Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Tuite AR et al. | Impact of Rapid Susceptibility Testing and Antibiotic Selection Strategy on the Emergence and Spread of Antibiotic Resistance in Gonorrhea. | 2017 | J. Infect. Dis. | pmid:28968710 |
González-Beiras C et al. | Single-Dose Azithromycin for the Treatment of Haemophilus ducreyi Skin Ulcers in Papua New Guinea. | 2017 | Clin. Infect. Dis. | pmid:29020192 |
Trembizki E et al. | High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia. | 2017 | J. Med. Microbiol. | pmid:28893363 |
Lu Y et al. | Antibiotics Promote Escherichia coli-Pseudomonas aeruginosa Conjugation through Inhibiting Quorum Sensing. | 2017 | Antimicrob. Agents Chemother. | pmid:28993333 |
Horner PJ and Martin DH | Mycoplasma genitalium Infection in Men. | 2017 | J. Infect. Dis. | pmid:28838074 |
Bradshaw CS et al. | New Horizons in Mycoplasma genitalium Treatment. | 2017 | J. Infect. Dis. | pmid:28838073 |
Paul P et al. | Capillary electrophoresis with capacitively coupled contactless conductivity detection method development and validation for the determination of azithromycin, clarithromycin, and clindamycin. | 2017 | J Sep Sci | pmid:28683179 |
Stieger N et al. | Solution-mediated crystallization of amorphous azithromycin. | 2017 | Pharmazie | pmid:29441902 |
Ito S et al. | Haemophilus influenzae Isolated From Men With Acute Urethritis: Its Pathogenic Roles, Responses to Antimicrobial Chemotherapies, and Antimicrobial Susceptibilities. | 2017 | Sex Transm Dis | pmid:28282645 |
Stieler Stewart AL et al. | Effects of clarithromycin, azithromycin and rifampicin on terbutaline-induced sweating in foals. | 2017 | Equine Vet. J. | pmid:28238211 |
Allan RN et al. | Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms. | 2017 | Nitric Oxide | pmid:28235635 |
Wiesenfeld HC | Screening for Chlamydia trachomatis Infections in Women. | 2017 | N. Engl. J. Med. | pmid:28225683 |
Shmarina G et al. | Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression. | 2017 | Int. Arch. Allergy Immunol. | pmid:28219060 |
Ramappa M et al. | Successful Medical Management of Presumptive Pythium insidiosum Keratitis. | 2017 | Cornea | pmid:28207431 |
Koeva M et al. | An Antipersister Strategy for Treatment of Chronic Pseudomonas aeruginosa Infections. | 2017 | Antimicrob. Agents Chemother. | pmid:28923873 |
Ito A et al. | A Case of Community-Acquired Pneumonia Due to Legionella pneumophila Serogroup 9 Wherein Initial Treatment with Single-Dose Oral Azithromycin Appeared Useful. | 2017 | Jpn. J. Infect. Dis. | pmid:28890505 |
Saiz JC and MartÃn-Acebes MA | Reply to Iannetta et al., "Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells". | 2017 | Antimicrob. Agents Chemother. | pmid:28839084 |
Iannetta M et al. | Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells. | 2017 | Antimicrob. Agents Chemother. | pmid:28839081 |
Cluver C et al. | Interventions for treating genital Chlamydia trachomatis infection in pregnancy. | 2017 | Cochrane Database Syst Rev | pmid:28937705 |
Houinei W et al. | Haemophilus ducreyi DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea. | 2017 | PLoS Negl Trop Dis | pmid:28489855 |
Nenoff P et al. | [Non-viral sexually transmitted infections - Epidemiology, clinical manifestations, diagnostics and therapy : Part 1: Gonococci]. | 2017 | Hautarzt | pmid:27981386 |
Rutenberg D et al. | Efficacy of Tulathromycin for the Treatment of Foals with Mild to Moderate Bronchopneumonia. | 2017 | J. Vet. Intern. Med. | pmid:28421633 |
Trifirò G et al. | Use of azithromycin and risk of ventricular arrhythmia. | 2017 | CMAJ | pmid:28420680 |
Amza A et al. | A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children. | 2017 | Clin. Infect. Dis. | pmid:27956455 |
Papp JR et al. | Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA. | 2017 | Emerging Infect. Dis. | pmid:28418303 |
Liu Y et al. | Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. | 2017 | Life Sci. | pmid:27916734 |
