Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Superinfection D015163 3 associated lipids
Pouchitis D019449 3 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Digestive System Diseases D004066 3 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Corneal Opacity D003318 3 associated lipids
Tendinopathy D052256 3 associated lipids
Retinal Hemorrhage D012166 3 associated lipids
Pemphigus D010392 3 associated lipids
Corneal Edema D015715 3 associated lipids
Cryptosporidiosis D003457 3 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Trichomonas Infections D014245 3 associated lipids
Uterine Cervicitis D002575 3 associated lipids
Mitral Valve Stenosis D008946 3 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Scrub Typhus D012612 3 associated lipids
Bartonella Infections D001474 3 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Weintraub A et al. In-vitro activity of solithromycin against anaerobic bacteria from the normal intestinal microbiota. 2016 Anaerobe pmid:27725229
Barrett B et al. Validated HPLC-MS-MS method for determination of azithromycin in human plasma. 2005 Anal Bioanal Chem pmid:16091946
Rufino JL et al. Flow-injection spectrophotometric determination of azithromycin in pharmaceutical formulations using p-chloranil in the presence of hydrogen peroxide. 2008 Anal Sci pmid:18614828
Galvidis I et al. Group determination of 14-membered macrolide antibiotics and azithromycin using antibodies against common epitopes. 2015 Anal. Biochem. pmid:25256165
Hemmateenejad B et al. Spectrophotometric study of complex formation equilibria in the presence of interference using hard-soft net analyte signal method: application to drug-metal complexation. 2011 Anal. Chim. Acta pmid:21167968
Zhang K et al. Facile synthesis of the necklace-like graphene oxide-multi-walled carbon nanotube nanohybrid and its application in electrochemical sensing of azithromycin. 2013 Anal. Chim. Acta pmid:23830420
Magri V et al. Eradication of Chlamydia trachomatis parallels symptom regression in chronic bacterial prostatitis patients treated with a fluoroquinolone-macrolide combination. 2010 Andrologia pmid:21105887
Kim HC and Kang SH Total synthesis of azithromycin. 2009 Angew. Chem. Int. Ed. Engl. pmid:19173267
O'Beirne SL et al. Trust Your Instincts. Surgical Lung Biopsy with Normal Chest Imaging in a 49-Year-Old Man with Progressive Dyspnea. 2016 Ann Am Thorac Soc pmid:27144798
McColley SA Practice guidelines, clinical trials, and unexpected results in cystic fibrosis. 2014 Ann Am Thorac Soc pmid:24673695
Cheng GS et al. Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant. 2016 Ann Am Thorac Soc pmid:27513368
Lee G et al. Nodular bronchiectatic Mycobacterium avium complex pulmonary disease. Natural course on serial computed tomographic scans. 2013 Ann Am Thorac Soc pmid:23952847
Nick JA et al. Azithromycin may antagonize inhaled tobramycin when targeting Pseudomonas aeruginosa in cystic fibrosis. 2014 Ann Am Thorac Soc pmid:24476418
Schmutz JL et al. [Skin eruptions due to azithromycin (Azadose-Zithromax) and infectious mononucleosis]. 2001 Ann Dermatol Venereol pmid:11395665
Foissac M et al. [Lymphangitis-associated rickettsiosis caused by Rickettsia sibirica mongolitimonae]. 2013 Aug-Sep Ann Dermatol Venereol pmid:24034636
Poizeau F et al. [Shifting cellulitis in a patient with X-linked hypogammaglobulinemia]. Ann Dermatol Venereol pmid:27080822
Foissac M et al. [Update on SENLAT syndrome: scalp eschar and neck lymph adenopathy after a tick bite]. 2013 Ann Dermatol Venereol pmid:24090889
Naji M et al. [An uncommon cutaneous presentation of cat scratch disease]. 2013 Ann Dermatol Venereol pmid:24090891
Schmutz JL et al. [Phenylbutazone and DRESS syndrome]. 2010 Ann Dermatol Venereol pmid:21134594
Mazereeuw-Hautier J [Impetigo]. 2006 Ann Dermatol Venereol pmid:16508614