Paolo A et al. Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily. 2002 Pharmacol. Res. pmid:12457629
Chiu LM et al. Pharmacokinetics of intravenous azithromycin and ceftriaxone when administered alone and concurrently to healthy volunteers. 2002 J. Antimicrob. Chemother. pmid:12461037
Ranque S et al. Triangular test applied to the clinical trial of azithromycin against relapses in Plasmodium vivax infections. 2002 Malar. J. pmid:12473182
Hauke W et al. Esberitox N as supportive therapy when providing standard antibiotic treatment in subjects with a severe bacterial infection (acute exacerbation of chronic bronchitis). A multicentric, prospective, double-blind, placebo-controlled study. 2002 Chemotherapy pmid:12476043
Khan WA et al. Comparison of single-dose azithromycin and 12-dose, 3-day erythromycin for childhood cholera: a randomised, double-blind trial. 2002 Lancet pmid:12480424
Williams K Patient-delivered therapy: an additional means for addressing the Chlamydia trachomatis problem. 2002 Tenn Med pmid:12491815
Arreaza L et al. Emergence of gonococcal strains with resistance to azithromycin in Spain. 2003 J. Antimicrob. Chemother. pmid:12493814
Allam AF and Shehab AY Efficacy of azithromycin, praziquantel and mirazid in treatment of cryptosporidiosis in school children. 2002 J Egypt Soc Parasitol pmid:12512828
Schillinger JA et al. Patient-delivered partner treatment with azithromycin to prevent repeated Chlamydia trachomatis infection among women: a randomized, controlled trial. 2003 Sex Transm Dis pmid:12514443
Bogomil'skiÄ­ MP and Komarov RM [Azithromycin in the treatment of acute otitis media]. 2002 Antibiot. Khimioter. pmid:12515096
Hand WI and Hand DL [Mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes]. 2002 Antibiot. Khimioter. pmid:12516190
Kogan R et al. Comparative randomized trial of azithromycin versus erythromycin and amoxicillin for treatment of community-acquired pneumonia in children. 2003 Pediatr. Pulmonol. pmid:12526069
Schultz KD and Oermann CM Treatment of cast bronchitis with low-dose oral azithromycin. 2003 Pediatr. Pulmonol. pmid:12526076
Ewald DP et al. An evaluation of a SAFE-style trachoma control program in Central Australia. 2003 Med. J. Aust. pmid:12526724
Ovetchkine P and Cohen R Shortened course of antibacterial therapy for acute otitis media. 2003 Paediatr Drugs pmid:12529165
[Antibiotics in routine practice. With proper selection rapid success]. 2002 MMW Fortschr Med pmid:12532526
[Azithromycin for pediatric indications. Brief therapy is ideal for children]. 2002 MMW Fortschr Med pmid:12532527
Goswick SM and Brenner GM Activities of azithromycin and amphotericin B against Naegleria fowleri in vitro and in a mouse model of primary amebic meningoencephalitis. 2003 Antimicrob. Agents Chemother. pmid:12543653
Hoffman HL et al. Influence of macrolide susceptibility on efficacies of clarithromycin and azithromycin against Streptococcus pneumoniae in a murine lung infection model. 2003 Antimicrob. Agents Chemother. pmid:12543686
Javaloy J et al. Follicular conjunctivitis caused by Chlamydia trachomatis in an infant Saharan population: molecular and clinical diagnosis. 2003 Br J Ophthalmol pmid:12543737
Gaynor BD et al. Community treatment with azithromycin for trachoma is not associated with antibiotic resistance in Streptococcus pneumoniae at 1 year. 2003 Br J Ophthalmol pmid:12543738
Niv Y and Abuksis G Survey of the opinions, knowledge and practices of surgeons and internists regarding Helicobacter pylori test-and-treat policy. 2003 J. Clin. Gastroenterol. pmid:12544197
Knuf M et al. [Lymphadenitis colli due to non-tuberculous mycobacteria (NTM): a case-series and review of the literature]. 2003 Jan-Feb Klin Padiatr pmid:12545419
Sanchez JL et al. An outbreak of pneumococcal pneumonia among military personnel at high risk: control by low-dose azithromycin postexposure chemoprophylaxis. 2003 Mil Med pmid:12546236
Rekart ML et al. Targeted mass treatment for syphilis with oral azithromycin. 2003 Lancet pmid:12559870