Vandooren J et al. | Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. | 2017 | PLoS ONE | pmid:28369077 |
Valdés SO et al. | Cardiac Arrest in Pediatric Patients Receiving Azithromycin. | 2017 | J. Pediatr. | pmid:27912925 |
Chavada VD et al. | Surface plasmon resonance based selective and sensitive colorimetric determination of azithromycin using unmodified silver nanoparticles in pharmaceuticals and human plasma. | 2017 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:27419643 |
Agarwal E et al. | Locally Delivered 0.5% Azithromycin as an Adjunct to Non-Surgical Treatment in Patients With Chronic Periodontitis With Type 2 Diabetes: A Randomized Controlled Clinical Trial. | 2017 | J. Periodontol. | pmid:22655911 |
Foerster S et al. | A new rapid resazurin-based microdilution assay for antimicrobial susceptibility testing of Neisseria gonorrhoeae. | 2017 | J. Antimicrob. Chemother. | pmid:28431096 |
Murphy TK et al. | A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder. | 2017 | J Child Adolesc Psychopharmacol | pmid:28358599 |
Eyre DW et al. | WGS to predict antibiotic MICs for Neisseria gonorrhoeae. | 2017 | J. Antimicrob. Chemother. | pmid:28333355 |
Shan LS et al. | Effects of methylprednisolone or immunoglobulin when added to standard treatment with intravenous azithromycin for refractory Mycoplasma pneumoniae pneumonia in children. | 2017 | World J Pediatr | pmid:28130749 |
Waites KB et al. | In Vitro Activities of Lefamulin and Other Antimicrobial Agents against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China. | 2017 | Antimicrob. Agents Chemother. | pmid:27855075 |
Thompson DF and Ramos CL | Antibiotic-Induced Rash in Patients With Infectious Mononucleosis. | 2017 | Ann Pharmacother | pmid:27620494 |
Rajesh AM and Popat KM | Taste masking of azithromycin by resin complex and sustained release through interpenetrating polymer network with functionalized biopolymers. | 2017 | Drug Dev Ind Pharm | pmid:27600608 |
Purssell A et al. | Azithromycin and Doxycycline Attenuation of Acanthamoeba Virulence in a Human Corneal Tissue Model. | 2017 | J. Infect. Dis. | pmid:27578848 |
Romero L et al. | Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. | 2017 | Cochrane Database Syst Rev | pmid:29226307 |
Dror T et al. | Microbiota manipulation for weight change. | 2017 | Microb. Pathog. | pmid:26792677 |
Lusk MJ et al. | Cervicitis: a prospective observational study of empiric azithromycin treatment in women with cervicitis and non-specific cervicitis. | 2017 | Int J STD AIDS | pmid:26792283 |
Burr SE et al. | Does azithromycin given to women in labour decrease ocular bacterial infection in neonates? A double-blind, randomized trial. | 2017 | BMC Infect. Dis. | pmid:29282015 |
Marks M and Mabey D | Single-dose azithromycin to treat latent yaws. | 2017 | Lancet Glob Health | pmid:29107622 |
Mitjà O et al. | Effectiveness of single-dose azithromycin to treat latent yaws: a longitudinal comparative cohort study. | 2017 | Lancet Glob Health | pmid:29107621 |
Watson JR et al. | Healthcare Claims Data: An Underutilized Tool for Pediatric Outpatient Antimicrobial Stewardship. | 2017 | Clin. Infect. Dis. | pmid:28329388 |
Thompson CN et al. | Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal. | 2017 | Clin. Infect. Dis. | pmid:28329181 |
Emerging risk of untreatable gonorrhea and what to do about it. | 2017 | Can Fam Physician | pmid:28292798 | |
Halhal B et al. | Pertussis Outbreak Among Soldiers During Basic Training: The Need for Updated Protocols. | 2017 | Mil Med | pmid:28291499 |
Çelik Payçu DG and Büyükbaba Boral Ö | [Effects of azithromycin and Chlorella vulgaris treatment on certain cytokine values and NK cell activity in an acute murine toxoplasmosis model]. | 2017 | Mikrobiyol Bul | pmid:28283010 |
Garcia-Vidal C et al. | Levofloxacin versus azithromycin for treating legionella pneumonia: a propensity score analysis. | 2017 | Clin. Microbiol. Infect. | pmid:28267637 |