Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Schmutz JL et al. | [Skin eruptions due to azithromycin (Azadose-Zithromax) and infectious mononucleosis]. | 2001 | Ann Dermatol Venereol | pmid:11395665 |
Schmutz JL et al. | [Azithromycin and Stevens-Johnson syndrome]. | 2005 Aug-Sep | Ann Dermatol Venereol | pmid:16230934 |
Clyti E et al. | [Short treatment of donovanosis with azithromycin]. | 2004 | Ann Dermatol Venereol | pmid:15235534 |
Foissac M et al. | [Update on SENLAT syndrome: scalp eschar and neck lymph adenopathy after a tick bite]. | 2013 | Ann Dermatol Venereol | pmid:24090889 |
Naji M et al. | [An uncommon cutaneous presentation of cat scratch disease]. | 2013 | Ann Dermatol Venereol | pmid:24090891 |
Schmutz JL et al. | [Phenylbutazone and DRESS syndrome]. | 2010 | Ann Dermatol Venereol | pmid:21134594 |
Mazereeuw-Hautier J | [Impetigo]. | 2006 | Ann Dermatol Venereol | pmid:16508614 |
de Oliveira Alves A et al. | Young Boy With Roughening in the Inner Eyelids. | 2018 | Ann Emerg Med | pmid:29458812 |
Conners GP and Hays DP | Emergency department drug orders: does drug storage location make a difference? | 2007 | Ann Emerg Med | pmid:17583377 |
Maldonado NG and Takhar SS | Update on Emerging Infections: news from the Centers for Disease Control and Prevention. Update to the CDC’s Sexually Transmitted Diseases Treatment Guidelines, 2010: Oral cephalosporins no longer a recommended treatment for gonococcal infections . | 2013 | Ann Emerg Med | pmid:23260686 |
Rao GA et al. | Azithromycin and levofloxacin use and increased risk of cardiac arrhythmia and death. | 2014 Mar-Apr | Ann Fam Med | pmid:24615307 |
Rim JH et al. | Recent Increase in the Incidence of TEM-135 β-Lactamase-harboring Neisseria gonorrhoeae in Korea. | 2018 | Ann Lab Med | pmid:29611382 |
Bouklouze A et al. | Azithromycin assay in drug formulations: Validation of a HPTLC method with a quadratic polynomial calibration model using the accuracy profile approach. | 2017 | Ann Pharm Fr | pmid:27692351 |
Law C and Amsden GW | Single-dose azithromycin for respiratory tract infections. | 2004 | Ann Pharmacother | pmid:14970367 |
Grunden JW and Fisher KA | Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin. | 1997 Jul-Aug | Ann Pharmacother | pmid:9220046 |
Luke DR and Foulds G | Toleration of intravenous azithromycin. | 1997 | Ann Pharmacother | pmid:9296232 |
Fraser LA et al. | Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. | 2015 | Ann Pharmacother | pmid:25429094 |
Garey KW and Amsden GW | Intravenous azithromycin. | 1999 | Ann Pharmacother | pmid:10084418 |
Ballow CH and Amsden GW | Azithromycin: the first azalide antibiotic. | 1992 | Ann Pharmacother | pmid:1330097 |
Carr RR and Nahata MC | Azithromycin for improving pulmonary function in cystic fibrosis. | 2004 | Ann Pharmacother | pmid:15213312 |
Wintermeyer SM et al. | Dirithromycin: a new macrolide. | 1996 | Ann Pharmacother | pmid:8893122 |
Rao KB et al. | Enhanced hypoprothrombinemia with warfarin due to azithromycin. | 2004 | Ann Pharmacother | pmid:15084685 |
Thompson DF and Ramos CL | Antibiotic-Induced Rash in Patients With Infectious Mononucleosis. | 2017 | Ann Pharmacother | pmid:27620494 |
Howard PA | Azithromycin-induced proarrhythmia and cardiovascular death. | 2013 | Ann Pharmacother | pmid:24285766 |
Renz CL and Ashraf T | Comment: cost-effectiveness of macrolides in lower respiratory tract infections. | 2000 | Ann Pharmacother | pmid:11054992 |
Amsden GW | Macrolides versus azalides: a drug interaction update. | 1995 | Ann Pharmacother | pmid:8547740 |
Woldtvedt BR et al. | Possible increased anticoagulation effect of warfarin induced by azithromycin. | 1998 | Ann Pharmacother | pmid:9496419 |
Bahal N and Nahata MC | The new macrolide antibiotics: azithromycin, clarithromycin, dirithromycin, and roxithromycin. | 1992 | Ann Pharmacother | pmid:1318761 |
