Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Multiple Myeloma D009101 13 associated lipids
Pain, Postoperative D010149 13 associated lipids
Airway Obstruction D000402 13 associated lipids
Urticaria D014581 13 associated lipids
Rosacea D012393 13 associated lipids
Wound Infection D014946 12 associated lipids
Otitis Media D010033 12 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Skin Neoplasms D012878 12 associated lipids
Endophthalmitis D009877 12 associated lipids
Eye Diseases D005128 12 associated lipids
Cat Diseases D002371 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Crohn Disease D003424 12 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Exanthema D005076 11 associated lipids
Shock, Septic D012772 11 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Urinary Tract Infections D014552 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Karhu E et al. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. 2017 J. Nat. Prod. pmid:29043803
Tuite AR et al. Impact of Rapid Susceptibility Testing and Antibiotic Selection Strategy on the Emergence and Spread of Antibiotic Resistance in Gonorrhea. 2017 J. Infect. Dis. pmid:28968710
Trembizki E et al. High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia. 2017 J. Med. Microbiol. pmid:28893363
Bystrzycka W et al. Azithromycin and Chloramphenicol Diminish Neutrophil Extracellular Traps (NETs) Release. 2017 Int J Mol Sci pmid:29292737
Pavlinac PB et al. Azithromycin to prevent post-discharge morbidity and mortality in Kenyan children: a protocol for a randomised, double-blind, placebo-controlled trial (the Toto Bora trial). 2017 BMJ Open pmid:29289941
Last AR et al. The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma-endemic island communities in West Africa. 2017 Parasit Vectors pmid:29282126
Leeyaphan C et al. Treatment Outcomes for Rectal Lymphogranuloma Venereum in Men Who Have Sex with Men Using Doxycycline, Azithromycin, or Both: A Review of Clinical Cases. 2017 Sex Transm Dis pmid:28282652
Ito S et al. Haemophilus influenzae Isolated From Men With Acute Urethritis: Its Pathogenic Roles, Responses to Antimicrobial Chemotherapies, and Antimicrobial Susceptibilities. 2017 Sex Transm Dis pmid:28282645
Stieler Stewart AL et al. Effects of clarithromycin, azithromycin and rifampicin on terbutaline-induced sweating in foals. 2017 Equine Vet. J. pmid:28238211
Allan RN et al. Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms. 2017 Nitric Oxide pmid:28235635
Cluver C et al. Interventions for treating genital Chlamydia trachomatis infection in pregnancy. 2017 Cochrane Database Syst Rev pmid:28937705
Batteiger BE Azithromycin Efficacy in Asymptomatic Rectal Chlamydial Infection in Men Who Have Sex With Men: A More Definitive Answer Soon? 2017 Sex Transm Dis pmid:28604482
Sonavane AD and Rathi PM Fitz-Hugh-Curtis syndrome. 2017 Indian J. Med. Res. pmid:28574030
Ra SW et al. Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. 2017 Respir. Res. pmid:28558695
Vodstrcil LA et al. Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS). 2017 PLoS ONE pmid:28498845
Schwameis M et al. Topical azithromycin for the prevention of Lyme borreliosis: a randomised, placebo-controlled, phase 3 efficacy trial. 2017 Lancet Infect Dis pmid:28007428
Houinei W et al. Haemophilus ducreyi DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea. 2017 PLoS Negl Trop Dis pmid:28489855
Nenoff P et al. [Non-viral sexually transmitted infections - Epidemiology, clinical manifestations, diagnostics and therapy : Part 1: Gonococci]. 2017 Hautarzt pmid:27981386
Rutenberg D et al. Efficacy of Tulathromycin for the Treatment of Foals with Mild to Moderate Bronchopneumonia. 2017 J. Vet. Intern. Med. pmid:28421633
Trifirò G et al. Use of azithromycin and risk of ventricular arrhythmia. 2017 CMAJ pmid:28420680
Amza A et al. A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children. 2017 Clin. Infect. Dis. pmid:27956455
Smith KS et al. Biological and Behavioral Factors Associated With Positive Chlamydia Retests. 2017 Sex Transm Dis pmid:28608791
Wind CM et al. Decreased Azithromycin Susceptibility of Neisseria gonorrhoeae Isolates in Patients Recently Treated with Azithromycin. 2017 Clin. Infect. Dis. pmid:28510723
