Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

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Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Parasitemia D018512 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Acinetobacter Infections D000151 4 associated lipids
Eyelid Diseases D005141 4 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Meningoencephalitis D008590 4 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Vertigo D014717 4 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Urethral Diseases D014522 4 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Chancroid D002602 4 associated lipids
Tick Infestations D013984 4 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Respiratory Tract Infections D012141 4 associated lipids
Retinitis D012173 4 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Psittacosis D009956 4 associated lipids
Yaws D015001 4 associated lipids
Lymphangitis D008205 4 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Trichomonas Infections D014245 3 associated lipids
Uterine Cervicitis D002575 3 associated lipids
Mitral Valve Stenosis D008946 3 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Corneal Opacity D003318 3 associated lipids
Scrub Typhus D012612 3 associated lipids
Bartonella Infections D001474 3 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Typhus, Endemic Flea-Borne D014437 3 associated lipids
Neglected Diseases D058069 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Giardiasis D005873 3 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Dry Socket D004368 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Braga PC and Piatti G Interference by subinhibitory concentrations of azithromycin with the mechanism of bacterial adhesion to human epithelial cells. 1993 Nov-Dec Chemotherapy pmid:8222872
Minguez F et al. In vitro killing kinetics and postantibiotic effect of josamycin and other macrolides on several bacteria. 1993 May-Jun Chemotherapy pmid:8389685
Díaz Sánchez M et al. [New medications: azithromycin]. 1993 Jul-Sep Rev Med Univ Navarra pmid:8134755
Odugbemi T et al. Single oral dose of azithromycin for therapy of susceptible sexually transmitted diseases: a multicenter open evaluation. 1993 Jul-Sep West Afr J Med pmid:8312208
Wynn RF et al. Azithromycin for cerebral toxoplasmosis in AIDS. 1993 Lancet pmid:8093526
Bailey RL et al. Randomised controlled trial of single-dose azithromycin in treatment of trachoma. 1993 Lancet pmid:8102427
Nahata MC et al. Pharmacokinetics of azithromycin in pediatric patients after oral administration of multiple doses of suspension. 1993 Antimicrob. Agents Chemother. pmid:8383944
Vaara M Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. 1993 Antimicrob. Agents Chemother. pmid:8383945
Brown ST et al. Azithromycin, rifabutin, and rifapentine for treatment and prophylaxis of Mycobacterium avium complex in rats treated with cyclosporine. 1993 Antimicrob. Agents Chemother. pmid:8384809
Cameron DJ Effectiveness of early Lyme disease treatment. 1993 Am. J. Med. pmid:8388627
Hammerschlag MR et al. Single dose of azithromycin for the treatment of genital chlamydial infections in adolescents. 1993 J. Pediatr. pmid:8388950
Melski JW et al. Primary and secondary erythema migrans in central Wisconsin. 1993 Arch Dermatol pmid:8389536
Amacher DE et al. Preclinical toxicology studies with azithromycin: genetic toxicology evaluation. 1993 Mutat. Res. pmid:7685497
Heifets L et al. Mycobacterium avium strains resistant to clarithromycin and azithromycin. 1993 Antimicrob. Agents Chemother. pmid:8031351
Spangler SK and Appelbaum PC Oxyrase, a method which avoids CO2 in the incubation atmosphere for anaerobic susceptibility testing of antibiotics affected by CO2. 1993 J. Clin. Microbiol. pmid:8381817
Berger BW Lyme disease. 1993 Semin Dermatol pmid:8312152
O'Connell S et al. Chronic active toxoplasmosis in an immunocompetent patient. 1993 J. Infect. pmid:8308325
Gingras BA and Jensen JB Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. 1993 Am. J. Trop. Med. Hyg. pmid:8394660
Guerra LG et al. Rapid response of AIDS-related bacillary angiomatosis to azithromycin. 1993 Clin. Infect. Dis. pmid:8399879
Workowski KA et al. Azithromycin in chlamydial urethritis. 1993 JAMA pmid:8411548