Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Airway Obstruction D000402 13 associated lipids
Urticaria D014581 13 associated lipids
Rosacea D012393 13 associated lipids
Abscess D000038 13 associated lipids
Sarcoidosis D012507 13 associated lipids
Otitis Media D010033 12 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Endophthalmitis D009877 12 associated lipids
Skin Neoplasms D012878 12 associated lipids
Eye Diseases D005128 12 associated lipids
Cat Diseases D002371 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Crohn Disease D003424 12 associated lipids
Wound Infection D014946 12 associated lipids
Shock, Septic D012772 11 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Exanthema D005076 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Karhu E et al. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. 2017 J. Nat. Prod. pmid:29043803
Mei J et al. Implications of intrapartum azithromycin on neonatal microbiota. 2017 Lancet Infect Dis pmid:28244378
Zhang M et al. Electrophysiologic Studies on the Risks and Potential Mechanism Underlying the Proarrhythmic Nature of Azithromycin. 2017 Cardiovasc. Toxicol. pmid:28213753
Lahra MM et al. Treatment guidelines after an outbreak of azithromycin-resistant Neisseria gonorrhoeae in South Australia. 2017 Lancet Infect Dis pmid:28134103
Koštrun S et al. Around the macrolide - Impact of 3D structure of macrocycles on lipophilicity and cellular accumulation. 2017 Eur J Med Chem pmid:28410508
Yang Z et al. Azithromycin Causes a Novel Proarrhythmic Syndrome. 2017 Circ Arrhythm Electrophysiol pmid:28408648
Doan T et al. Gut Microbial Diversity in Antibiotic-Naive Children After Systemic Antibiotic Exposure: A Randomized Controlled Trial. 2017 Clin. Infect. Dis. pmid:28402408
Husein-ElAhmed H Single nontender ulcer on the glans. 2017 J Fam Pract pmid:28375399
Leeyaphan C et al. Treatment Outcomes for Rectal Lymphogranuloma Venereum in Men Who Have Sex with Men Using Doxycycline, Azithromycin, or Both: A Review of Clinical Cases. 2017 Sex Transm Dis pmid:28282652
Subedi Y Around Manaslu Ultramarathon: Diarrhea Is Still the King. 2017 Wilderness Environ Med pmid:28735656
McConnell K and Shields M Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years. 2017 Arch Dis Child Educ Pract Ed pmid:28735295
Gibson PG et al. Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. 2017 Lancet pmid:28687413
Molefe NI et al. Oral administration of azithromycin ameliorates trypanosomosis in Trypanosoma congolense-infected mice. 2017 Parasitol. Res. pmid:28674747
Li Y et al. Synergistic Activity of Berberine with Azithromycin against Pseudomonas Aeruginosa Isolated from Patients with Cystic Fibrosis of Lung In Vitro and In Vivo. 2017 Cell. Physiol. Biochem. pmid:28738346
Llop CJ et al. Antibiotic treatment patterns, costs, and resource utilization among patients with community acquired pneumonia: a US cohort study. 2017 Hosp Pract (1995) pmid:28064542
West SK et al. Treating village newcomers and travelers for trachoma: Results from ASANTE cluster randomized trial. 2017 PLoS ONE pmid:28662043
Johnson SR et al. Use of whole-genome sequencing data to analyze 23S rRNA-mediated azithromycin resistance. 2017 Int. J. Antimicrob. Agents pmid:28038960
Sanders AM et al. Burden of trachoma in five counties of Eastern Equatoria state, South Sudan: Results from population-based surveys. 2017 PLoS Negl Trop Dis pmid:28614375
Allen G Evidence appraisal of Tita ATN, Szychowski JM, Boggess K, et al. Adjunctive azithromycin prophylaxis for cesarean delivery.: N Engl J Med. 2016;375:1231-1241. 2017 AORN J pmid:28034388
Jiang FX et al. Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Hefei (2014-2015): genetic characteristics of antimicrobial resistance. 2017 BMC Infect. Dis. pmid:28545411
Park J et al. Progression and Treatment Outcomes of Lung Disease Caused by Mycobacterium abscessus and Mycobacterium massiliense. 2017 Clin. Infect. Dis. pmid:28011609
Karalius VP et al. Bordetella parapertussis outbreak in Southeastern Minnesota and the United States, 2014. 2017 Medicine (Baltimore) pmid:28514288
Read TR et al. Azithromycin 1.5g Over 5 Days Compared to 1g Single Dose in Urethral Mycoplasma genitalium: Impact on Treatment Outcome and Resistance. 2017 Clin. Infect. Dis. pmid:28011607
