Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Karhu E et al. | Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. | 2017 | J. Nat. Prod. | pmid:29043803 |
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| Agarwal P et al. | susceptibility of Indian isolates to different antimalarial drugs & antibiotics. | 2017 | Indian J. Med. Res. | pmid:29512604 |
| Yang Z et al. | Azithromycin Causes a Novel Proarrhythmic Syndrome. | 2017 | Circ Arrhythm Electrophysiol | pmid:28408648 |
| Doan T et al. | Gut Microbial Diversity in Antibiotic-Naive Children After Systemic Antibiotic Exposure: A Randomized Controlled Trial. | 2017 | Clin. Infect. Dis. | pmid:28402408 |
| Husein-ElAhmed H | Single nontender ulcer on the glans. | 2017 | J Fam Pract | pmid:28375399 |
| Leeyaphan C et al. | Treatment Outcomes for Rectal Lymphogranuloma Venereum in Men Who Have Sex with Men Using Doxycycline, Azithromycin, or Both: A Review of Clinical Cases. | 2017 | Sex Transm Dis | pmid:28282652 |
| Ito S et al. | Haemophilus influenzae Isolated From Men With Acute Urethritis: Its Pathogenic Roles, Responses to Antimicrobial Chemotherapies, and Antimicrobial Susceptibilities. | 2017 | Sex Transm Dis | pmid:28282645 |
| Riddle MS et al. | Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. | 2017 | Clin. Infect. Dis. | pmid:29029033 |
| Alchakaki A et al. | Which patients with respiratory disease need long-term azithromycin? | 2017 | Cleve Clin J Med | pmid:28985171 |
| Senilă S et al. | Infliximab-induced acne and acute localized exanthematous pustulosis: Case report. | 2017 | Dermatol Ther | pmid:28976720 |
| Li Y et al. | Synergistic Activity of Berberine with Azithromycin against Pseudomonas Aeruginosa Isolated from Patients with Cystic Fibrosis of Lung In Vitro and In Vivo. | 2017 | Cell. Physiol. Biochem. | pmid:28738346 |
| Llop CJ et al. | Antibiotic treatment patterns, costs, and resource utilization among patients with community acquired pneumonia: a US cohort study. | 2017 | Hosp Pract (1995) | pmid:28064542 |
| West SK et al. | Treating village newcomers and travelers for trachoma: Results from ASANTE cluster randomized trial. | 2017 | PLoS ONE | pmid:28662043 |
| Johnson SR et al. | Use of whole-genome sequencing data to analyze 23S rRNA-mediated azithromycin resistance. | 2017 | Int. J. Antimicrob. Agents | pmid:28038960 |
| Sanders AM et al. | Burden of trachoma in five counties of Eastern Equatoria state, South Sudan: Results from population-based surveys. | 2017 | PLoS Negl Trop Dis | pmid:28614375 |
| Allen G | Evidence appraisal of Tita ATN, Szychowski JM, Boggess K, et al. Adjunctive azithromycin prophylaxis for cesarean delivery.: N Engl J Med. 2016;375:1231-1241. | 2017 | AORN J | pmid:28034388 |
| Jiang FX et al. | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Hefei (2014-2015): genetic characteristics of antimicrobial resistance. | 2017 | BMC Infect. Dis. | pmid:28545411 |
| Park J et al. | Progression and Treatment Outcomes of Lung Disease Caused by Mycobacterium abscessus and Mycobacterium massiliense. | 2017 | Clin. Infect. Dis. | pmid:28011609 |
| Karalius VP et al. | Bordetella parapertussis outbreak in Southeastern Minnesota and the United States, 2014. | 2017 | Medicine (Baltimore) | pmid:28514288 |
| Read TR et al. | Azithromycin 1.5g Over 5 Days Compared to 1g Single Dose in Urethral Mycoplasma genitalium: Impact on Treatment Outcome and Resistance. | 2017 | Clin. Infect. Dis. | pmid:28011607 |
| Vodstrcil LA et al. | Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS). | 2017 | PLoS ONE | pmid:28498845 |
| Schwameis M et al. | Topical azithromycin for the prevention of Lyme borreliosis: a randomised, placebo-controlled, phase 3 efficacy trial. | 2017 | Lancet Infect Dis | pmid:28007428 |
| Houinei W et al. | Haemophilus ducreyi DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea. | 2017 | PLoS Negl Trop Dis | pmid:28489855 |
| Gensel JC et al. | Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment. | 2017 | Sci Rep | pmid:28057928 |