Potter TG and Snider KR | Azithromycin for the treatment of gastroparesis. | 2013 | Ann Pharmacother | pmid:23447477 |
Burgess DS et al. | A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. | 1999 | Ann Pharmacother | pmid:10630825 |
Rapp RP | Pharmacokinetics and pharmacodynamics of intravenous and oral azithromycin: enhanced tissue activity and minimal drug interactions. | 1998 Jul-Aug | Ann Pharmacother | pmid:9681095 |
Zaremba CD | Comment: could acetaminophen have played a role in a possible azithromycin-warfarin interaction? | 1998 Jul-Aug | Ann Pharmacother | pmid:9681108 |
Hatton RC and Harbilas JW | Comment: Azithromycin for gastroparesis. | 2013 | Ann Pharmacother | pmid:23613098 |
Therriault BL et al. | Severe sepsis caused by Arcanobacterium haemolyticum: a case report and review of the literature. | 2008 | Ann Pharmacother | pmid:18812563 |
Cadle RM et al. | Symptomatic syndrome of inappropriate antidiuretic hormone secretion associated with azithromycin. | 1997 | Ann Pharmacother | pmid:9391684 |
Davis TM | Adverse effects of antimalarial prophylactic drugs: an important consideration in the risk-benefit equation. | 1998 | Ann Pharmacother | pmid:9793605 |
Rapp RP et al. | New macrolide antibiotics: usefulness in infections caused by mycobacteria other than Mycobacterium tuberculosis. | 1994 | Ann Pharmacother | pmid:7849341 |
Lane G | Increased hypoprothrombinemic effect of warfarin possibly induced by azithromycin. | 1996 Jul-Aug | Ann Pharmacother | pmid:8826581 |
Bessette RE and Amsden GW | Treatment of non-HIV cryptosporidial diarrhea with azithromycin. | 1995 | Ann Pharmacother | pmid:8845560 |
Riesselman A and El-Mallakh RS | Akathisia with azithromycin. | 2015 | Ann Pharmacother | pmid:25870444 |
Yang P et al. | Prevention of skin flap infection by transdermal penetration of azithromycin in rats. | 2013 | Ann Plast Surg | pmid:23392258 |
Simunić M et al. | Helicobacter pylori eradication for the treatment of dyspeptic symptoms in chronic renal failure. | 2005 Sep-Oct | Ann Saudi Med | pmid:16270770 |
Gryglicka B et al. | Evaluation of an anti-chlamydial antibiotic therapy influence on asthma patients. | 2003 | Ann Univ Mariae Curie Sklodowska Med | pmid:15315030 |
Romanowska-Sarlej J et al. | Ultrastructure of the hepatocytes after application of azithromycin (Sumamed). | 2004 | Ann Univ Mariae Curie Sklodowska Med | pmid:16146049 |
Lo KK et al. | An open non-comparative pilot study with azithromycin in the treatment of non-gonococcal urethritis in the sexually transmitted disease clinics in Hong Kong. | 1995 | Ann. Acad. Med. Singap. | pmid:8849186 |
Bottenberg MM et al. | Apparent anaphylactoid reaction after treatment with a single dose of telithromycin. | 2007 | Ann. Allergy Asthma Immunol. | pmid:17225726 |
Wu CC et al. | Association of acute urticaria with Mycoplasma pneumoniae infection in hospitalized children. | 2009 | Ann. Allergy Asthma Immunol. | pmid:19739426 |
Hahn DL et al. | Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9475566 |
Swamy N et al. | Successful clarithromycin desensitization in a multiple macrolide-allergic patient. | 2010 | Ann. Allergy Asthma Immunol. | pmid:21130389 |
Wareham DW and Bean DC | In-vitro activity of polymyxin B in combination with imipenem, rifampicin and azithromycin versus multidrug resistant strains of Acinetobacter baumannii producing OXA-23 carbapenemases. | 2006 | Ann. Clin. Microbiol. Antimicrob. | pmid:16630352 |
Brunner A et al. | Emerging azithromycin-resistance among the Neisseria gonorrhoeae strains isolated in Hungary. | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27646968 |
Akram FE et al. | A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27530257 |
