Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Chronic Disease D002908 7 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Keratitis D007634 7 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Gonorrhea D006069 7 associated lipids
Serum Sickness D012713 7 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Mucositis D052016 7 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Enteritis D004751 8 associated lipids
Leprosy D007918 8 associated lipids
Opportunistic Infections D009894 8 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Cross Infection D003428 9 associated lipids
Urethritis D014526 9 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Sinusitis D012852 9 associated lipids
Toxoplasmosis D014123 9 associated lipids
Rhabdomyolysis D012206 9 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Keratosis D007642 9 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Osteitis D010000 10 associated lipids
Hearing Disorders D006311 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Long QT Syndrome D008133 10 associated lipids
Pancreatitis D010195 10 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Dyspnea D004417 10 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Exanthema D005076 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Malizia T et al. Periodontal tissue disposition of azithromycin. 1997 J. Periodontol. pmid:9444596
Nguyen MH et al. Potentiation of antifungal activity of amphotericin B by azithromycin against Aspergillus species. 1997 Eur. J. Clin. Microbiol. Infect. Dis. pmid:9447909
Bermudez LE et al. Emergence of Mycobacterium avium populations resistant to macrolides during experimental chemotherapy. 1998 Antimicrob. Agents Chemother. pmid:9449283
Roblin PM and Hammerschlag MR Microbiologic efficacy of azithromycin and susceptibilities to azithromycin of isolates of Chlamydia pneumoniae from adults and children with community-acquired pneumonia. 1998 Antimicrob. Agents Chemother. pmid:9449287
Diculencu D et al. [The postantibiotic effect of azithromycin on respiratory pathogens]. 1996 Jul-Dec Rev Med Chir Soc Med Nat Iasi pmid:9455450
Gray GC et al. Weekly oral azithromycin as prophylaxis for agents causing acute respiratory disease. 1998 Clin. Infect. Dis. pmid:9455517
Andersen SL et al. Successful double-blinded, randomized, placebo-controlled field trial of azithromycin and doxycycline as prophylaxis for malaria in western Kenya. 1998 Clin. Infect. Dis. pmid:9455524
Chia JK et al. Azithromycin for the treatment of cat-scratch disease. 1998 Clin. Infect. Dis. pmid:9455538
Peterson J and Treadway G Impact of community-based azithromycin treatment of trachoma on carriage and resistance of Streptococcus pneumoniae. 1998 Clin. Infect. Dis. pmid:9455579
Holmberg SD et al. Possible effectiveness of clarithromycin and rifabutin for cryptosporidiosis chemoprophylaxis in HIV disease. HIV Outpatient Study (HOPS) Investigators. 1998 JAMA pmid:9459473
Gaydos CA et al. Molecular amplification assays to detect chlamydial infections in urine specimens from high school female students and to monitor the persistence of chlamydial DNA after therapy. 1998 J. Infect. Dis. pmid:9466530
Adair CD et al. Chlamydia in pregnancy: a randomized trial of azithromycin and erythromycin. 1998 Obstet Gynecol pmid:9469269
Vcev A et al. [Omeprazole and azithromycin with and without metronidazole in the eradication of Helicobacter pylori in duodenal ulcer disease]. 1997 Lijec Vjesn pmid:9471481
Lilley LL and Guanci R Distraction delays a dose. 1998 Am J Nurs pmid:9473978
Hahn DL et al. Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. 1998 Ann. Allergy Asthma Immunol. pmid:9475566
Jaffé A et al. Long-term azithromycin may improve lung function in children with cystic fibrosis. 1998 Lancet pmid:9482305
Russell TS et al. Eradication of Cryptosporidium in a child undergoing maintenance chemotherapy for leukemia using high dose azithromycin therapy. 1998 Jan-Feb J. Pediatr. Hematol. Oncol. pmid:9482419
Seelis RE and Dohmen W [Short-term (6 days) eradication of Helicobacter pylori infection in the practice of a health insurance physician]. 1998 Dtsch. Med. Wochenschr. pmid:9487294
Thalhammer F et al. Azithromycin-related toxic effects of digitoxin. 1998 Br J Clin Pharmacol pmid:9489601
Muhlestein JB et al. Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. 1998 Circulation pmid:9495296