Vodstrcil LA et al. Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS). 2017 PLoS ONE pmid:28498845
Schwameis M et al. Topical azithromycin for the prevention of Lyme borreliosis: a randomised, placebo-controlled, phase 3 efficacy trial. 2017 Lancet Infect Dis pmid:28007428
Szczepanska B et al. Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. 2017 BMC Microbiol. pmid:28376713
Koetsveld J et al. Susceptibility of the Relapsing-Fever Spirochete Borrelia miyamotoi to Antimicrobial Agents. 2017 Antimicrob. Agents Chemother. pmid:28674060
Kawamura K et al. Azithromycin for idiopathic acute exacerbation of idiopathic pulmonary fibrosis: a retrospective single-center study. 2017 BMC Pulm Med pmid:28629448
Nozawa H et al. Pertussis without apparent cough in a disabled girl with a tracheostomy. 2017 J. Infect. Chemother. pmid:28623110
Tsubouchi K et al. Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4. 2017 Autophagy pmid:28613983
Smith KS et al. Biological and Behavioral Factors Associated With Positive Chlamydia Retests. 2017 Sex Transm Dis pmid:28608791
Wind CM et al. Decreased Azithromycin Susceptibility of Neisseria gonorrhoeae Isolates in Patients Recently Treated with Azithromycin. 2017 Clin. Infect. Dis. pmid:28510723
van Wagensveld L et al. [Persistent, therapy-resistant conjunctivitis: consider infection with Chlamydia trachomatis]. 2017 Ned Tijdschr Geneeskd pmid:28443807
Bouklouze A et al. Azithromycin assay in drug formulations: Validation of a HPTLC method with a quadratic polynomial calibration model using the accuracy profile approach. 2017 Ann Pharm Fr pmid:27692351
Collins SA et al. Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms. 2017 Antimicrob. Agents Chemother. pmid:27919896
Manesh A et al. A case of clinical and microbiological failure of azithromycin therapy in Salmonella enterica serotype Typhi despite low azithromycin MIC. 2017 Int. J. Infect. Dis. pmid:27894983
Zhang Y et al. Novel Detection Strategy To Rapidly Evaluate the Efficacy of Antichlamydial Agents. 2017 Antimicrob. Agents Chemother. pmid:27855081
Jakubů V et al. Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. 2017 Cent. Eur. J. Public Health pmid:29346850
Jover-García J et al. [In-vitro activity of azithromycin in faecal isolates of Aeromonas hydrophila]. 2017 An Pediatr (Barc) pmid:27686393
Han B et al. Intrahepatic cholestasis of pregnancy or azithromycin-induced intrahepatic cholestasis: A case report. 2017 Medicine (Baltimore) pmid:29384912
Park HS et al. Subantibiotic dose of azithromycin attenuates alveolar bone destruction and improves trabecular microarchitectures in a rat model of experimental periodontitis: A study using micro-computed tomography. 2017 Int. Immunopharmacol. pmid:28432937
Menzel M et al. Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. 2017 Oncotarget pmid:28415826
Kneidinger N et al. Lung volumes predict survival in patients with chronic lung allograft dysfunction. 2017 Eur. Respir. J. pmid:28404648
Venekamp RP and Schilder AGM Clinical failure is more common in young children with acute otitis media who receive a short course of antibiotics compared with standard duration. 2017 Evid Based Med pmid:28404603
Ma Q et al. A Waterborne Outbreak of Shigella sonnei with Resistance to Azithromycin and Third-Generation Cephalosporins in China in 2015. 2017 Antimicrob. Agents Chemother. pmid:28373192
Wind CM et al. A Case-Control Study of Molecular Epidemiology in Relation to Azithromycin Resistance in Neisseria gonorrhoeae Isolates Collected in Amsterdam, the Netherlands, between 2008 and 2015. 2017 Antimicrob. Agents Chemother. pmid:28373191
Fuji S Azithromycin and Survival After Hematopoietic Stem Cell Transplant. 2017 JAMA pmid:29279920
Castelli G et al. PURLs: Does azithromycin have a role in cesarean sections? 2017 J Fam Pract pmid:29202146
Skeith AE et al. Adding Azithromycin to Cephalosporin for Cesarean Delivery Infection Prophylaxis: A Cost-Effectiveness Analysis. 2017 Obstet Gynecol pmid:29112658
Stanbrook MB Azithromycin reduced exacerbations and improved QoL in symptomatic asthma despite inhaled maintenance therapy. 2017 Ann. Intern. Med. pmid:29049761