Konstantinopoulos PA et al. | Babesiosis masquerading as recurrent immune thrombocytopenic purpura in a splenectomized patient. | 2006 | Ann. Hematol. | pmid:16705453 |
Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
Khan WA et al. | Treatment of shigellosis: V. Comparison of azithromycin and ciprofloxacin. A double-blind, randomized, controlled trial. | 1997 | Ann. Intern. Med. | pmid:9139555 |
Hook EW et al. | Azithromycin compared with penicillin G benzathine for treatment of incubating syphilis. | 1999 | Ann. Intern. Med. | pmid:10498560 |
Pursnani A et al. | Hypersensitivity myocarditis associated with azithromycin exposure. | 2009 | Ann. Intern. Med. | pmid:19189924 |
Wang SA et al. | Antimicrobial resistance for Neisseria gonorrhoeae in the United States, 1988 to 2003: the spread of fluoroquinolone resistance. | 2007 | Ann. Intern. Med. | pmid:17638718 |
Luft BJ et al. | Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial. | 1996 | Ann. Intern. Med. | pmid:8610947 |
Johnson JR | Therapy for Legionnaires disease. | 1999 | Ann. Intern. Med. | pmid:10366385 |
Neu HC | New macrolide antibiotics: azithromycin and clarithromycin. | 1992 | Ann. Intern. Med. | pmid:1310839 |
Sacks HS | In older adults, macrolide antibiotics were not linked to increased risk for ventricular arrhythmia. | 2016 | Ann. Intern. Med. | pmid:27323264 |
Magid D et al. | Doxycycline compared with azithromycin for treating women with genital Chlamydia trachomatis infections: an incremental cost-effectiveness analysis. | 1996 | Ann. Intern. Med. | pmid:8554247 |
Currier JS et al. | Discontinuation of Mycobacterium avium complex prophylaxis in patients with antiretroviral therapy-induced increases in CD4+ cell count. A randomized, double-blind, placebo-controlled trial. AIDS Clinical Trials Group 362 Study Team. | 2000 | Ann. Intern. Med. | pmid:11015162 |
Anderson SL et al. | Prophylaxis of Plasmodium falciparum malaria with azithromycin administered to volunteers. | 1995 | Ann. Intern. Med. | pmid:7574195 |
Kirkcaldy RD et al. | Neisseria gonorrhoeae antimicrobial resistance among men who have sex with men and men who have sex exclusively with women: the Gonococcal Isolate Surveillance Project, 2005-2010. | 2013 | Ann. Intern. Med. | pmid:23460055 |
Genç M and Mårdh A | A cost-effectiveness analysis of screening and treatment for Chlamydia trachomatis infection in asymptomatic women. | 1996 | Ann. Intern. Med. | pmid:7503471 |
Mansoor GA et al. | Azithromycin-induced acute interstitial nephritis. | 1993 | Ann. Intern. Med. | pmid:8395778 |
Glazer JL | Customer disservice? | 2006 | Ann. Intern. Med. | pmid:16389257 |
Stanbrook MB | Azithromycin reduced exacerbations and improved QoL in symptomatic asthma despite inhaled maintenance therapy. | 2017 | Ann. Intern. Med. | pmid:29049761 |
Ibarra V et al. | Effect of antibiotic treatment in patients with DEBONEL/TIBOLA. | 2005 | Ann. N. Y. Acad. Sci. | pmid:16481523 |
Ress BD and Gross EM | Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. | 2000 | Ann. Otol. Rhinol. Laryngol. | pmid:10778901 |
Mamikoglu B and Mamikoglu O | Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. | 2001 | Ann. Otol. Rhinol. Laryngol. | pmid:11201801 |
Callaghan R and Allen M | Mycobacterium malmoense infection of the knee. | 2003 | Ann. Rheum. Dis. | pmid:14583565 |
Kvien TK et al. | Three month treatment of reactive arthritis with azithromycin: a EULAR double blind, placebo controlled study. | 2004 | Ann. Rheum. Dis. | pmid:15308521 |
Carter JD et al. | Antimicrobial treatment for Chlamydia induced reactive arthritis. | 2005 | Ann. Rheum. Dis. | pmid:15708913 |
Nowicki M et al. | Partial regression of advanced cyclosporin-induced gingival hyperplasia after treatment with azithromycin. A case report. | 1998 | Ann. Transplant. | pmid:10234432 |
