Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Aihara Y et al. | Stevens-Johnson syndrome associated with azithromycin followed by transient reactivation of herpes simplex virus infection. | 2004 | Allergy | pmid:14674950 |
| Videler WJ et al. | Lack of efficacy of long-term, low-dose azithromycin in chronic rhinosinusitis: a randomized controlled trial. | 2011 | Allergy | pmid:21884529 |
| Piacentini GL et al. | Azithromycin reduces bronchial hyperresponsiveness and neutrophilic airway inflammation in asthmatic children: a preliminary report. | 2007 Mar-Apr | Allergy Asthma Proc | pmid:17479604 |
| Greenhawt M et al. | Carmine hypersensitivity masquerading as azithromycin hypersensitivity. | 2009 Jan-Feb | Allergy Asthma Proc | pmid:19331724 |
| Mayor MT et al. | Diagnosis and management of gonococcal infections. | 2012 | Am Fam Physician | pmid:23157146 |
| Mohler AM | Treatment of streptococcal pharyngitis. | 2002 | Am Fam Physician | pmid:11996411 |
| Plavchan J | Testing options for the detection of gonorrhea and Chlamydia. | 2013 | Am Fam Physician | pmid:24010388 |
| Mosby JA | Treating acute bronchitis with azithromycin. | 1997 | Am Fam Physician | pmid:9054218 |
| Ebell MH | Short course of antibiotics for acute otitis media treatment. | 2011 | Am Fam Physician | pmid:21888125 |
| Brill JR | Diagnosis and treatment of urethritis in men. | 2010 | Am Fam Physician | pmid:20353145 |
| Mishori R et al. | Chlamydia trachomatis infections: screening, diagnosis, and management. | 2012 | Am Fam Physician | pmid:23316985 |
| Benn K et al. | Bradycardia and Hypothermia Complicating Azithromycin Treatment. | 2017 | Am J Case Rep | pmid:28798290 |
| Haas AN et al. | Azithromycin as an adjunctive treatment of aggressive periodontitis: radiographic findings of a 12-month randomized clinical trial. | 2012 | Am J Dent | pmid:23082385 |
| Zarraga M et al. | Bacillary angiomatosis in an immunocompetent child: a case report and review of the literature. | 2011 | Am J Dermatopathol | pmid:21285862 |
| Nappe TM et al. | Stevens-Johnson syndrome after treatment with azithromycin: an uncommon culprit. | 2016 | Am J Emerg Med | pmid:26194400 |
| Stork CM et al. | Elevated International Normalized Ratio associated with long-term azithromycin therapy in a child with cerebral palsy. | 2011 | Am J Health Syst Pharm | pmid:21593229 |
| Howard KB et al. | Azithromycin versus erythromycin for community-acquired pneumonia: a cost-minimization analysis. | 1999 | Am J Health Syst Pharm | pmid:10478989 |
| Lockwood AM et al. | Azithromycin-induced liver injury. | 2010 | Am J Health Syst Pharm | pmid:20479103 |
| Voytilla KL et al. | Visual compatibility of azithromycin with 24 commonly used drugs during simulated Y-site delivery. | 2002 | Am J Health Syst Pharm | pmid:12004465 |
| Three new studies expand understanding of MAC therapy. | 1996 | Am J Health Syst Pharm | pmid:8899122 |