Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Genital Diseases, Female D005831 7 associated lipids
Keratitis D007634 7 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Gonorrhea D006069 7 associated lipids
Serum Sickness D012713 7 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Mucositis D052016 7 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Chlamydia Infections D002690 7 associated lipids
Pelvic Pain D017699 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Leprosy D007918 8 associated lipids
Opportunistic Infections D009894 8 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Enteritis D004751 8 associated lipids
Cross Infection D003428 9 associated lipids
Urethritis D014526 9 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Sinusitis D012852 9 associated lipids
Toxoplasmosis D014123 9 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Keratosis D007642 9 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Hearing Disorders D006311 10 associated lipids
Pancreatitis D010195 10 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Long QT Syndrome D008133 10 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Osteitis D010000 10 associated lipids
Dyspnea D004417 10 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Exanthema D005076 11 associated lipids
Shock, Septic D012772 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Brkljacić N et al. Stevens-Johnson syndrome as an unusual adverse effect of azithromycin. 2006 Acta Dermatovenerol Croat pmid:16603101
Innocenzi D et al. Moderate acne vulgaris: efficacy, tolerance and compliance of oral azithromycin thrice weekly for. 2008 Acta Dermatovenerol Croat pmid:18358103
Moi H et al. Spontaneous Regression of Untreatable Mycoplasma genitalium Urethritis. 2015 Acta Derm. Venereol. pmid:25634824
Cusini M Therapy for Gonococcal and Non-gonococcal Genital Infections is a Major Problem for Clinicians. 2015 Acta Derm. Venereol. pmid:25917593
Unemo M et al. Five-day Azithromycin Treatment Regimen for Mycoplasma genitalium Infection Also Effectively Eradicates Chlamydia trachomatis. 2015 Acta Derm. Venereol. pmid:25823977
Delmée M et al. In vitro susceptibilities of 180 clinical isolates of Haemophilus influenzae to ampicillin, amoxycillin/clavulanate, cefaclor, cefuroxime, cefotaxime, clarithromycin, and azithromycin. 1996 Acta Clin Belg pmid:8858889
Russo V et al. Azithromycin-induced QT prolongation in elderly patient. 2006 Acta Biomed pmid:16856707
Wendel TD 1-day azithromycin was as effective as 7-day doxycycline for nongonococcal urethritis syndrome in men. 1996 Nov-Dec ACP J. Club pmid:8912627
Shunmugaperumal T and Kaur V In Vitro Anti-inflammatory and Antimicrobial Activities of Azithromycin After Loaded in Chitosan- and Tween 20-Based Oil-in-Water Macroemulsion for Acne Management. 2016 AAPS PharmSciTech pmid:26314246
Wei W et al. MPEG-PCL Copolymeric Micelles for Encapsulation of Azithromycin. 2018 AAPS PharmSciTech pmid:29675667