Mitrokhin SD et al. | [Susceptibility of community-acquired pneumonia pathogens to azithromycin]. | 1998 | Antibiot. Khimioter. | pmid:9606504 |
Andreeva IV et al. | [Diagnostic and treatment patterns in management of male patients with nongonococcal urethritis: results of Russian multicentral cross-sectional study]. | 2012 | Antibiot. Khimioter. | pmid:23156042 |
Sher AA et al. | [Interactions in the system of copper ion-azalide (azithromycin)]. | 1994 Sep-Oct | Antibiot. Khimioter. | pmid:7695446 |
Khrianin AA et al. | [Efficacy of azithromycin and its impact on cytokine system in urogenital infections]. | 2012 | Antibiot. Khimioter. | pmid:22993937 |
Suskova VS et al. | [Immuno-modulating properties of a macrolide antibiotic "Z-factor"]. | 2003 | Antibiot. Khimioter. | pmid:15002174 |
Bogomil'skiÄ MP and Komarov RM | [Azithromycin in the treatment of acute otitis media]. | 2002 | Antibiot. Khimioter. | pmid:12515096 |
Hand WI and Hand DL | [Mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes]. | 2002 | Antibiot. Khimioter. | pmid:12516190 |
ZaÄtseva EA et al. | [Comparative study of the antimicrobial activity of pefloxacin, ciprofloxacin, norfloxacin and azithromycin with respect to Strains of Yersinia pseudotuberculosis]. | 1996 | Antibiot. Khimioter. | pmid:8762820 |
Karpov OI | [The clinical and economic efficacies of short courses of azithromycin in acute sinusitis]. | 1999 | Antibiot. Khimioter. | pmid:10635419 |
Reshetniak VI et al. | [Eradication of Helicobacter pylori in patients with duodenal ulcer following the short course of treatment with azitromycin and amoxycillin]. | 2002 | Antibiot. Khimioter. | pmid:12087718 |
Bogdanov MB and Chernen'kaia TV | [Microbiological evaluation of antibiotics for empirical therapy of community-acquired infections of the lower respiratory tract]. | 2000 | Antibiot. Khimioter. | pmid:11212394 |
Budanov SV | [Azithromycin (sumamed)--basic properties and therapy of community-acquired pneumonia]. | 2000 | Antibiot. Khimioter. | pmid:11212397 |
Iur'ev SIu et al. | [Azithromycin levels in the chorion tissue within the first three months of the pregnancy term]. | 2004 | Antibiot. Khimioter. | pmid:15850052 |
Iakovlev SV and Ukhin SA | [Azithromycin: general properties and regimen optimization based on pharmacokinetic and pharmacological parameters]. | 2003 | Antibiot. Khimioter. | pmid:12803047 |
Gomberg MA and MashkilleÄson AL | [Use of azithromycin in long existing urogenital chlamydia infections and its association with primary syphilis]. | 1993 | Antibiot. Khimioter. | pmid:8060178 |
Sidorenko SV | [Azithromycin--an antibiotic of the azalide group]. | 1993 | Antibiot. Khimioter. | pmid:8060181 |
Lopatkin NA et al. | [Use of azithromycin ("Sumamded") in the treatment of infectious-inflammatory diseases of the lower urinary tract and male genitalia]. | 1993 | Antibiot. Khimioter. | pmid:8060189 |
Khrianin AA et al. | [Impact of exogenous proteolytic enzymes on immunogenesis in patients with urogenital infections]. | 2012 | Antibiot. Khimioter. | pmid:23477217 |
Khrianin AA and Reshetnikov OV | [Use of macrolides in pregnancy and lactation according to evidence-based medicine: pro et contra]. | 2010 | Antibiot. Khimioter. | pmid:21400756 |
Chulig I | [Pharmacokinetic profile of azithromycin. Role in the treatment of genital Chlamydia infections]. | 1996 | Antibiot. Khimioter. | pmid:8929112 |
Kuznetsova SM | ["Sumamed in the treatment of urogenital infections"]. | 1996 | Antibiot. Khimioter. | pmid:8929115 |
Skripkin IuK et al. | [The problem of diagnosis and treatment of urogenital chlamydiosis in Russia]. | 1996 | Antibiot. Khimioter. | pmid:8929120 |
Vasil'ev MM and Gazarian IIu | [Clinico-laboratory evaluation of the effectiveness of azithromycin in the treatment of patients with Chlamydia and mixed Chlamydia-gonorrhea infections]. | 1996 | Antibiot. Khimioter. | pmid:8929122 |