Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Martin DH et al. | A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis. The Azithromycin for Chlamydial Infections Study Group. | 1992 | N. Engl. J. Med. | pmid:1325036 |
| Gingras BA and Jensen JB | Activity of azithromycin (CP-62,993) and erythromycin against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro. | 1992 | Am. J. Trop. Med. Hyg. | pmid:1326232 |
| Pajukanta R et al. | In vitro activity of azithromycin compared with that of erythromycin against Actinobacillus actinomycetemcomitans. | 1992 | Antimicrob. Agents Chemother. | pmid:1329617 |
| Bonnet M and Van der Auwera P | In vitro and in vivo intraleukocytic accumulation of azithromycin (CP-62, 993) and its influence on ex vivo leukocyte chemiluminescence. | 1992 | Antimicrob. Agents Chemother. | pmid:1329619 |
| Cynamon MH and Klemens SP | Activity of azithromycin against Mycobacterium avium infection in beige mice. | 1992 | Antimicrob. Agents Chemother. | pmid:1329622 |
| Ballow CH and Amsden GW | Azithromycin: the first azalide antibiotic. | 1992 | Ann Pharmacother | pmid:1330097 |
| Nilsen A et al. | A double blind study of single dose azithromycin and doxycycline in the treatment of chlamydial urethritis in males. | 1992 | Genitourin Med | pmid:1330880 |
| Jones AB and Herbert CM | The in vitro profile of selected 14-membered azalides. | 1992 | J. Antibiot. | pmid:1334956 |
| Frank MO et al. | In vitro demonstration of transport and delivery of antibiotics by polymorphonuclear leukocytes. | 1992 | Antimicrob. Agents Chemother. | pmid:1336337 |
| O'Reilly T et al. | Relationship between antibiotic concentration in bone and efficacy of treatment of staphylococcal osteomyelitis in rats: azithromycin compared with clindamycin and rifampin. | 1992 | Antimicrob. Agents Chemother. | pmid:1336342 |
| Lazarova Z et al. | Azithromycin (Sumamed-Pliva) in the treatment of chlamydial genital tract infections in infertile marriages. | 1992 Nov-Dec | Int J STD AIDS | pmid:1337473 |
| Farthing C et al. | Azithromycin for cerebral toxoplasmosis. | 1992 | Lancet | pmid:1346707 |
| Payton S et al. | Drug discovery targeted to the Alzheimer's APP mRNA 5'-untranslated region: the action of paroxetine and dimercaptopropanol. | 2003 | J. Mol. Neurosci. | pmid:14501007 |
| Arrieta A et al. | High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media. | 2003 | Antimicrob. Agents Chemother. | pmid:14506028 |
| Pichichero ME et al. | Azithromycin for the treatment of pertussis. | 2003 | Pediatr. Infect. Dis. J. | pmid:14515842 |
| Saiman L et al. | Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial. | 2003 | JAMA | pmid:14519709 |
| Odemis E et al. | Azithromycin-induced leukocytoclastic vasculitis. | 2003 | J. Rheumatol. | pmid:14528532 |
| Jennings MB et al. | Comparison of azithromycin and cefadroxil for the treatment of uncomplicated skin and skin structure infections. | 2003 | Cutis | pmid:14533837 |
| Adachi JA et al. | Azithromycin found to be comparable to levofloxacin for the treatment of US travelers with acute diarrhea acquired in Mexico. | 2003 | Clin. Infect. Dis. | pmid:14557959 |
| Szpakowski M and Szawłowski A | [Azithromycin (Sumamed) administration in empiric treatment of nosocomial pneumonia in upper digestive tract cancer patients]. | 2003 | Prz. Lek. | pmid:14575010 |
| Callaghan R and Allen M | Mycobacterium malmoense infection of the knee. | 2003 | Ann. Rheum. Dis. | pmid:14583565 |
| Niederman MS | [Conservative use of antibiotics is important, but: "Resistance hysteria is exaggerated"]. | 2003 | MMW Fortschr Med | pmid:14584217 |
| Cotter CJ and Bierne JC | Azithromycin for odontogenic infection. | 2003 | J. Oral Maxillofac. Surg. | pmid:14586869 |
| Mecaskey JW et al. | The possibility of eliminating blinding trachoma. | 2003 | Lancet Infect Dis | pmid:14592604 |