| Szczepanska B et al. | Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. | 2017 | BMC Microbiol. | pmid:28376713 |
| Sutton SS | Is cardiovascular risk a concern when prescribing azithromycin? | 2017 | JAAPA | pmid:28033168 |
| Shapiro ED and Wormser GP | Prophylaxis with topical azithromycin against Lyme borreliosis. | 2017 | Lancet Infect Dis | pmid:28007427 |
| Seyama S et al. | Emergence and molecular characterization of Haemophilus influenzae harbouring mef(A). | 2017 | J. Antimicrob. Chemother. | pmid:27999037 |
| Kawamura K et al. | Azithromycin for idiopathic acute exacerbation of idiopathic pulmonary fibrosis: a retrospective single-center study. | 2017 | BMC Pulm Med | pmid:28629448 |
| Nozawa H et al. | Pertussis without apparent cough in a disabled girl with a tracheostomy. | 2017 | J. Infect. Chemother. | pmid:28623110 |
| Tsubouchi K et al. | Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4. | 2017 | Autophagy | pmid:28613983 |
| Smith KS et al. | Biological and Behavioral Factors Associated With Positive Chlamydia Retests. | 2017 | Sex Transm Dis | pmid:28608791 |
| Wind CM et al. | Decreased Azithromycin Susceptibility of Neisseria gonorrhoeae Isolates in Patients Recently Treated with Azithromycin. | 2017 | Clin. Infect. Dis. | pmid:28510723 |
| van Wagensveld L et al. | [Persistent, therapy-resistant conjunctivitis: consider infection with Chlamydia trachomatis]. | 2017 | Ned Tijdschr Geneeskd | pmid:28443807 |
| Manesh A et al. | A case of clinical and microbiological failure of azithromycin therapy in Salmonella enterica serotype Typhi despite low azithromycin MIC. | 2017 | Int. J. Infect. Dis. | pmid:27894983 |
| Zhang Y et al. | Novel Detection Strategy To Rapidly Evaluate the Efficacy of Antichlamydial Agents. | 2017 | Antimicrob. Agents Chemother. | pmid:27855081 |
| Waites KB et al. | In Vitro Activities of Lefamulin and Other Antimicrobial Agents against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China. | 2017 | Antimicrob. Agents Chemother. | pmid:27855075 |
| Jakubů V et al. | Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. | 2017 | Cent. Eur. J. Public Health | pmid:29346850 |
| Atkinson CT et al. | Expression of acquired macrolide resistance genes in Haemophilus influenzae. | 2017 | J. Antimicrob. Chemother. | pmid:28961896 |
| Menzel M et al. | Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. | 2017 | Oncotarget | pmid:28415826 |
| Kneidinger N et al. | Lung volumes predict survival in patients with chronic lung allograft dysfunction. | 2017 | Eur. Respir. J. | pmid:28404648 |
| Venekamp RP and Schilder AGM | Clinical failure is more common in young children with acute otitis media who receive a short course of antibiotics compared with standard duration. | 2017 | Evid Based Med | pmid:28404603 |
| Ma Q et al. | A Waterborne Outbreak of Shigella sonnei with Resistance to Azithromycin and Third-Generation Cephalosporins in China in 2015. | 2017 | Antimicrob. Agents Chemother. | pmid:28373192 |
| Wind CM et al. | A Case-Control Study of Molecular Epidemiology in Relation to Azithromycin Resistance in Neisseria gonorrhoeae Isolates Collected in Amsterdam, the Netherlands, between 2008 and 2015. | 2017 | Antimicrob. Agents Chemother. | pmid:28373191 |
| Watson JR et al. | Healthcare Claims Data: An Underutilized Tool for Pediatric Outpatient Antimicrobial Stewardship. | 2017 | Clin. Infect. Dis. | pmid:28329388 |
| Fuji S | Azithromycin and Survival After Hematopoietic Stem Cell Transplant. | 2017 | JAMA | pmid:29279920 |
| Castelli G et al. | PURLs: Does azithromycin have a role in cesarean sections? | 2017 | J Fam Pract | pmid:29202146 |
| Skeith AE et al. | Adding Azithromycin to Cephalosporin for Cesarean Delivery Infection Prophylaxis: A Cost-Effectiveness Analysis. | 2017 | Obstet Gynecol | pmid:29112658 |
| Stanbrook MB | Azithromycin reduced exacerbations and improved QoL in symptomatic asthma despite inhaled maintenance therapy. | 2017 | Ann. Intern. Med. | pmid:29049761 |