van Wagensveld L et al. [Persistent, therapy-resistant conjunctivitis: consider infection with Chlamydia trachomatis]. 2017 Ned Tijdschr Geneeskd pmid:28443807
Foerster S et al. A new rapid resazurin-based microdilution assay for antimicrobial susceptibility testing of Neisseria gonorrhoeae. 2017 J. Antimicrob. Chemother. pmid:28431096
Zhang Y et al. Novel Detection Strategy To Rapidly Evaluate the Efficacy of Antichlamydial Agents. 2017 Antimicrob. Agents Chemother. pmid:27855081
Waites KB et al. In Vitro Activities of Lefamulin and Other Antimicrobial Agents against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China. 2017 Antimicrob. Agents Chemother. pmid:27855075
Thompson DF and Ramos CL Antibiotic-Induced Rash in Patients With Infectious Mononucleosis. 2017 Ann Pharmacother pmid:27620494
Rajesh AM and Popat KM Taste masking of azithromycin by resin complex and sustained release through interpenetrating polymer network with functionalized biopolymers. 2017 Drug Dev Ind Pharm pmid:27600608
Dror T et al. Microbiota manipulation for weight change. 2017 Microb. Pathog. pmid:26792677
Burr SE et al. Does azithromycin given to women in labour decrease ocular bacterial infection in neonates? A double-blind, randomized trial. 2017 BMC Infect. Dis. pmid:29282015
Wind CM et al. A Case-Control Study of Molecular Epidemiology in Relation to Azithromycin Resistance in Neisseria gonorrhoeae Isolates Collected in Amsterdam, the Netherlands, between 2008 and 2015. 2017 Antimicrob. Agents Chemother. pmid:28373191
Watson JR et al. Healthcare Claims Data: An Underutilized Tool for Pediatric Outpatient Antimicrobial Stewardship. 2017 Clin. Infect. Dis. pmid:28329388
Thompson CN et al. Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal. 2017 Clin. Infect. Dis. pmid:28329181
Emerging risk of untreatable gonorrhea and what to do about it. 2017 Can Fam Physician pmid:28292798
Stanbrook MB Azithromycin reduced exacerbations and improved QoL in symptomatic asthma despite inhaled maintenance therapy. 2017 Ann. Intern. Med. pmid:29049761
Diniz LM et al. Bacillary angiomatosis with bone invasion. 2016 Nov-Dec An Bras Dermatol pmid:28099606
Akoglu G et al. Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. 2016 May-Jun Indian J Pharmacol pmid:27298507
Latif SA et al. Azithromycin buccal patch in treatment of chronic periodontitis. 2016 Mar-Apr Indian J Pharmacol pmid:27127325
Oliveira IS et al. Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. 2016 Mar-Apr Braz J Otorhinolaryngol pmid:26601998
Chatterjee S et al. Azithromycin susceptibility among clinical isolates of Salmonella: Interfacing guidelines with routine practices. 2016 Jul-Sep Indian J Med Microbiol pmid:27514976
Hazra A Author Reply. 2016 Jan-Feb Indian J Pharmacol pmid:26997735
Das S and Mohanty M Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. 2016 Jan-Feb Indian J Pharmacol pmid:26997734
Das A et al. Azithromycin induced bullous fixed drug eruption. 2016 Jan-Feb Indian J Pharmacol pmid:26997729
Nair S et al. WGS for surveillance of antimicrobial resistance: a pilot study to detect the prevalence and mechanism of resistance to azithromycin in a UK population of non-typhoidal Salmonella. 2016 J. Antimicrob. Chemother. pmid:27585964
Mwingira UJ et al. Progress of Trachoma Mapping in Mainland Tanzania: Results of Baseline Surveys from 2012 to 2014. 2016 Ophthalmic Epidemiol pmid:27775455
Horner PJ et al. 2016 European guideline on the management of non-gonococcal urethritis. 2016 Int J STD AIDS pmid:27147267
El-Shitany NA and El-Desoky K Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-β, and TNF-α Production and Inhibiting NF-κB and Caspase-3 Expression. 2016 Oxid Med Cell Longev pmid:27274777
Marks M et al. Mass drug administration of azithromycin for trachoma reduces the prevalence of genital Chlamydia trachomatis infection in the Solomon Islands. 2016 Sex Transm Infect pmid:26888658
Nicholson TT et al. Assessing potential risks of treatment with long-term azithromycin in COPD patients: long-term oxygen users beware? 2016 Ir J Med Sci pmid:26502012