| Lobzin IuV et al. | [New achievements in the diagnosis and treatment of disseminated urogenital chlamydiosis]. | 2003 | Vestn. Akad. Med. Nauk SSSR | pmid:14598508 |
| Farley TA et al. | The acceptability and behavioral effects of antibiotic prophylaxis for syphilis prevention. | 2003 | Sex Transm Dis | pmid:14603093 |
| Nafar M et al. | A comparison between the efficacy of systemic and local azithromycin therapy in treatment of cyclosporine induced gingival overgrowth in kidney transplant patients. | 2003 | Transplant. Proc. | pmid:14612094 |
| Plouffe JF et al. | Azithromycin in the treatment of Legionella pneumonia requiring hospitalization. | 2003 | Clin. Infect. Dis. | pmid:14614670 |
| Matsunaga N et al. | A case of QT-interval prolongation precipitated by azithromycin. | 2003 | N. Z. Med. J. | pmid:14615808 |
| Purkins L et al. | No clinically significant effect of erythromycin or azithromycin on the pharmacokinetics of voriconazole in healthy male volunteers. | 2003 | Br J Clin Pharmacol | pmid:14616411 |
| Imbert P et al. | Eradication of multiresistant Salmonella Hadar convalescent-phase carriage with azithromycin. | 2003 | Clin. Microbiol. Infect. | pmid:14616738 |
| Owen WM et al. | Efficacy of azithromycin for the treatment of feline chlamydophilosis. | 2003 | J. Feline Med. Surg. | pmid:14623199 |
| Mandić Z et al. | Electrochemical oxidation of azithromycin and its derivatives. | 2003 | J Pharm Biomed Anal | pmid:14623590 |
| Muhlestein JB | Antibiotic treatment of atherosclerosis. | 2003 | Curr. Opin. Lipidol. | pmid:14624138 |
| Theaudin M et al. | [Extensive toxoplasmic retinochoroiditis. Diagnostic and therapeutic management]. | 2003 | J Fr Ophtalmol | pmid:14631276 |
| Song Z and Wang C | Ultrasensitive assay of azithromycin in medicine and bio-fluids based on its enhanced luminol-H(2)O(2) chemiluminescence reaction using flow injection technique. | 2003 | Bioorg. Med. Chem. | pmid:14642581 |
| Schriever C et al. | Red wine, resveratrol, Chlamydia pneumoniae and the French connection. | 2003 | Atherosclerosis | pmid:14644410 |
| Schilling F | [Chronic recurrent multifocal osteomyelitis. Opinion exchange concerning the article by T. Seidl et al in Der Orthopäde (2003) 32:535-540]. | 2003 | Orthopade | pmid:14655012 |
| Dobbin CJ and Bye PT | Adults with cystic fibrosis: meeting the challenge! | 2003 | Intern Med J | pmid:14656234 |
| Korppi M | Community-acquired pneumonia in children: issues in optimizing antibacterial treatment. | 2003 | Paediatr Drugs | pmid:14658923 |
| Nieuwenhuis RF et al. | Unusual presentation of early lymphogranuloma venereum in an HIV-1 infected patient: effective treatment with 1 g azithromycin. | 2003 | Sex Transm Infect | pmid:14663119 |
| Derelle J | [Anti-inflammatory therapy in cystic fibrosis]. | 2003 | Arch Pediatr | pmid:14671937 |
| Bernstein JM | The farmer and the tractor. | 2003 Mar-Apr | Skinmed | pmid:14673307 |
| Lederman HM et al. | Incomplete immune reconstitution after initiation of highly active antiretroviral therapy in human immunodeficiency virus-infected patients with severe CD4+ cell depletion. | 2003 | J. Infect. Dis. | pmid:14673757 |
| Aihara Y et al. | Stevens-Johnson syndrome associated with azithromycin followed by transient reactivation of herpes simplex virus infection. | 2004 | Allergy | pmid:14674950 |
| Enomoto T et al. | [Azithromycin therapy for patients with intractable diffuse panbronchiolitis]. | 2003 | Jpn J Antibiot | pmid:14679738 |
| Tateda K et al. | [Effects of azithromycin on pathogenic bacteria]. | 2003 | Jpn J Antibiot | pmid:14679740 |
| Shimizu T et al. | [Effect of azithromycin on mucus secretion from nasal epithelium]. | 2003 | Jpn J Antibiot | pmid:14679741 |
| Taira M et al. | [Effect of azithromycin on Cl ion transport in airway epithelial cells]. | 2003 | Jpn J Antibiot | pmid:14679742 |
| Sakata N et al. | [Influence of clarithromycin and azithromycin on cell cycle of neoplasms]. | 2003 | Jpn J Antibiot | pmid:14679743 |